ENSG00000203485

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000330634 ENSG00000203485 No_inf pgKDN_inf INF2 protein_coding protein_coding 57.27222 80.11085 42.65863 2.237498 1.871864 -0.909002 3.766313 1.590666 3.5919949 0.5366712 1.3078271 1.1701241 0.07638333 0.020075 0.085600 0.065525 0.68137449 0.003600922 FALSE TRUE
ENST00000392634 ENSG00000203485 No_inf pgKDN_inf INF2 protein_coding protein_coding 57.27222 80.11085 42.65863 2.237498 1.871864 -0.909002 3.514274 9.244980 0.5617198 1.3361552 0.5617198 -4.0168497 0.04791667 0.114950 0.012400 -0.102550 0.02015801 0.003600922 FALSE TRUE
ENST00000398337 ENSG00000203485 No_inf pgKDN_inf INF2 protein_coding protein_coding 57.27222 80.11085 42.65863 2.237498 1.871864 -0.909002 5.141329 4.614952 4.9884110 0.4631975 0.7440261 0.1120310 0.09709167 0.057950 0.115600 0.057650 0.38813200 0.003600922 FALSE TRUE
ENST00000674631 ENSG00000203485 No_inf pgKDN_inf INF2 protein_coding protein_coding 57.27222 80.11085 42.65863 2.237498 1.871864 -0.909002 14.850268 17.587061 10.8485336 0.7970450 0.6995227 -0.6965052 0.26775000 0.219300 0.257450 0.038150 0.83695530 0.003600922 FALSE TRUE
ENST00000675603 ENSG00000203485 No_inf pgKDN_inf INF2 protein_coding protein_coding_CDS_not_defined 57.27222 80.11085 42.65863 2.237498 1.871864 -0.909002 1.763230 4.758151 0.0000000 1.8411669 0.0000000 -8.8972861 0.02268333 0.057675 0.000000 -0.057675 0.05484700 0.003600922 FALSE FALSE
ENST00000675797 ENSG00000203485 No_inf pgKDN_inf INF2 protein_coding nonsense_mediated_decay 57.27222 80.11085 42.65863 2.237498 1.871864 -0.909002 9.549108 13.082789 11.7559179 1.6899175 1.0010063 -0.1541586 0.17341667 0.165350 0.274775 0.109425 0.29523226 0.003600922 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000203485 E001 0.1176306 0.0117241844 2.475022e-01   14 104681146 104681582 437 + 0.130 0.000 -11.158
ENSG00000203485 E002 0.2536433 0.0159610843 6.114298e-01   14 104684063 104684932 870 + 0.000 0.128 12.712
ENSG00000203485 E003 0.0000000       14 104688307 104688572 266 +      
ENSG00000203485 E004 0.3807797 0.0306582528 3.378446e-01   14 104689152 104689245 94 + 0.000 0.181 13.183
ENSG00000203485 E005 0.0000000       14 104689523 104689569 47 +      
ENSG00000203485 E006 0.3707734 0.0167696401 1.000000e+00   14 104689570 104689605 36 + 0.130 0.128 -0.020
ENSG00000203485 E007 1.0871688 0.0110590266 4.023028e-02 0.1944421547 14 104689606 104689617 12 + 0.490 0.181 -2.020
ENSG00000203485 E008 1.8407679 0.0070962209 2.713828e-01 0.5651040352 14 104689618 104689620 3 + 0.537 0.376 -0.827
ENSG00000203485 E009 1.8407679 0.0070962209 2.713828e-01 0.5651040352 14 104689621 104689622 2 + 0.537 0.376 -0.827
ENSG00000203485 E010 9.9481925 0.0076088270 4.632734e-01 0.7332273313 14 104689623 104689739 117 + 0.955 1.033 0.290
ENSG00000203485 E011 0.0000000       14 104695990 104696490 501 +      
ENSG00000203485 E012 0.1265070 0.0122659390 1.000000e+00   14 104699368 104699598 231 + 0.000 0.069 11.765
ENSG00000203485 E013 0.1265070 0.0122659390 1.000000e+00   14 104699599 104699803 205 + 0.000 0.069 11.765
ENSG00000203485 E014 0.0000000       14 104699804 104699826 23 +      
ENSG00000203485 E015 0.0000000       14 104699827 104699834 8 +      
ENSG00000203485 E016 0.0000000       14 104700678 104700709 32 +      
ENSG00000203485 E017 0.1272623 0.0123169883 1.000000e+00   14 104700737 104700864 128 + 0.000 0.069 11.765
ENSG00000203485 E018 3.6109532 0.0798958651 6.789635e-01 0.8672606937 14 104701357 104701365 9 + 0.578 0.664 0.373
ENSG00000203485 E019 54.7432588 0.0040422281 7.283927e-02 0.2741644513 14 104701366 104701756 391 + 1.770 1.687 -0.281
ENSG00000203485 E020 1.3523952 0.0132257256 3.921714e-01 0.6772123776 14 104702512 104703104 593 + 0.438 0.308 -0.757
ENSG00000203485 E021 33.9707455 0.0036900973 8.920065e-01 0.9641747849 14 104703105 104703220 116 + 1.515 1.511 -0.012
ENSG00000203485 E022 14.9590272 0.0027590879 3.242584e-01 0.6166923539 14 104703295 104703305 11 + 1.222 1.148 -0.264
ENSG00000203485 E023 36.7548595 0.0090521514 3.492261e-01 0.6395992970 14 104703306 104703454 149 + 1.583 1.527 -0.192
ENSG00000203485 E024 14.8621264 0.0206339357 7.833912e-01 0.9166203287 14 104703916 104703949 34 + 1.184 1.164 -0.074
ENSG00000203485 E025 21.1802656 0.0089198582 1.531761e-05 0.0004923362 14 104703950 104704809 860 + 1.505 1.189 -1.103
ENSG00000203485 E026 33.1886288 0.0026514168 5.335108e-01 0.7840215013 14 104706035 104706152 118 + 1.524 1.493 -0.108
ENSG00000203485 E027 20.3426254 0.0075299997 9.728315e-01 0.9949138890 14 104706153 104706176 24 + 1.297 1.299 0.007
ENSG00000203485 E028 0.8790336 0.0123780671 2.736720e-01 0.5673954392 14 104706600 104706697 98 + 0.130 0.308 1.565
ENSG00000203485 E029 36.3256290 0.0099216071 7.924320e-01 0.9207821960 14 104706910 104707051 142 + 1.550 1.536 -0.050
ENSG00000203485 E030 45.3642428 0.0003175821 2.266547e-01 0.5148806856 14 104707253 104707847 595 + 1.591 1.653 0.212
ENSG00000203485 E031 7.2768139 0.0043441120 2.176859e-01 0.5041943926 14 104707848 104707863 16 + 0.971 0.846 -0.475
ENSG00000203485 E032 31.1157754 0.0004332764 4.308347e-02 0.2024031709 14 104707864 104708002 139 + 1.546 1.439 -0.368
ENSG00000203485 E033 0.1265070 0.0122659390 1.000000e+00   14 104708291 104708435 145 + 0.000 0.069 11.765
ENSG00000203485 E034 29.8593390 0.0004582214 2.558705e-02 0.1475948874 14 104708436 104708531 96 + 1.537 1.417 -0.415
ENSG00000203485 E035 22.7679598 0.0047618633 3.413758e-01 0.6329454960 14 104708532 104708587 56 + 1.387 1.325 -0.215
ENSG00000203485 E036 1.6504799 0.0082003328 3.142877e-03 0.0357040274 14 104708588 104708670 83 + 0.000 0.510 15.270
ENSG00000203485 E037 22.8168410 0.0006084960 9.211703e-01 0.9754269744 14 104708671 104708732 62 + 1.348 1.345 -0.008
ENSG00000203485 E038 16.8729706 0.0008617893 9.106304e-01 0.9716700178 14 104709281 104709293 13 + 1.213 1.226 0.044
ENSG00000203485 E039 36.9883932 0.0020094786 2.487097e-01 0.5395735421 14 104709294 104709383 90 + 1.587 1.529 -0.197
ENSG00000203485 E040 38.3181921 0.0026675129 8.590206e-01 0.9509527433 14 104709620 104709705 86 + 1.567 1.561 -0.020
ENSG00000203485 E041 40.7311468 0.0028591585 3.820703e-01 0.6683118929 14 104710088 104710188 101 + 1.617 1.575 -0.143
ENSG00000203485 E042 0.8781220 0.0220187568 2.774495e-01 0.5707367947 14 104710725 104710881 157 + 0.130 0.308 1.565
ENSG00000203485 E043 1.2488980 0.0109876715 3.734060e-01 0.6611062145 14 104710882 104710918 37 + 0.230 0.376 0.980
ENSG00000203485 E044 1.0053870 0.0113355115 1.927151e-01 0.4725356624 14 104710919 104710936 18 + 0.130 0.343 1.788
ENSG00000203485 E045 28.1656059 0.0004747549 9.012183e-02 0.3118387520 14 104710937 104710989 53 + 1.496 1.402 -0.323
ENSG00000203485 E046 18.1859094 0.0007562459 3.184663e-01 0.6112392880 14 104710990 104711007 18 + 1.297 1.230 -0.235
ENSG00000203485 E047 0.1268540 0.0123229365 1.000000e+00   14 104711008 104711011 4 + 0.000 0.069 11.765
ENSG00000203485 E048 1.7504228 0.0077788579 3.515868e-01 0.6418168977 14 104711012 104711078 67 + 0.311 0.461 0.855
ENSG00000203485 E049 16.6093211 0.0008615808 7.115130e-01 0.8833983500 14 104711079 104711083 5 + 1.231 1.208 -0.084
ENSG00000203485 E050 38.6088320 0.0004687061 7.140350e-01 0.8848742484 14 104711084 104711186 103 + 1.550 1.573 0.079
ENSG00000203485 E051 35.6401217 0.0029158398 6.210397e-01 0.8363752478 14 104711629 104711699 71 + 1.510 1.542 0.110
ENSG00000203485 E052 41.8558813 0.0006961347 3.568220e-01 0.6466462571 14 104712433 104712553 121 + 1.628 1.587 -0.140
ENSG00000203485 E053 0.2435110 0.0161857511 5.758293e-01   14 104712713 104712827 115 + 0.130 0.069 -1.020
ENSG00000203485 E054 14.8702988 0.0009540133 7.539364e-01 0.9031878773 14 104712828 104712832 5 + 1.184 1.164 -0.073
ENSG00000203485 E055 52.1575886 0.0003036337 6.113743e-01 0.8308704974 14 104712833 104712992 160 + 1.706 1.688 -0.061
ENSG00000203485 E056 0.8710761 0.0129919312 8.113897e-01 0.9305245249 14 104713202 104713206 5 + 0.230 0.269 0.302
ENSG00000203485 E057 50.6298092 0.0025136523 3.893159e-01 0.6750594023 14 104713207 104713304 98 + 1.706 1.670 -0.124
ENSG00000203485 E058 28.8400892 0.0004873923 3.647858e-01 0.6533270790 14 104713305 104713309 5 + 1.476 1.428 -0.166
ENSG00000203485 E059 26.7611940 0.0005077938 6.512704e-01 0.8530853257 14 104713445 104713448 4 + 1.428 1.405 -0.079
ENSG00000203485 E060 82.7815302 0.0007117841 1.175758e-01 0.3622790873 14 104713449 104713606 158 + 1.926 1.875 -0.172
ENSG00000203485 E061 1.3959863 0.0307502203 8.723484e-03 0.0733294020 14 104713821 104713933 113 + 0.000 0.461 14.927
ENSG00000203485 E062 53.6760671 0.0003187871 8.411812e-01 0.9430542838 14 104714203 104714283 81 + 1.709 1.705 -0.015
ENSG00000203485 E063 56.7529747 0.0002582911 6.829389e-02 0.2637628124 14 104714284 104714395 112 + 1.777 1.706 -0.241
ENSG00000203485 E064 50.4619689 0.0002943860 8.750786e-01 0.9573281319 14 104714396 104714507 112 + 1.682 1.679 -0.009
ENSG00000203485 E065 44.5299448 0.0003192679 9.967541e-02 0.3298738786 14 104714508 104714588 81 + 1.567 1.652 0.288
ENSG00000203485 E066 100.9248545 0.0003662027 3.800384e-01 0.6666503205 14 104714589 104714856 268 + 1.954 1.986 0.110
ENSG00000203485 E067 16.0545261 0.0145619556 2.425503e-01 0.5321728928 14 104714857 104715280 424 + 1.265 1.169 -0.342
ENSG00000203485 E068 1.7371096 0.2716198858 8.122176e-01 0.9309356478 14 104715281 104715283 3 + 0.439 0.406 -0.173
ENSG00000203485 E069 27.8003116 0.0072552356 9.433909e-05 0.0022674174 14 104715284 104715340 57 + 1.204 1.502 1.038
ENSG00000203485 E070 7.7896229 0.0019211763 1.102944e-03 0.0161559414 14 104715725 104715832 108 + 0.617 1.005 1.538
ENSG00000203485 E071 11.6972148 0.0134259801 6.170861e-05 0.0015780901 14 104715833 104716017 185 + 0.715 1.174 1.735
ENSG00000203485 E072 3.4027232 0.0088540679 9.900909e-03 0.0797247537 14 104717548 104717562 15 + 0.311 0.710 1.980
ENSG00000203485 E073 11.0783699 0.0014289453 3.327217e-06 0.0001319486 14 104717563 104717646 84 + 0.652 1.159 1.944
ENSG00000203485 E074 288.0788186 0.0014213466 8.166762e-05 0.0020062958 14 104718795 104722535 3741 + 2.362 2.456 0.313

Help

Please Click HERE to learn more details about the results from DEXseq.