ENSG00000204428

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000375863 ENSG00000204428 No_inf pgKDN_inf LY6G5C protein_coding protein_coding 7.376853 8.98214 6.282693 0.9709669 1.507214 -0.514987 0.8390427 0.1243939 1.005794 0.1243939 0.1072491 2.9180678 0.1359417 0.013775 0.183250 0.169475 0.03936784 0.03936784 FALSE TRUE
ENST00000461572 ENSG00000204428 No_inf pgKDN_inf LY6G5C protein_coding protein_coding_CDS_not_defined 7.376853 8.98214 6.282693 0.9709669 1.507214 -0.514987 3.0455217 3.2929165 2.083048 0.7033330 1.2503968 -0.6581349 0.3807250 0.354775 0.238825 -0.115950 0.78836882 0.03936784   FALSE
ENST00000474395 ENSG00000204428 No_inf pgKDN_inf LY6G5C protein_coding protein_coding_CDS_not_defined 7.376853 8.98214 6.282693 0.9709669 1.507214 -0.514987 2.2473824 3.6229871 1.816393 0.8450776 0.7337247 -0.9921587 0.2784750 0.402125 0.254900 -0.147225 0.78300545 0.03936784   FALSE
MSTRG.24448.4 ENSG00000204428 No_inf pgKDN_inf LY6G5C protein_coding   7.376853 8.98214 6.282693 0.9709669 1.507214 -0.514987 0.8741199 1.3723391 1.130677 0.8576849 0.5251414 -0.2772207 0.1537167 0.173000 0.271900 0.098900 0.85030232 0.03936784   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000204428 E001 0.0000000       6 31676684 31676699 16 -      
ENSG00000204428 E002 0.0000000       6 31676700 31676707 8 -      
ENSG00000204428 E003 3.1134267 0.093294361 0.226353316 0.51441681 6 31676708 31676847 140 - 0.486 0.669 0.832
ENSG00000204428 E004 3.0937520 0.005343395 0.560347283 0.80097984 6 31676848 31676956 109 - 0.562 0.629 0.300
ENSG00000204428 E005 5.3429073 0.003413331 0.095087579 0.32092950 6 31676957 31677120 164 - 0.683 0.852 0.676
ENSG00000204428 E006 3.4452712 0.004651887 0.886130185 0.96194738 6 31679101 31679268 168 - 0.656 0.629 -0.115
ENSG00000204428 E007 0.7434642 0.014534896 0.679394715 0.86754444 6 31679269 31680158 890 - 0.201 0.259 0.470
ENSG00000204428 E008 0.1176306 0.012233853 0.379490919   6 31680159 31680252 94 - 0.112 0.000 -8.930
ENSG00000204428 E009 1.8663250 0.010039884 0.229385849 0.51804352 6 31680253 31681067 815 - 0.338 0.511 0.929
ENSG00000204428 E010 1.3295516 0.408679445 0.352902477 0.64282532 6 31681181 31681229 49 - 0.485 0.259 -1.334
ENSG00000204428 E011 2.7124414 0.005647608 0.950860511 0.98753559 6 31681230 31681347 118 - 0.562 0.562 0.000
ENSG00000204428 E012 1.7046619 0.009399102 0.230441476 0.51898407 6 31681348 31681401 54 - 0.525 0.347 -0.945
ENSG00000204428 E013 1.8212534 0.044224170 0.149287045 0.41154993 6 31681402 31681512 111 - 0.562 0.347 -1.115
ENSG00000204428 E014 2.4690600 0.007262007 0.874614216 0.95711562 6 31681646 31681960 315 - 0.525 0.537 0.055
ENSG00000204428 E015 1.3152258 0.010172860 0.005468929 0.05283182 6 31683050 31683341 292 - 0.562 0.148 -2.700
ENSG00000204428 E016 0.0000000       6 31683988 31684040 53 -      

Help

Please Click HERE to learn more details about the results from DEXseq.