ENSG00000204482

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000376090 ENSG00000204482 No_inf pgKDN_inf LST1 protein_coding protein_coding 254.8928 87.40702 306.1891 10.32619 19.43721 1.808484 98.63065 30.166182 131.99815 1.1304112 2.4070856 2.1291448 0.38773333 0.362725 0.435725 0.073000 0.66138961 0.01038314    
ENST00000376096 ENSG00000204482 No_inf pgKDN_inf LST1 protein_coding protein_coding 254.8928 87.40702 306.1891 10.32619 19.43721 1.808484 31.45252 6.203831 44.42785 0.7976073 3.2095932 2.8382341 0.11255000 0.071250 0.145275 0.074025 0.01038314 0.01038314    
ENST00000433492 ENSG00000204482 No_inf pgKDN_inf LST1 protein_coding protein_coding 254.8928 87.40702 306.1891 10.32619 19.43721 1.808484 36.80795 15.193409 28.90697 8.8228762 17.2143694 0.9275214 0.13260000 0.144275 0.085700 -0.058575 0.99508666 0.01038314    
ENST00000438075 ENSG00000204482 No_inf pgKDN_inf LST1 protein_coding protein_coding 254.8928 87.40702 306.1891 10.32619 19.43721 1.808484 18.41698 7.903676 21.63703 1.8121566 1.2407636 1.4517492 0.08031667 0.100125 0.071550 -0.028575 0.88524554 0.01038314    
ENST00000464526 ENSG00000204482 No_inf pgKDN_inf LST1 protein_coding retained_intron 254.8928 87.40702 306.1891 10.32619 19.43721 1.808484 12.47142 6.402487 10.05764 0.3716305 0.3633237 0.6507692 0.05568333 0.076725 0.033450 -0.043275 0.14085673 0.01038314    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000204482 E001 0.2362687 0.0157577407 1.000000e+00   6 31586124 31586193 70 + 0.107 0.000 -8.167
ENSG00000204482 E002 0.2356421 0.0157019094 1.000000e+00   6 31586194 31586216 23 + 0.107 0.000 -9.844
ENSG00000204482 E003 0.2356421 0.0157019094 1.000000e+00   6 31586217 31586219 3 + 0.107 0.000 -9.844
ENSG00000204482 E004 12.6752906 0.0011384164 1.033945e-01 3.361488e-01 6 31586220 31586276 57 + 1.118 0.962 -0.573
ENSG00000204482 E005 17.6793814 0.0032669453 2.886906e-02 1.592212e-01 6 31586277 31586315 39 + 1.259 1.070 -0.676
ENSG00000204482 E006 0.9633725 0.0120276622 9.748991e-01 9.954114e-01 6 31586699 31586807 109 + 0.264 0.269 0.037
ENSG00000204482 E007 2.3687559 0.0056326094 1.964213e-02 1.255582e-01 6 31586848 31586894 47 + 0.562 0.155 -2.626
ENSG00000204482 E008 6.8133277 0.0020515816 2.072847e-01 4.909516e-01 6 31586895 31586939 45 + 0.878 0.724 -0.610
ENSG00000204482 E009 19.9683823 0.0015752388 5.588022e-01 8.002917e-01 6 31587022 31587053 32 + 1.256 1.299 0.151
ENSG00000204482 E010 27.4682455 0.0040608971 5.481727e-01 7.933331e-01 6 31587054 31587085 32 + 1.410 1.368 -0.145
ENSG00000204482 E011 29.7976001 0.0013302198 9.761588e-01 9.960011e-01 6 31587086 31587106 21 + 1.433 1.435 0.006
ENSG00000204482 E012 28.1732119 0.0022314784 3.230415e-01 6.158114e-01 6 31587107 31587116 10 + 1.426 1.360 -0.229
ENSG00000204482 E013 40.5717152 0.0004263802 1.211656e-02 9.107940e-02 6 31587117 31587199 83 + 1.595 1.455 -0.481
ENSG00000204482 E014 77.7148816 0.0002783781 1.941139e-03 2.498649e-02 6 31587200 31587254 55 + 1.868 1.745 -0.417
ENSG00000204482 E015 79.3255376 0.0002849801 1.552649e-01 4.211032e-01 6 31587255 31587299 45 + 1.862 1.807 -0.184
ENSG00000204482 E016 64.3867157 0.0002487982 5.757704e-01 8.101746e-01 6 31587300 31587315 16 + 1.765 1.741 -0.080
ENSG00000204482 E017 50.6228114 0.0003977968 1.829550e-01 4.596382e-01 6 31587316 31587318 3 + 1.672 1.608 -0.220
ENSG00000204482 E018 17.6371394 0.0143060388 1.869850e-01 4.648610e-01 6 31587319 31587640 322 + 1.183 1.299 0.409
ENSG00000204482 E019 18.1772024 0.0008002451 3.123010e-03 3.555011e-02 6 31587641 31587668 28 + 1.162 1.376 0.750
ENSG00000204482 E020 32.9523347 0.0004322442 2.582251e-02 1.484848e-01 6 31587669 31587733 65 + 1.439 1.564 0.427
ENSG00000204482 E021 5.4162248 0.0026880251 6.183631e-06 2.256125e-04 6 31587734 31587815 82 + 0.562 1.070 2.018
ENSG00000204482 E022 9.0534777 0.0014727584 2.294744e-01 5.180705e-01 6 31587816 31587943 128 + 0.917 1.037 0.445
ENSG00000204482 E023 18.9456382 0.0007418040 1.221426e-01 3.696146e-01 6 31587944 31587948 5 + 1.213 1.326 0.396
ENSG00000204482 E024 22.5886915 0.0005973039 2.907223e-02 1.599329e-01 6 31587949 31587966 18 + 1.275 1.421 0.505
ENSG00000204482 E025 27.9313751 0.0044326604 2.651428e-15 4.612971e-13 6 31587967 31588496 530 + 1.221 1.706 1.673
ENSG00000204482 E026 9.1180824 0.0338904355 1.160337e-02 8.864252e-02 6 31588497 31588517 21 + 0.854 1.156 1.117
ENSG00000204482 E027 67.5300964 0.0002092142 9.381405e-01 9.821929e-01 6 31588518 31588562 45 + 1.780 1.777 -0.011
ENSG00000204482 E028 170.3576982 0.0037752605 7.022577e-02 2.681266e-01 6 31588563 31588909 347 + 2.192 2.132 -0.200

Help

Please Click HERE to learn more details about the results from DEXseq.