ENSG00000204592

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000376630 ENSG00000204592 No_inf pgKDN_inf HLA-E protein_coding protein_coding 241.9842 172.7101 276.9187 1.981968 2.329774 0.681079 222.76801 166.650481 251.2803 1.7067074 2.566927 0.5924427 0.9262417 0.964975 0.90750 -0.057475 1.548271e-07 1.548271e-07 FALSE  
ENST00000493699 ENSG00000204592 No_inf pgKDN_inf HLA-E protein_coding retained_intron 241.9842 172.7101 276.9187 1.981968 2.329774 0.681079 15.67336 3.469304 21.8393 0.8137623 1.375291 2.6507164 0.0591000 0.020050 0.07885 0.058800 3.280921e-03 1.548271e-07 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000204592 E001 0.126507 1.233896e-02 3.758162e-01   6 30489509 30489509 1 + 0.000 0.111 8.747
ENSG00000204592 E002 0.243511 1.648962e-02 7.857364e-01   6 30489510 30489511 2 + 0.081 0.111 0.507
ENSG00000204592 E003 48.813517 1.110197e-02 7.769809e-03 6.770995e-02 6 30489512 30489595 84 + 1.758 1.590 -0.569
ENSG00000204592 E004 4.468584 3.545940e-03 2.714876e-01 5.652349e-01 6 30489596 30489725 130 + 0.788 0.653 -0.552
ENSG00000204592 E005 262.056165 8.071613e-05 7.494366e-06 2.662722e-04 6 30489726 30489995 270 + 2.450 2.367 -0.277
ENSG00000204592 E006 6.727553 6.216951e-02 5.507211e-01 7.948458e-01 6 30489996 30490239 244 + 0.842 0.934 0.349
ENSG00000204592 E007 366.460428 7.550321e-05 1.236702e-08 8.673637e-07 6 30490240 30490515 276 + 2.597 2.509 -0.294
ENSG00000204592 E008 328.309226 8.644816e-05 2.154236e-13 3.041533e-11 6 30491137 30491412 276 + 2.562 2.440 -0.407
ENSG00000204592 E009 279.191772 7.785879e-05 4.466214e-05 1.215955e-03 6 30491537 30491653 117 + 2.473 2.400 -0.243
ENSG00000204592 E010 203.078566 9.182051e-05 1.305576e-01 3.832730e-01 6 30492404 30492436 33 + 2.319 2.287 -0.105
ENSG00000204592 E011 228.717545 8.628403e-05 2.593605e-02 1.489297e-01 6 30492541 30492583 43 + 2.375 2.332 -0.146
ENSG00000204592 E012 1420.441254 4.048270e-05 7.250665e-55 1.629406e-51 6 30492749 30494194 1446 + 3.104 3.201 0.322

Help

Please Click HERE to learn more details about the results from DEXseq.