ENSG00000204619

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000376758 ENSG00000204619 No_inf pgKDN_inf PPP1R11 protein_coding protein_coding 20.33677 19.23073 21.87811 1.139783 0.7501914 0.185984 1.5809214 2.914097 0.886066 0.3506415 0.5121085 -1.7063141 0.07958333 0.152450 0.0390 -0.113450 0.24578237 0.02688779   FALSE
ENST00000376763 ENSG00000204619 No_inf pgKDN_inf PPP1R11 protein_coding protein_coding 20.33677 19.23073 21.87811 1.139783 0.7501914 0.185984 0.4494018 1.348205 0.000000 1.3482053 0.0000000 -7.0855578 0.02265833 0.067975 0.0000 -0.067975 0.84330063 0.02688779   FALSE
ENST00000376772 ENSG00000204619 No_inf pgKDN_inf PPP1R11 protein_coding protein_coding 20.33677 19.23073 21.87811 1.139783 0.7501914 0.185984 17.7161161 14.716449 20.773415 1.3929536 0.4174384 0.4970231 0.86880000 0.767350 0.9512 0.183850 0.02688779 0.02688779 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000204619 E001 0.3806233 0.0159636442 0.110547570   6 30066709 30067009 301 + 0.000 0.236 10.910
ENSG00000204619 E002 0.0000000       6 30067198 30067204 7 +      
ENSG00000204619 E003 18.0206352 0.0107640658 0.039953734 0.19376537 6 30067205 30067479 275 + 1.351 1.201 -0.525
ENSG00000204619 E004 0.1186381 0.0118785592 0.517682363   6 30067543 30067575 33 + 0.097 0.000 -11.744
ENSG00000204619 E005 0.4910492 0.1384745299 0.972824406   6 30067576 30067625 50 + 0.176 0.170 -0.054
ENSG00000204619 E006 0.4910492 0.1384745299 0.972824406   6 30067626 30067664 39 + 0.176 0.170 -0.054
ENSG00000204619 E007 1.1065895 0.0106255957 0.784522187 0.91683854 6 30068206 30068278 73 + 0.300 0.343 0.269
ENSG00000204619 E008 0.9992474 0.0133893669 0.167922176 0.43880533 6 30068279 30068353 75 + 0.176 0.388 1.532
ENSG00000204619 E009 2.7568462 0.0053079397 0.002703057 0.03190002 6 30068354 30068589 236 + 0.300 0.726 2.117
ENSG00000204619 E010 19.0046627 0.0007772839 0.997251060 1.00000000 6 30068590 30068698 109 + 1.300 1.301 0.003
ENSG00000204619 E011 118.6754483 0.0048956803 0.702189297 0.87884059 6 30069104 30070333 1230 + 2.073 2.081 0.024

Help

Please Click HERE to learn more details about the results from DEXseq.