ENSG00000204842

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000475132 ENSG00000204842 No_inf pgKDN_inf ATXN2 protein_coding protein_coding 25.20063 27.92812 23.26889 1.044873 1.761937 -0.2632125 0.7737461 1.8319727 0.0000000 1.0596298 0.0000000 -7.5251079 0.02777500 0.062225 0.000000 -0.062225 0.51860462 0.04718118    
ENST00000535949 ENSG00000204842 No_inf pgKDN_inf ATXN2 protein_coding protein_coding 25.20063 27.92812 23.26889 1.044873 1.761937 -0.2632125 1.3276947 0.1477526 2.0349558 0.1477526 1.2060723 3.6963337 0.05895833 0.005600 0.099900 0.094300 0.71136390 0.04718118 FALSE  
ENST00000550236 ENSG00000204842 No_inf pgKDN_inf ATXN2 protein_coding protein_coding 25.20063 27.92812 23.26889 1.044873 1.761937 -0.2632125 1.4202647 0.8439612 0.6777809 0.8439612 0.6777809 -0.3122215 0.05822500 0.032050 0.032625 0.000575 1.00000000 0.04718118 FALSE  
ENST00000645162 ENSG00000204842 No_inf pgKDN_inf ATXN2 protein_coding protein_coding_CDS_not_defined 25.20063 27.92812 23.26889 1.044873 1.761937 -0.2632125 1.0748260 0.5110065 2.0966577 0.5110065 0.7349422 2.0155825 0.04286667 0.016575 0.087200 0.070625 0.36051941 0.04718118 FALSE  
ENST00000673273 ENSG00000204842 No_inf pgKDN_inf ATXN2 protein_coding nonsense_mediated_decay 25.20063 27.92812 23.26889 1.044873 1.761937 -0.2632125 0.9080924 1.7017965 0.1417134 0.2928153 0.1417134 -3.4960904 0.03497500 0.060950 0.005575 -0.055375 0.04718118 0.04718118 TRUE  
MSTRG.7198.10 ENSG00000204842 No_inf pgKDN_inf ATXN2 protein_coding   25.20063 27.92812 23.26889 1.044873 1.761937 -0.2632125 5.8881138 7.3116856 5.5112565 0.7880668 0.6493172 -0.4071792 0.23302500 0.260150 0.234975 -0.025175 0.90821649 0.04718118 FALSE  
MSTRG.7198.4 ENSG00000204842 No_inf pgKDN_inf ATXN2 protein_coding   25.20063 27.92812 23.26889 1.044873 1.761937 -0.2632125 2.8970623 4.2753475 2.8527270 0.6463585 1.6478305 -0.5820221 0.10846667 0.154300 0.108925 -0.045375 0.73655897 0.04718118 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000204842 E001 5.8593196 0.0033595312 1.399175e-01 0.397875548 12 111443485 111444187 703 - 0.917 0.757 -0.621
ENSG00000204842 E002 0.0000000       12 111451122 111451190 69 -      
ENSG00000204842 E003 0.6240057 0.1956870667 3.615756e-01 0.651023500 12 111451947 111452085 139 - 0.107 0.269 1.620
ENSG00000204842 E004 0.2458395 0.0163742907 8.369512e-01   12 111452191 111452213 23 - 0.107 0.084 -0.380
ENSG00000204842 E005 0.2458395 0.0163742907 8.369512e-01   12 111452214 111452214 1 - 0.107 0.084 -0.380
ENSG00000204842 E006 0.3729758 0.1932206722 7.985545e-01   12 111452215 111452222 8 - 0.107 0.155 0.620
ENSG00000204842 E007 0.6347699 0.0275982653 4.328945e-02 0.202847344 12 111452223 111452260 38 - 0.000 0.317 13.069
ENSG00000204842 E008 0.6347699 0.0275982653 4.328945e-02 0.202847344 12 111452261 111452267 7 - 0.000 0.317 13.069
ENSG00000204842 E009 1.4862691 0.0182054199 4.871426e-01 0.750767589 12 111452268 111452290 23 - 0.326 0.434 0.620
ENSG00000204842 E010 3.4580504 0.0270232711 6.819905e-01 0.868345438 12 111452291 111452295 5 - 0.610 0.667 0.248
ENSG00000204842 E011 7.0516921 0.0069085213 3.344030e-01 0.626195822 12 111452296 111452413 118 - 0.837 0.941 0.398
ENSG00000204842 E012 1.7331061 0.0425517016 5.889737e-01 0.817752379 12 111452414 111452430 17 - 0.380 0.467 0.468
ENSG00000204842 E013 2.1055136 0.0422187947 5.296658e-01 0.781031191 12 111452431 111452444 14 - 0.427 0.526 0.494
ENSG00000204842 E014 1.9874746 0.0092651443 3.265472e-01 0.618943965 12 111452445 111452450 6 - 0.380 0.526 0.757
ENSG00000204842 E015 1.7264706 0.0080142792 9.659193e-01 0.993003311 12 111452451 111452462 12 - 0.427 0.434 0.035
ENSG00000204842 E016 3.5844870 0.0039236576 5.530519e-01 0.796313302 12 111452463 111452481 19 - 0.610 0.687 0.330
ENSG00000204842 E017 11.3253851 0.0012618799 9.896297e-01 1.000000000 12 111452482 111452528 47 - 1.085 1.085 -0.002
ENSG00000204842 E018 13.4158657 0.0143731281 9.245628e-01 0.977150746 12 111452529 111452564 36 - 1.159 1.149 -0.035
ENSG00000204842 E019 24.4144426 0.0008139016 4.742984e-01 0.741040394 12 111452565 111452682 118 - 1.373 1.417 0.150
ENSG00000204842 E020 15.1282452 0.0255310593 6.228838e-02 0.250649977 12 111452683 111452753 71 - 1.085 1.269 0.655
ENSG00000204842 E021 16.5337846 0.0009526821 4.644944e-01 0.733979299 12 111452754 111452840 87 - 1.206 1.259 0.187
ENSG00000204842 E022 4.4908428 0.0240309700 3.535319e-02 0.179982933 12 111452841 111453319 479 - 0.546 0.832 1.205
ENSG00000204842 E023 2.5174287 0.0269770708 1.802230e-03 0.023575423 12 111453320 111453485 166 - 0.193 0.687 2.790
ENSG00000204842 E024 2.0041275 0.1213328960 9.560006e-02 0.321933217 12 111453486 111453676 191 - 0.264 0.579 1.736
ENSG00000204842 E025 19.9985921 0.0324453261 3.517316e-01 0.641942259 12 111453677 111453845 169 - 1.263 1.351 0.310
ENSG00000204842 E026 10.6227883 0.0018487020 5.486759e-05 0.001442119 12 111453846 111455044 1199 - 0.800 1.181 1.416
ENSG00000204842 E027 2.0893439 0.0084152130 7.649006e-01 0.908513058 12 111455045 111455119 75 - 0.510 0.467 -0.210
ENSG00000204842 E028 7.7313413 0.0017909265 4.211956e-03 0.044024732 12 111455120 111455914 795 - 0.738 1.036 1.144
ENSG00000204842 E029 1.3706209 0.0165360559 2.782216e-01 0.571533174 12 111455915 111456028 114 - 0.264 0.434 1.035
ENSG00000204842 E030 11.7543922 0.0011423773 1.309245e-01 0.383806916 12 111456029 111456081 53 - 1.021 1.149 0.463
ENSG00000204842 E031 11.5685563 0.0012184006 9.690671e-01 0.993641226 12 111456082 111456136 55 - 1.095 1.092 -0.010
ENSG00000204842 E032 10.3031199 0.0015397187 3.220532e-01 0.615093253 12 111456137 111456188 52 - 1.095 1.010 -0.311
ENSG00000204842 E033 8.6493181 0.0017796236 4.147434e-01 0.694984532 12 111456189 111456220 32 - 0.931 1.010 0.291
ENSG00000204842 E034 8.6489476 0.0016819696 4.138097e-01 0.694349387 12 111456221 111456256 36 - 0.931 1.010 0.291
ENSG00000204842 E035 10.4896873 0.0014593247 5.267870e-01 0.778971960 12 111457214 111457273 60 - 1.021 1.077 0.205
ENSG00000204842 E036 12.0572124 0.0127053666 9.176593e-01 0.974066581 12 111457274 111457359 86 - 1.114 1.107 -0.025
ENSG00000204842 E037 3.3839401 0.0069704419 7.065140e-03 0.063455662 12 111457360 111458401 1042 - 0.380 0.757 1.757
ENSG00000204842 E038 1.4973483 0.0100986186 1.898524e-01 0.468755649 12 111461139 111461305 167 - 0.264 0.467 1.205
ENSG00000204842 E039 3.4596879 0.0384032259 6.665325e-01 0.861339079 12 111464662 111464715 54 - 0.610 0.667 0.247
ENSG00000204842 E040 5.4994629 0.0026300759 1.856328e-01 0.463471874 12 111468358 111469425 1068 - 0.887 0.741 -0.573
ENSG00000204842 E041 2.7106833 0.0078561583 8.151115e-01 0.932395521 12 111469426 111469817 392 - 0.546 0.579 0.151
ENSG00000204842 E042 1.3435838 0.0092390713 4.642763e-01 0.733844294 12 111469818 111470107 290 - 0.427 0.317 -0.643
ENSG00000204842 E043 14.8513158 0.0009448135 4.132701e-01 0.694068308 12 111470108 111470240 133 - 1.228 1.168 -0.213
ENSG00000204842 E044 19.9029277 0.0006729261 5.576633e-01 0.799495344 12 111470558 111470742 185 - 1.336 1.298 -0.130
ENSG00000204842 E045 1.0862264 0.0191877988 1.673702e-01 0.438060675 12 111470743 111471945 1203 - 0.427 0.216 -1.380
ENSG00000204842 E046 0.5923132 0.0150428970 9.336353e-03 0.076907523 12 111479070 111479102 33 - 0.380 0.000 -13.935
ENSG00000204842 E047 0.4998907 0.0153029739 4.634569e-01 0.733305004 12 111482787 111482831 45 - 0.107 0.216 1.205
ENSG00000204842 E048 0.0000000       12 111485109 111485264 156 -      
ENSG00000204842 E049 2.8586203 0.0078584145 2.087743e-01 0.492850247 12 111485265 111485270 6 - 0.471 0.647 0.813
ENSG00000204842 E050 10.2704722 0.0013414426 1.002741e-01 0.330783390 12 111485271 111485331 61 - 1.123 0.981 -0.518
ENSG00000204842 E051 14.8725848 0.0009991358 6.266914e-03 0.058281477 12 111485713 111485865 153 - 1.301 1.100 -0.713
ENSG00000204842 E052 8.8263155 0.0015538973 3.781428e-01 0.665266045 12 111486761 111486824 64 - 1.032 0.951 -0.300
ENSG00000204842 E053 11.7844943 0.0011122494 4.950314e-01 0.756347373 12 111488476 111488584 109 - 1.132 1.077 -0.199
ENSG00000204842 E054 14.0805989 0.0011075894 1.311297e-01 0.384164925 12 111488585 111488780 196 - 1.235 1.122 -0.405
ENSG00000204842 E055 6.9538233 0.0025094534 1.000599e-01 0.330522740 12 111509549 111509619 71 - 0.985 0.818 -0.634
ENSG00000204842 E056 6.4184101 0.0057780662 6.605947e-01 0.858311623 12 111509891 111509918 28 - 0.837 0.884 0.182
ENSG00000204842 E057 8.2864724 0.0164812569 3.476822e-01 0.638311612 12 111509919 111509998 80 - 0.902 1.001 0.368
ENSG00000204842 E058 5.6315366 0.0024922727 3.728431e-01 0.660588740 12 111510385 111510444 60 - 0.871 0.773 -0.380
ENSG00000204842 E059 8.3563958 0.0032030245 7.184764e-01 0.886715199 12 111510445 111510577 133 - 0.985 0.951 -0.125
ENSG00000204842 E060 2.2306684 0.5045722357 6.000694e-01 0.824793735 12 111510578 111510582 5 - 0.427 0.553 0.621
ENSG00000204842 E061 6.5199295 0.0023136075 6.962756e-05 0.001746141 12 111510583 111512107 1525 - 0.546 1.010 1.876
ENSG00000204842 E062 0.2457744 0.0163986117 8.368083e-01   12 111512473 111512566 94 - 0.107 0.084 -0.380
ENSG00000204842 E063 2.0087866 0.1721371835 1.161398e-01 0.359291129 12 111512567 111513356 790 - 0.264 0.579 1.735
ENSG00000204842 E064 7.7185970 0.0747594075 5.353476e-01 0.785137658 12 111513357 111513473 117 - 0.985 0.896 -0.333
ENSG00000204842 E065 6.5980908 0.1745319147 4.685034e-01 0.736619545 12 111513474 111513539 66 - 0.959 0.804 -0.594
ENSG00000204842 E066 11.1653256 0.0212550604 4.027099e-01 0.685793118 12 111516154 111516363 210 - 1.123 1.045 -0.285
ENSG00000204842 E067 0.0000000       12 111516364 111516399 36 -      
ENSG00000204842 E068 11.2697980 0.0028787994 6.034738e-05 0.001554334 12 111518249 111518427 179 - 1.249 0.907 -1.243
ENSG00000204842 E069 0.1268540 0.0123379847 7.021109e-01   12 111519832 111519878 47 - 0.000 0.084 10.747
ENSG00000204842 E070 4.8389056 0.2673970838 3.057009e-01 0.598965848 12 111519879 111519912 34 - 0.917 0.602 -1.272
ENSG00000204842 E071 7.8518099 0.0020329294 5.811007e-01 0.813367299 12 111519913 111520004 92 - 0.972 0.919 -0.199
ENSG00000204842 E072 4.4239004 0.0032340500 9.007248e-01 0.967877138 12 111520005 111520019 15 - 0.738 0.724 -0.058
ENSG00000204842 E073 6.0564374 0.0027645164 3.492627e-01 0.639630997 12 111520020 111520076 57 - 0.780 0.884 0.404
ENSG00000204842 E074 8.6031340 0.0034914037 8.817330e-01 0.960268700 12 111520882 111520973 92 - 0.985 0.972 -0.049
ENSG00000204842 E075 9.9030426 0.0015879737 1.299520e-01 0.382400383 12 111525192 111525316 125 - 1.105 0.972 -0.487
ENSG00000204842 E076 9.9650666 0.0015134125 9.705167e-01 0.994124912 12 111552280 111552430 151 - 1.032 1.036 0.014
ENSG00000204842 E077 0.2537694 0.0161197873 3.480021e-01   12 111552431 111552734 304 - 0.000 0.155 11.747
ENSG00000204842 E078 4.5097121 0.0261320230 1.499150e-01 0.412421150 12 111552906 111552977 72 - 0.837 0.647 -0.773
ENSG00000204842 E079 3.3831507 0.0934317708 5.007193e-02 0.220996690 12 111554158 111554217 60 - 0.800 0.467 -1.458
ENSG00000204842 E080 2.7891423 0.1515639705 3.397313e-01 0.631406155 12 111555883 111555919 37 - 0.691 0.467 -1.016
ENSG00000204842 E081 0.2459655 0.0164734706 8.374638e-01   12 111565217 111565251 35 - 0.107 0.084 -0.380
ENSG00000204842 E082 0.0000000       12 111597749 111597915 167 -      
ENSG00000204842 E083 0.8632050 0.0167107201 9.756534e-01 0.995748601 12 111597916 111598566 651 - 0.264 0.269 0.035
ENSG00000204842 E084 6.1867506 0.0043336824 6.543383e-03 0.060110850 12 111598784 111599574 791 - 0.997 0.706 -1.132
ENSG00000204842 E085 0.2447669 0.0168642813 8.358244e-01   12 111599575 111599676 102 - 0.107 0.084 -0.380

Help

Please Click HERE to learn more details about the results from DEXseq.