ENSG00000205250

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000379378 ENSG00000205250 No_inf pgKDN_inf E2F4 protein_coding protein_coding 64.72172 62.44595 64.86866 2.797535 0.889405 0.05490485 51.833900 43.622122 56.620442 1.7473813 0.8413716 0.3761871 0.80185000 0.704875 0.873250 0.168375 0.02569155 0.02569155 FALSE TRUE
ENST00000568693 ENSG00000205250 No_inf pgKDN_inf E2F4 protein_coding retained_intron 64.72172 62.44595 64.86866 2.797535 0.889405 0.05490485 3.535704 4.504107 1.987885 0.9600448 0.2430434 -1.1759668 0.05416667 0.070700 0.030725 -0.039975 0.40226556 0.02569155   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000205250 E001 0.3561095 0.5139585160 0.2878730390   16 67192155 67192173 19 + 0.239 0.000 -10.372
ENSG00000205250 E002 0.7100089 0.0181515332 0.0102254407 0.08148625 16 67192174 67192184 11 + 0.391 0.000 -14.216
ENSG00000205250 E003 0.8276395 0.0262125003 0.0052000665 0.05106708 16 67192185 67192189 5 + 0.432 0.000 -14.346
ENSG00000205250 E004 3.1267530 0.0059030145 0.0061675433 0.05760174 16 67192190 67192206 17 + 0.769 0.394 -1.724
ENSG00000205250 E005 3.2453911 0.0082551015 0.0041729815 0.04376149 16 67192207 67192207 1 + 0.787 0.394 -1.794
ENSG00000205250 E006 3.6085139 0.0126184533 0.0044972676 0.04600917 16 67192208 67192212 5 + 0.820 0.435 -1.703
ENSG00000205250 E007 4.4708980 0.0326838262 0.0309471385 0.16569787 16 67192213 67192214 2 + 0.865 0.569 -1.228
ENSG00000205250 E008 27.2120788 0.0005796460 0.0011666053 0.01684597 16 67192215 67192362 148 + 1.536 1.350 -0.642
ENSG00000205250 E009 1.3515774 0.0343321092 0.7590031330 0.90537871 16 67192363 67192494 132 + 0.346 0.394 0.276
ENSG00000205250 E010 0.8706000 0.0204404194 0.2498771206 0.54081450 16 67192495 67192526 32 + 0.172 0.348 1.335
ENSG00000205250 E011 1.0066778 0.0116619268 0.0251446104 0.14587259 16 67192527 67192664 138 + 0.095 0.435 2.821
ENSG00000205250 E012 0.6256424 0.0152270598 0.1680730002 0.43908206 16 67192665 67192760 96 + 0.095 0.297 2.013
ENSG00000205250 E013 23.9501910 0.0005876876 0.5430876052 0.79008677 16 67192761 67192824 64 + 1.417 1.378 -0.134
ENSG00000205250 E014 21.6116753 0.0006667295 0.3813044089 0.66774700 16 67192825 67192870 46 + 1.383 1.326 -0.199
ENSG00000205250 E015 9.3151299 0.0014193344 0.0005992323 0.01005701 16 67192871 67193008 138 + 0.820 1.139 1.190
ENSG00000205250 E016 60.8725497 0.0049797924 0.4472911524 0.72148222 16 67193009 67193170 162 + 1.810 1.773 -0.126
ENSG00000205250 E017 2.1040440 0.0065390925 0.2158327293 0.50177691 16 67193171 67193421 251 + 0.391 0.569 0.888
ENSG00000205250 E018 0.9895855 0.0114206432 0.4688695939 0.73697881 16 67193422 67193471 50 + 0.238 0.348 0.750
ENSG00000205250 E019 26.3822245 0.0031262529 0.2854405291 0.57912762 16 67193472 67193515 44 + 1.404 1.467 0.215
ENSG00000205250 E020 7.4578074 0.0019414831 0.0015325136 0.02081448 16 67193978 67194397 420 + 0.731 1.054 1.236
ENSG00000205250 E021 31.7459355 0.0006995171 0.5777804733 0.81131629 16 67194398 67194459 62 + 1.501 1.528 0.091
ENSG00000205250 E022 89.3439359 0.0002369012 0.2266453040 0.51488069 16 67194686 67194951 266 + 1.976 1.936 -0.133
ENSG00000205250 E023 23.4051450 0.0005683004 0.1027816419 0.33515266 16 67194952 67194980 29 + 1.436 1.336 -0.349
ENSG00000205250 E024 2.9568907 0.0046807193 0.3978327136 0.68187973 16 67195651 67195781 131 + 0.536 0.648 0.499
ENSG00000205250 E025 91.8067744 0.0002083184 0.1788953990 0.45388559 16 67195782 67196006 225 + 1.989 1.946 -0.144
ENSG00000205250 E026 0.1272623 0.0123507813 0.5303755507   16 67196007 67196008 2 + 0.000 0.095 10.929
ENSG00000205250 E027 44.8857842 0.0003596638 0.3747050982 0.66234087 16 67197599 67197646 48 + 1.642 1.679 0.124
ENSG00000205250 E028 49.8319256 0.0003283727 0.0045985872 0.04667972 16 67197867 67197911 45 + 1.642 1.758 0.393
ENSG00000205250 E029 0.6265888 0.0148521285 0.1681011920 0.43909191 16 67197912 67198007 96 + 0.095 0.297 2.013
ENSG00000205250 E030 76.3103219 0.0002352496 0.0133526574 0.09698581 16 67198008 67198130 123 + 1.845 1.925 0.270
ENSG00000205250 E031 215.1810396 0.0001233019 0.7393996813 0.89675451 16 67198131 67198918 788 + 2.333 2.336 0.012

Help

Please Click HERE to learn more details about the results from DEXseq.