ENSG00000211456

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000389061 ENSG00000211456 No_inf pgKDN_inf SACM1L protein_coding protein_coding 35.4804 36.68614 36.99696 1.322775 0.8477066 0.01216839 19.520958 12.643437 27.0993657 4.7182095 4.7913220 1.09926208 0.55670000 0.359225 0.729750 0.370525 0.57548282 0.04688295 FALSE TRUE
ENST00000441228 ENSG00000211456 No_inf pgKDN_inf SACM1L protein_coding nonsense_mediated_decay 35.4804 36.68614 36.99696 1.322775 0.8477066 0.01216839 6.048951 7.174781 6.7098419 1.7405072 4.2808583 -0.09651684 0.16875000 0.192375 0.185200 -0.007175 0.78219092 0.04688295 FALSE TRUE
ENST00000464102 ENSG00000211456 No_inf pgKDN_inf SACM1L protein_coding retained_intron 35.4804 36.68614 36.99696 1.322775 0.8477066 0.01216839 2.839657 5.970095 0.8703524 1.5303694 0.7184272 -2.76401537 0.07832500 0.160100 0.023625 -0.136475 0.04688295 0.04688295 FALSE TRUE
ENST00000471207 ENSG00000211456 No_inf pgKDN_inf SACM1L protein_coding retained_intron 35.4804 36.68614 36.99696 1.322775 0.8477066 0.01216839 2.778186 4.540893 1.3432542 0.5413787 0.5810002 -1.74971684 0.07801667 0.122975 0.035650 -0.087325 0.24364358 0.04688295   FALSE
ENST00000672858 ENSG00000211456 No_inf pgKDN_inf SACM1L protein_coding protein_coding 35.4804 36.68614 36.99696 1.322775 0.8477066 0.01216839 2.452578 4.477886 0.0000000 2.6089300 0.0000000 -8.80989225 0.06635000 0.115300 0.000000 -0.115300 0.48101214 0.04688295 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000211456 E001 0.0000000       3 45689056 45689134 79 +      
ENSG00000211456 E002 0.0000000       3 45689186 45689240 55 +      
ENSG00000211456 E003 0.0000000       3 45689241 45689261 21 +      
ENSG00000211456 E004 0.0000000       3 45689262 45689354 93 +      
ENSG00000211456 E005 0.0000000       3 45689355 45689355 1 +      
ENSG00000211456 E006 0.0000000       3 45689356 45689356 1 +      
ENSG00000211456 E007 0.3641952 0.0167657601 0.6384023403   3 45689357 45689395 39 + 0.167 0.099 -0.873
ENSG00000211456 E008 3.9916331 0.0039955966 0.0960535867 0.322783649 3 45689396 45689458 63 + 0.789 0.581 -0.873
ENSG00000211456 E009 4.5898028 0.0029956413 0.0441798250 0.205552788 3 45689459 45689465 7 + 0.851 0.610 -0.988
ENSG00000211456 E010 8.0859004 0.0070444931 0.0092676803 0.076565095 3 45689466 45689497 32 + 1.071 0.804 -1.004
ENSG00000211456 E011 0.0000000       3 45689498 45689545 48 +      
ENSG00000211456 E012 0.1265070 0.0122644461 0.4937422733   3 45689546 45690347 802 + 0.000 0.099 10.884
ENSG00000211456 E013 0.2340080 0.1937013864 0.3167388880   3 45690348 45690387 40 + 0.167 0.000 -11.885
ENSG00000211456 E014 14.8434746 0.0033647231 0.2004727365 0.482476420 3 45703438 45703535 98 + 1.246 1.148 -0.350
ENSG00000211456 E015 12.1106215 0.0443753305 0.7845151448 0.916838543 3 45705135 45705209 75 + 1.104 1.131 0.099
ENSG00000211456 E016 13.6495610 0.0492616306 0.6903003986 0.872811837 3 45706780 45706907 128 + 1.191 1.140 -0.182
ENSG00000211456 E017 1.9927077 0.1116911938 0.0698265329 0.267283480 3 45706908 45707318 411 + 0.287 0.610 1.713
ENSG00000211456 E018 18.3259559 0.0008082585 0.0127832473 0.094205682 3 45709498 45709647 150 + 1.362 1.193 -0.595
ENSG00000211456 E019 0.0000000       3 45709648 45709648 1 +      
ENSG00000211456 E020 7.1788514 0.0021579640 0.2746846983 0.568152015 3 45713137 45713140 4 + 0.964 0.854 -0.417
ENSG00000211456 E021 9.7204008 0.0015199652 0.1047635486 0.338382097 3 45713141 45713195 55 + 1.096 0.951 -0.534
ENSG00000211456 E022 2.9053326 0.0272286488 0.1809328442 0.456727138 3 45713196 45713196 1 + 0.677 0.484 -0.873
ENSG00000211456 E023 0.9978927 0.0203453428 0.1242494900 0.373478640 3 45713197 45714045 849 + 0.167 0.404 1.712
ENSG00000211456 E024 6.1779532 0.0120371865 0.0895876414 0.311048014 3 45714046 45714079 34 + 0.941 0.748 -0.748
ENSG00000211456 E025 0.1187032 0.0117835536 0.5860261231   3 45714080 45714082 3 + 0.091 0.000 -11.580
ENSG00000211456 E026 16.8162139 0.0008797499 0.2326786159 0.521304590 3 45719500 45719601 102 + 1.290 1.207 -0.294
ENSG00000211456 E027 16.8737234 0.0044741883 0.8731619707 0.956705125 3 45722000 45722085 86 + 1.258 1.246 -0.041
ENSG00000211456 E028 17.2849495 0.0008063585 0.3500179006 0.640209769 3 45722869 45722955 87 + 1.229 1.294 0.229
ENSG00000211456 E029 13.5343357 0.0011416533 0.5594972677 0.800549099 3 45723475 45723543 69 + 1.184 1.140 -0.160
ENSG00000211456 E030 0.1268540 0.0122595106 0.4937233564   3 45730603 45730670 68 + 0.000 0.099 10.884
ENSG00000211456 E031 15.5874866 0.0016983573 0.2773762729 0.570731417 3 45731301 45731380 80 + 1.258 1.178 -0.281
ENSG00000211456 E032 17.2715740 0.0008805710 0.5505932714 0.794845761 3 45732053 45732151 99 + 1.240 1.282 0.147
ENSG00000211456 E033 4.3967873 0.0775517536 0.0002527871 0.005066450 3 45734595 45735234 640 + 0.337 0.938 2.712
ENSG00000211456 E034 8.2337059 0.0018493940 0.2304061121 0.518979498 3 45735235 45735245 11 + 0.905 1.020 0.430
ENSG00000211456 E035 24.3033102 0.0005654669 0.6503394867 0.852773088 3 45735246 45735373 128 + 1.416 1.390 -0.091
ENSG00000211456 E036 4.7501171 0.0039125735 0.0001013428 0.002400448 3 45737244 45737582 339 + 0.458 0.938 2.034
ENSG00000211456 E037 16.1987849 0.0117019936 0.3111920599 0.604408965 3 45737583 45737652 70 + 1.274 1.193 -0.288
ENSG00000211456 E038 0.1268540 0.0122595106 0.4937233564   3 45737762 45737771 10 + 0.000 0.099 10.884
ENSG00000211456 E039 21.7462656 0.0060861966 0.0464916239 0.211619482 3 45737772 45737844 73 + 1.420 1.282 -0.478
ENSG00000211456 E040 38.0095807 0.0006474001 0.9765685305 0.996146445 3 45738578 45738671 94 + 1.590 1.592 0.006
ENSG00000211456 E041 36.3467366 0.0003993547 0.5620178162 0.802113493 3 45738781 45738873 93 + 1.558 1.587 0.098
ENSG00000211456 E042 26.0657381 0.0047415269 0.1536571406 0.418468199 3 45739587 45739644 58 + 1.474 1.385 -0.308
ENSG00000211456 E043 0.6170207 0.0157095635 0.5890018668 0.817752379 3 45739645 45739907 263 + 0.167 0.247 0.712
ENSG00000211456 E044 377.2465595 0.0001395226 0.0005662902 0.009628718 3 45743533 45745409 1877 + 2.558 2.597 0.133

Help

Please Click HERE to learn more details about the results from DEXseq.