ENSG00000213339

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000250237 ENSG00000213339 No_inf pgKDN_inf QTRT1 protein_coding protein_coding 25.16908 21.44644 21.50734 0.9568791 0.5197248 0.004088482 11.9680480 7.761140 14.6825179 0.8891504 0.9972167 0.9188834 0.49010000 0.368150 0.681325 0.313175 0.01864903 0.01864903 FALSE TRUE
ENST00000421333 ENSG00000213339 No_inf pgKDN_inf QTRT1 protein_coding nonsense_mediated_decay 25.16908 21.44644 21.50734 0.9568791 0.5197248 0.004088482 0.8077093 1.865669 0.0000000 0.7860735 0.0000000 -7.5512615 0.03376667 0.082700 0.000000 -0.082700 0.05743506 0.01864903 TRUE TRUE
ENST00000587500 ENSG00000213339 No_inf pgKDN_inf QTRT1 protein_coding retained_intron 25.16908 21.44644 21.50734 0.9568791 0.5197248 0.004088482 2.3494286 1.891984 0.7578711 0.8339892 0.4377956 -1.3085693 0.08500833 0.084425 0.034175 -0.050250 0.79411619 0.01864903 FALSE FALSE
ENST00000589488 ENSG00000213339 No_inf pgKDN_inf QTRT1 protein_coding retained_intron 25.16908 21.44644 21.50734 0.9568791 0.5197248 0.004088482 5.2002671 5.939193 3.3978200 0.4747023 0.8475665 -0.8038447 0.21229167 0.280425 0.160725 -0.119700 0.54463473 0.01864903 TRUE TRUE
ENST00000590705 ENSG00000213339 No_inf pgKDN_inf QTRT1 protein_coding retained_intron 25.16908 21.44644 21.50734 0.9568791 0.5197248 0.004088482 1.8091226 1.398645 1.0712076 0.8231851 0.1145886 -0.3816650 0.06695833 0.065525 0.049900 -0.015625 0.87788578 0.01864903 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000213339 E001 0.1176306 0.0117412427 0.514429894   19 10701430 10701438 9 + 0.098 0.000 -10.941
ENSG00000213339 E002 1.0797097 0.0114472485 0.077766255 0.28536163 19 10701439 10701453 15 + 0.442 0.169 -1.894
ENSG00000213339 E003 2.7776075 0.0051756178 0.046265577 0.21094663 19 10701454 10701465 12 + 0.702 0.425 -1.279
ENSG00000213339 E004 3.3846496 0.0041747469 0.043839937 0.20449177 19 10701466 10701470 5 + 0.763 0.497 -1.164
ENSG00000213339 E005 19.7478192 0.0007351612 0.782395984 0.91627473 19 10701471 10701703 233 + 1.310 1.321 0.039
ENSG00000213339 E006 12.0683718 0.0012600079 0.156586561 0.42292614 19 10701950 10702018 69 + 1.055 1.163 0.389
ENSG00000213339 E007 1.2246931 0.0228904163 0.943941620 0.98448572 19 10702019 10702115 97 + 0.354 0.340 -0.086
ENSG00000213339 E008 12.2534003 0.0012031175 0.005927871 0.05601153 19 10702116 10702160 45 + 0.992 1.210 0.784
ENSG00000213339 E009 18.2025227 0.0010706240 0.215145026 0.50086899 19 10702161 10702254 94 + 1.240 1.316 0.266
ENSG00000213339 E010 0.7246144 0.0150594725 0.383497516 0.66959130 19 10706710 10706825 116 + 0.303 0.169 -1.086
ENSG00000213339 E011 8.6612737 0.0489638725 0.425018397 0.70415133 19 10707302 10707305 4 + 1.035 0.935 -0.371
ENSG00000213339 E012 16.6150934 0.0244643334 0.464105412 0.73367899 19 10707306 10707380 75 + 1.282 1.210 -0.256
ENSG00000213339 E013 1.0075244 0.0118463003 0.030667170 0.16473971 19 10707466 10707499 34 + 0.098 0.425 2.721
ENSG00000213339 E014 17.8718793 0.0020893754 0.659347911 0.85784895 19 10707500 10707615 116 + 1.294 1.258 -0.126
ENSG00000213339 E015 0.4787723 0.0212028050 0.299437073   19 10708951 10709138 188 + 0.245 0.093 -1.671
ENSG00000213339 E016 0.1271363 0.0122802318 0.562584848   19 10709281 10709364 84 + 0.000 0.093 10.664
ENSG00000213339 E017 4.4187172 0.0034187199 0.841994449 0.94329543 19 10711040 10712160 1121 + 0.723 0.741 0.074
ENSG00000213339 E018 19.1508563 0.0215486118 0.157699026 0.42437577 19 10712161 10712299 139 + 1.365 1.240 -0.437
ENSG00000213339 E019 10.7901942 0.0013272102 0.001442934 0.01982757 19 10712300 10712552 253 + 0.906 1.177 0.989
ENSG00000213339 E020 8.1770320 0.0145767680 0.342117854 0.63351591 19 10712553 10712562 10 + 1.014 0.910 -0.389
ENSG00000213339 E021 13.1881570 0.0011036808 0.308416075 0.60162324 19 10712563 10712628 66 + 1.194 1.110 -0.300
ENSG00000213339 E022 0.8719851 0.0131800096 0.278948097 0.57217486 19 10712663 10712757 95 + 0.177 0.340 1.236
ENSG00000213339 E023 20.3067124 0.0006786754 0.535684100 0.78532531 19 10712758 10712867 110 + 1.351 1.306 -0.156
ENSG00000213339 E024 0.0000000       19 10712918 10712952 35 +      
ENSG00000213339 E025 16.7004741 0.0008899022 0.541838655 0.78935784 19 10712953 10713040 88 + 1.228 1.263 0.126
ENSG00000213339 E026 5.7807649 0.0023789104 0.564968264 0.80403807 19 10713118 10713123 6 + 0.799 0.856 0.222
ENSG00000213339 E027 8.4664308 0.0017150136 0.860281674 0.95157920 19 10713124 10713197 74 + 0.970 0.980 0.039
ENSG00000213339 E028 5.3658097 0.0027269162 0.453726019 0.72640513 19 10713198 10713365 168 + 0.848 0.760 -0.349
ENSG00000213339 E029 0.1186381 0.0117842378 0.514506525   19 10713369 10713437 69 + 0.098 0.000 -10.942

Help

Please Click HERE to learn more details about the results from DEXseq.