ENSG00000215375

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000400159 ENSG00000215375 No_inf pgKDN_inf MYL5 protein_coding protein_coding 35.55402 59.97323 18.41944 20.84755 0.8268248 -1.702547 2.418188 2.989001 0.5886755 1.2513017 0.3754414 -2.3246357 0.07201667 0.051800 0.032850 -0.018950 0.86437910 0.01607353 FALSE TRUE
ENST00000502720 ENSG00000215375 No_inf pgKDN_inf MYL5 protein_coding retained_intron 35.55402 59.97323 18.41944 20.84755 0.8268248 -1.702547 3.613378 6.882519 1.2804054 0.7228724 0.7521101 -2.4172071 0.10420000 0.149500 0.070425 -0.079075 0.58676194 0.01607353 FALSE FALSE
ENST00000503612 ENSG00000215375 No_inf pgKDN_inf MYL5 protein_coding retained_intron 35.55402 59.97323 18.41944 20.84755 0.8268248 -1.702547 2.340105 4.209158 0.7913162 0.4427618 0.3158622 -2.3965116 0.06845000 0.092575 0.040850 -0.051725 0.68827008 0.01607353   FALSE
ENST00000505477 ENSG00000215375 No_inf pgKDN_inf MYL5 protein_coding protein_coding 35.55402 59.97323 18.41944 20.84755 0.8268248 -1.702547 4.356131 6.877405 0.0000000 4.0438819 0.0000000 -9.4278166 0.12540000 0.168425 0.000000 -0.168425 0.84158044 0.01607353 FALSE TRUE
ENST00000507804 ENSG00000215375 No_inf pgKDN_inf MYL5 protein_coding protein_coding 35.55402 59.97323 18.41944 20.84755 0.8268248 -1.702547 3.168749 4.723722 0.8098318 0.6784801 0.3711441 -2.5295752 0.09175000 0.092000 0.043550 -0.048450 0.59487927 0.01607353 FALSE FALSE
MSTRG.21409.13 ENSG00000215375 No_inf pgKDN_inf MYL5 protein_coding   35.55402 59.97323 18.41944 20.84755 0.8268248 -1.702547 7.020653 21.061959 0.0000000 21.0619587 0.0000000 -11.0411087 0.05745833 0.172375 0.000000 -0.172375 1.00000000 0.01607353   FALSE
MSTRG.21409.4 ENSG00000215375 No_inf pgKDN_inf MYL5 protein_coding   35.55402 59.97323 18.41944 20.84755 0.8268248 -1.702547 7.924267 6.891394 12.4034783 3.1288714 1.1189152 0.8469478 0.32770000 0.137925 0.673525 0.535600 0.01607353 0.01607353 FALSE TRUE
MSTRG.21409.5 ENSG00000215375 No_inf pgKDN_inf MYL5 protein_coding   35.55402 59.97323 18.41944 20.84755 0.8268248 -1.702547 3.250218 4.454715 1.6515461 0.5172331 0.2164568 -1.4260418 0.10477500 0.094375 0.090175 -0.004200 1.00000000 0.01607353 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000215375 E001 0.0000000       4 673580 673940 361 +      
ENSG00000215375 E002 0.0000000       4 673941 673977 37 +      
ENSG00000215375 E003 0.8679277 0.1557962406 0.821315275 0.93512388 4 673978 674502 525 + 0.232 0.267 0.272
ENSG00000215375 E004 1.6332933 0.0125706497 0.163966163 0.43309423 4 674503 674541 39 + 0.232 0.458 1.409
ENSG00000215375 E005 2.8498321 0.0856312602 0.827332283 0.93748218 4 674542 674559 18 + 0.582 0.550 -0.145
ENSG00000215375 E006 9.4820292 0.0121847956 0.073651754 0.27622096 4 674560 674683 124 + 1.101 0.929 -0.636
ENSG00000215375 E007 3.0970957 0.1007462653 0.930154233 0.97949779 4 674684 674787 104 + 0.582 0.590 0.037
ENSG00000215375 E008 15.4008766 0.0009793293 0.648151801 0.85142528 4 674788 675453 666 + 1.158 1.194 0.128
ENSG00000215375 E009 10.8431770 0.0394506400 0.263578014 0.55666092 4 675454 675854 401 + 0.942 1.081 0.513
ENSG00000215375 E010 6.1313449 0.0022713011 0.058275496 0.24167863 4 675855 676072 218 + 0.655 0.883 0.913
ENSG00000215375 E011 15.1955969 0.0137560043 0.217590704 0.50408217 4 676073 676209 137 + 1.244 1.144 -0.357
ENSG00000215375 E012 2.6488183 0.0061021710 0.013160626 0.09610143 4 676210 676481 272 + 0.232 0.626 2.197
ENSG00000215375 E013 2.2306145 0.0080918706 0.937872666 0.98211507 4 677922 677953 32 + 0.493 0.483 -0.051
ENSG00000215375 E014 2.6185422 0.0485436425 0.441030430 0.71664534 4 677954 678029 76 + 0.441 0.571 0.627
ENSG00000215375 E015 7.5360196 0.0023100239 0.001813576 0.02368363 4 678189 678657 469 + 0.620 0.986 1.452
ENSG00000215375 E016 7.2637919 0.0019193729 0.109209710 0.34693211 4 678658 678665 8 + 0.992 0.831 -0.607
ENSG00000215375 E017 17.1914467 0.0008651382 0.365814983 0.65430342 4 678666 678765 100 + 1.270 1.208 -0.219
ENSG00000215375 E018 15.5953655 0.0010598079 0.550866182 0.79490744 4 678958 679033 76 + 1.217 1.174 -0.153
ENSG00000215375 E019 0.6249819 0.0152255107 0.558886179 0.80030730 4 679034 679173 140 + 0.131 0.225 0.949
ENSG00000215375 E020 18.9062294 0.0007631161 0.191698956 0.47141581 4 679914 680018 105 + 1.324 1.239 -0.299
ENSG00000215375 E021 15.3604281 0.0010494716 0.590424720 0.81868571 4 680509 680587 79 + 1.208 1.170 -0.137
ENSG00000215375 E022 4.2416001 0.0039349648 0.250310857 0.54139661 4 680746 681091 346 + 0.582 0.734 0.650
ENSG00000215375 E023 5.9816720 0.0028167063 0.416428785 0.69629433 4 681092 681140 49 + 0.747 0.842 0.378
ENSG00000215375 E024 1.8482909 0.0240225023 0.554522652 0.79728623 4 681293 681321 29 + 0.493 0.403 -0.466
ENSG00000215375 E025 0.0000000       4 681893 682028 136 +      

Help

Please Click HERE to learn more details about the results from DEXseq.