ENSG00000221968

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000278829 ENSG00000221968 No_inf pgKDN_inf FADS3 protein_coding protein_coding 42.4745 27.38949 44.13449 1.487061 2.600266 0.6880845 22.3723931 7.659881 26.557075 0.7487905 1.1635680 1.7923633 0.4921667 0.280375 0.603750 0.323375 4.088677e-05 4.088677e-05 FALSE TRUE
ENST00000526294 ENSG00000221968 No_inf pgKDN_inf FADS3 protein_coding retained_intron 42.4745 27.38949 44.13449 1.487061 2.600266 0.6880845 2.3202709 1.295946 2.716608 0.7568642 1.6165453 1.0620119 0.0524250 0.045825 0.058675 0.012850 1.000000e+00 4.088677e-05 FALSE FALSE
ENST00000527379 ENSG00000221968 No_inf pgKDN_inf FADS3 protein_coding protein_coding 42.4745 27.38949 44.13449 1.487061 2.600266 0.6880845 4.7500309 3.960361 2.619436 1.3522440 2.6194364 -0.5945165 0.1079583 0.140375 0.050800 -0.089575 2.996948e-01 4.088677e-05 FALSE TRUE
ENST00000527697 ENSG00000221968 No_inf pgKDN_inf FADS3 protein_coding protein_coding 42.4745 27.38949 44.13449 1.487061 2.600266 0.6880845 0.7880282 0.000000 2.364085 0.0000000 1.5945796 7.8912275 0.0189500 0.000000 0.056850 0.056850 5.756529e-01 4.088677e-05 FALSE TRUE
MSTRG.4812.6 ENSG00000221968 No_inf pgKDN_inf FADS3 protein_coding   42.4745 27.38949 44.13449 1.487061 2.600266 0.6880845 10.3527491 12.988757 7.175484 0.4445026 0.8517984 -0.8552164 0.2793917 0.477575 0.166550 -0.311025 5.414924e-04 4.088677e-05 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000221968 E001 0.0000000       11 61873519 61873523 5 -      
ENSG00000221968 E002 0.0000000       11 61873524 61873525 2 -      
ENSG00000221968 E003 0.3538994 0.0214512057 1.704929e-01   11 61873526 61873526 1 - 0.214 0.000 -10.921
ENSG00000221968 E004 0.4811617 0.0168429045 4.727377e-01   11 61873527 61873529 3 - 0.214 0.108 -1.182
ENSG00000221968 E005 0.8361987 0.0145813710 1.067394e-01 3.423049e-01 11 61873530 61873538 9 - 0.357 0.108 -2.182
ENSG00000221968 E006 25.6434516 0.0173313531 3.841039e-01 6.701905e-01 11 61873539 61873734 196 - 1.454 1.382 -0.252
ENSG00000221968 E007 12.8092304 0.0291940732 7.363459e-01 8.953486e-01 11 61873735 61873759 25 - 1.125 1.153 0.099
ENSG00000221968 E008 21.6097162 0.0105886515 5.150774e-01 7.713289e-01 11 61873760 61873813 54 - 1.331 1.376 0.157
ENSG00000221968 E009 23.4914841 0.0222067047 2.845525e-01 5.782396e-01 11 61873814 61873865 52 - 1.348 1.430 0.282
ENSG00000221968 E010 43.6131730 0.0003685741 8.123803e-01 9.309844e-01 11 61875851 61875976 126 - 1.652 1.641 -0.036
ENSG00000221968 E011 0.2444846 0.0161030149 8.279335e-01   11 61875977 61876003 27 - 0.084 0.108 0.403
ENSG00000221968 E012 0.1186381 0.0117413921 7.104986e-01   11 61876105 61876110 6 - 0.084 0.000 -9.336
ENSG00000221968 E013 35.2544140 0.0004550168 6.688810e-01 8.622028e-01 11 61876111 61876190 80 - 1.547 1.568 0.072
ENSG00000221968 E014 21.0987358 0.0016037330 8.219336e-01 9.354072e-01 11 61876359 61876370 12 - 1.335 1.350 0.050
ENSG00000221968 E015 34.6922616 0.0005219000 7.386774e-01 8.964012e-01 11 61876371 61876455 85 - 1.558 1.541 -0.057
ENSG00000221968 E016 30.1064523 0.0011876573 4.333807e-13 5.932476e-11 11 61876456 61876865 410 - 1.266 1.666 1.376
ENSG00000221968 E017 15.7715221 0.0008642344 2.123309e-01 4.975823e-01 11 61876866 61876877 12 - 1.261 1.170 -0.323
ENSG00000221968 E018 19.4500836 0.0007753255 5.307541e-01 7.816323e-01 11 61876878 61876911 34 - 1.327 1.285 -0.145
ENSG00000221968 E019 23.0524578 0.0006183115 1.075931e-01 3.439381e-01 11 61876912 61876963 52 - 1.421 1.322 -0.343
ENSG00000221968 E020 5.5677161 0.0301630875 1.157236e-02 8.852357e-02 11 61876964 61877445 482 - 0.644 0.962 1.261
ENSG00000221968 E021 1.7345593 0.0215983471 1.233016e-01 3.717127e-01 11 61877446 61877510 65 - 0.315 0.548 1.251
ENSG00000221968 E022 26.5968802 0.0005522264 1.962162e-01 4.768695e-01 11 61877511 61877583 73 - 1.470 1.397 -0.254
ENSG00000221968 E023 13.5041533 0.0010467766 7.289934e-01 8.919441e-01 11 61877584 61877587 4 - 1.171 1.144 -0.096
ENSG00000221968 E024 1.6244194 0.0326223253 1.780080e-02 1.174539e-01 11 61877588 61878154 567 - 0.214 0.581 2.140
ENSG00000221968 E025 26.1810155 0.0012084842 8.240121e-01 9.361565e-01 11 61878155 61878215 61 - 1.438 1.425 -0.044
ENSG00000221968 E026 34.8341243 0.0005064020 7.013054e-01 8.783159e-01 11 61878512 61878634 123 - 1.560 1.541 -0.066
ENSG00000221968 E027 0.2372762 0.2473198791 4.121455e-01   11 61878641 61878745 105 - 0.154 0.000 -10.337
ENSG00000221968 E028 27.1669565 0.0005434747 6.405781e-02 2.549244e-01 11 61878746 61878847 102 - 1.492 1.387 -0.362
ENSG00000221968 E029 23.6938903 0.0215916825 4.872681e-01 7.508288e-01 11 61879312 61879395 84 - 1.413 1.361 -0.182
ENSG00000221968 E030 26.1152494 0.0042966114 3.201487e-01 6.129645e-01 11 61879396 61879509 114 - 1.457 1.397 -0.210
ENSG00000221968 E031 21.2556879 0.0008106942 3.263731e-01 6.188499e-01 11 61880041 61880151 111 - 1.372 1.310 -0.217
ENSG00000221968 E032 0.0000000       11 61880152 61880380 229 -      
ENSG00000221968 E033 1.1152101 0.0122931230 1.594103e-01 4.268105e-01 11 61880381 61882526 2146 - 0.214 0.430 1.403
ENSG00000221968 E034 0.0000000       11 61886256 61886331 76 -      
ENSG00000221968 E035 0.0000000       11 61890213 61890403 191 -      
ENSG00000221968 E036 25.5265773 0.0223843405 5.012185e-01 7.612920e-01 11 61891169 61891603 435 - 1.444 1.392 -0.182
ENSG00000221968 E037 0.0000000       11 61891859 61892051 193 -      

Help

Please Click HERE to learn more details about the results from DEXseq.