ENSG00000223959

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000421164 ENSG00000223959 No_inf pgKDN_inf AFG3L1P transcribed_unitary_pseudogene retained_intron 11.4688 14.43999 9.861811 1.09361 0.6911898 -0.5496816 0.6929196 0.9220993 0.7429500 0.3199506 0.1594887 -0.3079297 0.06448333 0.069175 0.078975 0.009800 0.97002992 0.04050373 FALSE TRUE
ENST00000423684 ENSG00000223959 No_inf pgKDN_inf AFG3L1P transcribed_unitary_pseudogene retained_intron 11.4688 14.43999 9.861811 1.09361 0.6911898 -0.5496816 0.9874620 1.4168234 1.5455626 0.8416871 0.6129327 0.1246296 0.08382500 0.100250 0.151225 0.050975 0.83428937 0.04050373 FALSE TRUE
ENST00000429663 ENSG00000223959 No_inf pgKDN_inf AFG3L1P transcribed_unitary_pseudogene processed_transcript 11.4688 14.43999 9.861811 1.09361 0.6911898 -0.5496816 0.5443523 1.3032319 0.0000000 1.3032319 0.0000000 -7.0369779 0.04063333 0.085150 0.000000 -0.085150 0.89776030 0.04050373 TRUE TRUE
ENST00000437774 ENSG00000223959 No_inf pgKDN_inf AFG3L1P transcribed_unitary_pseudogene processed_transcript 11.4688 14.43999 9.861811 1.09361 0.6911898 -0.5496816 0.6249279 1.3972032 0.4775804 0.8611170 0.4775804 -1.5291188 0.04480833 0.092450 0.041975 -0.050475 0.84005108 0.04050373 FALSE FALSE
ENST00000450026 ENSG00000223959 No_inf pgKDN_inf AFG3L1P transcribed_unitary_pseudogene retained_intron 11.4688 14.43999 9.861811 1.09361 0.6911898 -0.5496816 0.9737140 1.6701980 0.5407940 0.6598949 0.3188712 -1.6090464 0.08028333 0.108650 0.054325 -0.054325 0.83308949 0.04050373 FALSE FALSE
ENST00000688932 ENSG00000223959 No_inf pgKDN_inf AFG3L1P transcribed_unitary_pseudogene processed_transcript 11.4688 14.43999 9.861811 1.09361 0.6911898 -0.5496816 0.5296847 0.0000000 0.5791508 0.0000000 0.5791508 5.8805651 0.05600000 0.000000 0.071850 0.071850 0.83058439 0.04050373 TRUE FALSE
ENST00000690928 ENSG00000223959 No_inf pgKDN_inf AFG3L1P transcribed_unitary_pseudogene processed_transcript 11.4688 14.43999 9.861811 1.09361 0.6911898 -0.5496816 0.6950692 0.0000000 2.0852077 0.0000000 0.8920749 7.7109495 0.07605833 0.000000 0.228175 0.228175 0.04050373 0.04050373 FALSE FALSE
MSTRG.11757.11 ENSG00000223959 No_inf pgKDN_inf AFG3L1P transcribed_unitary_pseudogene   11.4688 14.43999 9.861811 1.09361 0.6911898 -0.5496816 1.5514991 0.5898551 1.8449271 0.5898551 1.0670111 1.6286765 0.15795000 0.046250 0.175300 0.129050 0.73433300 0.04050373 TRUE FALSE
MSTRG.11757.21 ENSG00000223959 No_inf pgKDN_inf AFG3L1P transcribed_unitary_pseudogene   11.4688 14.43999 9.861811 1.09361 0.6911898 -0.5496816 0.9632836 1.6058188 0.4394746 1.0392287 0.4394746 -1.8459538 0.08357500 0.126500 0.042775 -0.083725 0.84012718 0.04050373 FALSE FALSE
MSTRG.11757.24 ENSG00000223959 No_inf pgKDN_inf AFG3L1P transcribed_unitary_pseudogene   11.4688 14.43999 9.861811 1.09361 0.6911898 -0.5496816 0.9228174 1.6422550 0.3436696 1.1693232 0.2478057 -2.2239621 0.07431667 0.099925 0.030975 -0.068950 0.82947847 0.04050373   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000223959 E001 0.0000000       16 89972581 89972585 5 +      
ENSG00000223959 E002 0.0000000       16 89972586 89972588 3 +      
ENSG00000223959 E003 0.0000000       16 89972589 89972592 4 +      
ENSG00000223959 E004 0.0000000       16 89972593 89972593 1 +      
ENSG00000223959 E005 0.1176306 0.0118076664 0.382176129   16 89972594 89972613 20 + 0.110 0.000 -10.984
ENSG00000223959 E006 0.2362687 0.0157809748 0.147605634   16 89972614 89972615 2 + 0.197 0.000 -14.565
ENSG00000223959 E007 0.2362687 0.0157809748 0.147605634   16 89972616 89972616 1 + 0.197 0.000 -14.565
ENSG00000223959 E008 0.8353810 0.0126618495 0.016981780 0.11377581 16 89972617 89972630 14 + 0.435 0.082 -3.045
ENSG00000223959 E009 0.9626433 0.0117935678 0.058164124 0.24140201 16 89972631 89972647 17 + 0.435 0.151 -2.045
ENSG00000223959 E010 2.0767872 0.0074874692 0.357618964 0.64720866 16 89972648 89972765 118 + 0.554 0.426 -0.630
ENSG00000223959 E011 0.6337937 0.1125828495 0.066153376 0.25900012 16 89977605 89977638 34 + 0.000 0.310 14.059
ENSG00000223959 E012 2.4578200 0.0058967208 0.768512945 0.91051984 16 89977639 89977677 39 + 0.554 0.518 -0.171
ENSG00000223959 E013 2.6957879 0.0058375791 0.437292773 0.71357099 16 89977678 89977693 16 + 0.619 0.518 -0.460
ENSG00000223959 E014 5.4976336 0.0025348247 0.116020906 0.35918200 16 89977694 89977802 109 + 0.897 0.731 -0.653
ENSG00000223959 E015 5.7297371 0.0514216580 0.072924816 0.27439145 16 89977803 89978517 715 + 0.648 0.908 1.043
ENSG00000223959 E016 3.1863016 0.0280529554 0.437325376 0.71358101 16 89978810 89978878 69 + 0.675 0.570 -0.460
ENSG00000223959 E017 1.3658321 0.3779361626 0.648636050 0.85169901 16 89979302 89979714 413 + 0.270 0.426 0.955
ENSG00000223959 E018 1.1070928 0.0122316241 0.869495509 0.95513414 16 89979715 89979890 176 + 0.332 0.310 -0.138
ENSG00000223959 E019 2.1944500 0.0066094516 0.242177824 0.53189234 16 89979891 89980241 351 + 0.588 0.426 -0.782
ENSG00000223959 E020 2.2222424 0.0165052199 0.807418773 0.92891050 16 89980242 89980244 3 + 0.479 0.518 0.192
ENSG00000223959 E021 5.0501428 0.0031165486 0.971881565 0.99471128 16 89980245 89980336 92 + 0.769 0.779 0.037
ENSG00000223959 E022 9.6881644 0.0016372023 0.244885107 0.53524207 16 89981773 89981918 146 + 1.076 0.980 -0.350
ENSG00000223959 E023 4.5366299 0.0075920126 0.404195197 0.68702101 16 89981919 89981923 5 + 0.790 0.696 -0.382
ENSG00000223959 E024 5.5158877 0.0066732985 0.339045911 0.63070749 16 89984531 89984599 69 + 0.864 0.763 -0.396
ENSG00000223959 E025 0.7446577 0.0142188331 0.674800975 0.86528085 16 89984600 89984617 18 + 0.197 0.264 0.540
ENSG00000223959 E026 1.5977028 0.0086432109 0.750179815 0.90145751 16 89984618 89984648 31 + 0.435 0.391 -0.238
ENSG00000223959 E027 3.0955558 0.0399631697 0.592077958 0.81991489 16 89984649 89984939 291 + 0.554 0.637 0.370
ENSG00000223959 E028 2.1045820 0.0345947782 0.608388964 0.82948709 16 89985193 89985396 204 + 0.435 0.518 0.414
ENSG00000223959 E029 0.8618876 0.0155497315 0.952539481 0.98825170 16 89985397 89985445 49 + 0.270 0.264 -0.045
ENSG00000223959 E030 2.7255643 0.0644868809 0.431103214 0.70875032 16 89985446 89985570 125 + 0.478 0.616 0.640
ENSG00000223959 E031 1.9867869 0.0075362942 0.392240775 0.67727434 16 89988496 89988681 186 + 0.387 0.518 0.677
ENSG00000223959 E032 2.2319022 0.0066413299 0.468440642 0.73660509 16 89988682 89988851 170 + 0.435 0.545 0.540
ENSG00000223959 E033 4.9797619 0.0778778818 0.050335746 0.22170748 16 89988852 89988951 100 + 0.913 0.637 -1.104
ENSG00000223959 E034 0.7618113 0.0139066613 0.026211582 0.14983524 16 89990332 89990865 534 + 0.000 0.353 14.369
ENSG00000223959 E035 5.6159560 0.0026915927 0.084173556 0.29959853 16 89990866 89991003 138 + 0.913 0.731 -0.712
ENSG00000223959 E036 0.7616885 0.3039600230 0.077947988 0.28560100 16 89991229 89991383 155 + 0.000 0.353 14.113
ENSG00000223959 E037 1.0058902 0.0120090646 0.073945997 0.27703552 16 89992551 89992720 170 + 0.110 0.391 2.347
ENSG00000223959 E038 5.0300945 0.0029950803 0.550254556 0.79475244 16 89992721 89992828 108 + 0.810 0.748 -0.249
ENSG00000223959 E039 5.3060245 0.1505147843 0.990375963 1.00000000 16 89993768 89993893 126 + 0.770 0.808 0.151
ENSG00000223959 E040 2.2207624 0.0068413893 0.808649819 0.92935967 16 89994693 89994758 66 + 0.478 0.518 0.192
ENSG00000223959 E041 22.2816566 0.0006308460 0.691920211 0.87388831 16 89994759 89995763 1005 + 1.369 1.352 -0.059
ENSG00000223959 E042 10.2622901 0.0014083700 0.288202058 0.58181950 16 89995764 89996043 280 + 0.983 1.081 0.361
ENSG00000223959 E043 26.4126904 0.0008680285 0.004260665 0.04437048 16 89996044 89996626 583 + 1.324 1.489 0.571
ENSG00000223959 E044 0.1265070 0.0123103470 0.751009995   16 89996783 89996892 110 + 0.000 0.082 12.166
ENSG00000223959 E045 0.0000000       16 89998606 89999195 590 +      
ENSG00000223959 E046 0.0000000       16 89999196 89999311 116 +      
ENSG00000223959 E047 0.0000000       16 89999312 89999823 512 +      
ENSG00000223959 E048 0.0000000       16 89999824 90000024 201 +      
ENSG00000223959 E049 0.0000000       16 90000103 90000297 195 +      
ENSG00000223959 E050 0.0000000       16 90000449 90002161 1713 +      

Help

Please Click HERE to learn more details about the results from DEXseq.