ENSG00000225138

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000534918 ENSG00000225138 No_inf pgKDN_inf   lncRNA retained_intron 25.55485 38.04883 14.19391 2.359637 0.7945555 -1.421943 1.3647702 1.5266712 0.5297437 1.0129022 0.5297437 -1.5094622 0.05240000 0.038550 0.033950 -0.004600 0.91304631 0.00771935 FALSE TRUE
ENST00000606319 ENSG00000225138 No_inf pgKDN_inf   lncRNA lncRNA 25.55485 38.04883 14.19391 2.359637 0.7945555 -1.421943 1.4545340 1.1307247 1.4236028 1.1307247 1.4236028 0.3296947 0.06541667 0.026150 0.091250 0.065100 0.90064259 0.00771935   FALSE
ENST00000607286 ENSG00000225138 No_inf pgKDN_inf   lncRNA lncRNA 25.55485 38.04883 14.19391 2.359637 0.7945555 -1.421943 2.7333896 5.4705504 1.0608554 1.0691417 0.4170782 -2.3555570 0.09495000 0.140850 0.075025 -0.065825 0.65237265 0.00771935 FALSE FALSE
ENST00000658086 ENSG00000225138 No_inf pgKDN_inf   lncRNA lncRNA 25.55485 38.04883 14.19391 2.359637 0.7945555 -1.421943 4.7258169 6.6343570 2.0816852 1.3302527 1.1716939 -1.6674638 0.17825000 0.170000 0.144225 -0.025775 0.83804119 0.00771935   FALSE
ENST00000658225 ENSG00000225138 No_inf pgKDN_inf   lncRNA lncRNA 25.55485 38.04883 14.19391 2.359637 0.7945555 -1.421943 0.6225549 0.0000000 1.5518411 0.0000000 0.5379369 7.2871038 0.04068333 0.000000 0.110250 0.110250 0.00771935 0.00771935 FALSE FALSE
MSTRG.22647.1 ENSG00000225138 No_inf pgKDN_inf   lncRNA   25.55485 38.04883 14.19391 2.359637 0.7945555 -1.421943 3.6388295 5.3992943 1.9992737 1.0684535 0.5661095 -1.4287663 0.14570833 0.148025 0.146650 -0.001375 1.00000000 0.00771935 TRUE FALSE
MSTRG.22647.10 ENSG00000225138 No_inf pgKDN_inf   lncRNA   25.55485 38.04883 14.19391 2.359637 0.7945555 -1.421943 3.2699393 4.5881120 2.4719385 0.8959010 0.8675356 -0.8895742 0.13511667 0.121950 0.169650 0.047700 0.87290526 0.00771935 FALSE TRUE
MSTRG.22647.6 ENSG00000225138 No_inf pgKDN_inf   lncRNA   25.55485 38.04883 14.19391 2.359637 0.7945555 -1.421943 0.5942746 0.6595593 1.1232645 0.6595593 0.6585455 0.7592010 0.03434167 0.016950 0.086075 0.069125 0.66410588 0.00771935 FALSE FALSE
MSTRG.22647.8 ENSG00000225138 No_inf pgKDN_inf   lncRNA   25.55485 38.04883 14.19391 2.359637 0.7945555 -1.421943 2.6642750 4.4032878 0.4480059 1.5851490 0.4480059 -3.2684157 0.09346667 0.120750 0.032125 -0.088625 0.50255050 0.00771935 FALSE TRUE
MSTRG.22647.9 ENSG00000225138 No_inf pgKDN_inf   lncRNA   25.55485 38.04883 14.19391 2.359637 0.7945555 -1.421943 3.2521530 7.0209647 0.6137228 0.4674555 0.3758838 -3.4947457 0.10659167 0.185000 0.046975 -0.138025 0.14499551 0.00771935   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000225138 E001 0.0000000       5 473153 473235 83 +      
ENSG00000225138 E002 0.2444846 0.0162938462 0.366812809   5 473236 473399 164 + 0.156 0.056 -1.651
ENSG00000225138 E003 6.1403126 0.0635887743 0.296361505 0.58944431 5 473748 474046 299 + 0.650 0.823 0.706
ENSG00000225138 E004 5.1226531 0.0032418440 0.749360411 0.90123769 5 475137 475283 147 + 0.691 0.734 0.179
ENSG00000225138 E005 2.8565096 0.0054894836 0.488507593 0.75177273 5 475284 475319 36 + 0.606 0.506 -0.459
ENSG00000225138 E006 1.4896052 0.2457537432 0.463805507 0.73353135 5 476050 476231 182 + 0.437 0.323 -0.650
ENSG00000225138 E007 0.7519000 0.0133690366 0.696099704 0.87604054 5 476232 476407 176 + 0.156 0.228 0.671
ENSG00000225138 E008 4.8624672 0.0270340462 0.904958882 0.96954500 5 476408 476492 85 + 0.691 0.711 0.086
ENSG00000225138 E009 3.7397939 0.0298836159 0.948535459 0.98667884 5 476493 476534 42 + 0.606 0.621 0.065
ENSG00000225138 E010 0.9879478 0.0118326806 0.400949093 0.68417719 5 476535 476563 29 + 0.362 0.228 -0.914
ENSG00000225138 E011 0.0000000       5 476670 476671 2 +      
ENSG00000225138 E012 0.0000000       5 476672 476676 5 +      
ENSG00000225138 E013 14.0876301 0.0011363438 0.004322056 0.04476777 5 476677 476973 297 + 0.875 1.158 1.042
ENSG00000225138 E014 8.7223358 0.0016510995 0.746151410 0.89960500 5 476974 477053 80 + 0.945 0.913 -0.121
ENSG00000225138 E015 7.1078334 0.0020387026 0.929107667 0.97904564 5 477054 477103 50 + 0.850 0.841 -0.032
ENSG00000225138 E016 11.3511271 0.0052961594 0.978691871 0.99716194 5 477104 477243 140 + 1.023 1.022 -0.002
ENSG00000225138 E017 4.1239971 0.0248865339 0.724455109 0.88936406 5 477244 477244 1 + 0.606 0.662 0.242
ENSG00000225138 E018 5.3846005 0.0243084940 0.436271716 0.71272426 5 477245 477321 77 + 0.650 0.766 0.478
ENSG00000225138 E019 1.0147640 0.0114921161 0.089013501 0.30959181 5 477322 477336 15 + 0.001 0.323 9.853
ENSG00000225138 E020 0.8697853 0.1698945052 0.812823590 0.93125497 5 477337 477465 129 + 0.271 0.228 -0.328
ENSG00000225138 E021 7.0809845 0.0023159263 0.196407076 0.47705558 5 477585 477805 221 + 0.945 0.805 -0.536
ENSG00000225138 E022 6.3379330 0.0023716745 0.380972802 0.66740425 5 477806 477849 44 + 0.875 0.776 -0.388
ENSG00000225138 E023 8.8374952 0.0017157325 0.595365625 0.82207184 5 477850 477975 126 + 0.966 0.913 -0.199
ENSG00000225138 E024 8.7259891 0.0016372737 0.745710188 0.89945507 5 477976 478122 147 + 0.945 0.913 -0.121
ENSG00000225138 E025 59.4938514 0.0002865422 0.693768390 0.87489497 5 478123 479507 1385 + 1.718 1.704 -0.046
ENSG00000225138 E026 5.3641414 0.0547532154 0.802947271 0.92677106 5 479508 479781 274 + 0.761 0.734 -0.111
ENSG00000225138 E027 0.0000000       5 479782 479865 84 +      
ENSG00000225138 E028 2.7495442 0.0051773897 0.884372638 0.96108634 5 479866 479997 132 + 0.501 0.525 0.114
ENSG00000225138 E029 9.9600341 0.0014533574 0.473491236 0.74051141 5 479998 480067 70 + 1.023 0.955 -0.253
ENSG00000225138 E030 19.8498104 0.0007411802 0.812575990 0.93110974 5 480068 480216 149 + 1.232 1.252 0.070
ENSG00000225138 E031 10.8211652 0.0105856068 0.329976318 0.62255336 5 480217 480361 145 + 1.074 0.981 -0.341
ENSG00000225138 E032 48.0616475 0.0006333999 0.737299292 0.89586003 5 480362 480884 523 + 1.603 1.621 0.061

Help

Please Click HERE to learn more details about the results from DEXseq.