ENSG00000225339

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000429998 ENSG00000225339 No_inf pgKDN_inf   lncRNA retained_intron 10.02999 7.23787 11.3577 0.9459914 1.217067 0.649312 0.8567115 2.5701346 0.0000000 0.8575558 0.0000000 -8.0113025 0.11097500 0.332925 0.000000 -0.332925 0.009962103 0.009962103 FALSE FALSE
ENST00000586726 ENSG00000225339 No_inf pgKDN_inf   lncRNA lncRNA 10.02999 7.23787 11.3577 0.9459914 1.217067 0.649312 0.6611020 1.0247432 0.5612036 1.0247432 0.3881681 -0.8571957 0.06806667 0.116400 0.053775 -0.062625 0.913079729 0.009962103 TRUE FALSE
ENST00000593917 ENSG00000225339 No_inf pgKDN_inf   lncRNA lncRNA 10.02999 7.23787 11.3577 0.9459914 1.217067 0.649312 4.2093195 1.0577386 5.4019230 0.7753201 0.7217061 2.3415828 0.40079167 0.199850 0.476000 0.276150 0.328786462 0.009962103   FALSE
ENST00000659015 ENSG00000225339 No_inf pgKDN_inf   lncRNA lncRNA 10.02999 7.23787 11.3577 0.9459914 1.217067 0.649312 0.8578829 1.5048006 0.7885560 0.5289154 0.3052503 -0.9236624 0.10860833 0.228475 0.068200 -0.160275 0.689832443 0.009962103 FALSE FALSE
MSTRG.24572.3 ENSG00000225339 No_inf pgKDN_inf   lncRNA   10.02999 7.23787 11.3577 0.9459914 1.217067 0.649312 3.1148236 0.7822262 4.6060215 0.4629343 0.7814631 2.5426657 0.27557500 0.088600 0.402025 0.313425 0.106633245 0.009962103   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000225339 E001 0.4816726 0.019740036 0.478258968   6 34248535 34248550 16 + 0.219 0.105 -1.259
ENSG00000225339 E002 0.2357071 0.016875697 0.357242683   6 34248551 34248580 30 + 0.158 0.000 -10.283
ENSG00000225339 E003 1.9055876 0.009825444 0.005900359 0.05582982 6 34248581 34248670 90 + 0.609 0.190 -2.482
ENSG00000225339 E004 1.7826177 0.018635961 0.012224450 0.09154588 6 34260379 34260561 183 + 0.585 0.190 -2.374
ENSG00000225339 E005 0.2362687 0.017442822 0.356173838   6 34263276 34263279 4 + 0.158 0.000 -10.283
ENSG00000225339 E006 0.8464295 0.017027989 0.431498529 0.70922294 6 34263280 34263799 520 + 0.321 0.190 -0.996
ENSG00000225339 E007 0.8720163 0.014513848 0.118941336 0.36449126 6 34272465 34272488 24 + 0.158 0.375 1.648
ENSG00000225339 E008 2.6013531 0.006096167 0.016539198 0.11198492 6 34277908 34278182 275 + 0.403 0.685 1.326
ENSG00000225339 E009 0.3629044 0.017783748 0.783988262   6 34278579 34278661 83 + 0.158 0.105 -0.674
ENSG00000225339 E010 6.3816750 0.002715817 0.035930686 0.18184157 6 34279140 34279703 564 + 0.796 0.938 0.548
ENSG00000225339 E011 0.0000000       6 34279704 34281321 1618 +      
ENSG00000225339 E012 0.0000000       6 34281322 34281914 593 +      
ENSG00000225339 E013 0.0000000       6 34281915 34282562 648 +      
ENSG00000225339 E014 0.0000000       6 34282563 34283872 1310 +      
ENSG00000225339 E015 0.0000000       6 34283873 34286768 2896 +      

Help

Please Click HERE to learn more details about the results from DEXseq.