ENSG00000234741

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000412059 ENSG00000234741 No_inf pgKDN_inf GAS5 lncRNA retained_intron 262.2249 339.6922 247.6477 6.82348 6.805207 -0.4559235 14.706995 14.89790 13.75384 1.932246 5.448073 -0.11519455 0.05849167 0.043725 0.055200 0.011475 9.843840e-01 6.779137e-20 FALSE FALSE
ENST00000687189 ENSG00000234741 No_inf pgKDN_inf GAS5 lncRNA lncRNA 262.2249 339.6922 247.6477 6.82348 6.805207 -0.4559235 19.040365 22.71101 22.44782 3.992857 8.208538 -0.01680926 0.07147500 0.066500 0.088725 0.022225 1.000000e+00 6.779137e-20   FALSE
ENST00000689238 ENSG00000234741 No_inf pgKDN_inf GAS5 lncRNA lncRNA 262.2249 339.6922 247.6477 6.82348 6.805207 -0.4559235 137.509885 202.44523 115.33128 4.840855 5.134345 -0.81169394 0.51366667 0.597125 0.466300 -0.130825 2.128121e-02 6.779137e-20   FALSE
ENST00000689958 ENSG00000234741 No_inf pgKDN_inf GAS5 lncRNA lncRNA 262.2249 339.6922 247.6477 6.82348 6.805207 -0.4559235 6.034633 18.10390 0.00000 1.558428 0.000000 -10.82288133 0.01780000 0.053400 0.000000 -0.053400 6.779137e-20 6.779137e-20   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000234741 E001 5.671003 0.0024586072 9.511184e-01 9.876323e-01 1 173858559 173858996 438 - 0.813 0.818 0.021
ENSG00000234741 E002 5.893753 0.0242037152 6.185296e-01 8.349577e-01 1 173858997 173859305 309 - 0.868 0.805 -0.245
ENSG00000234741 E003 0.000000       1 173863810 173863894 85 -      
ENSG00000234741 E004 0.000000       1 173863895 173863898 4 -      
ENSG00000234741 E005 0.000000       1 173863899 173863899 1 -      
ENSG00000234741 E006 0.000000       1 173863900 173863900 1 -      
ENSG00000234741 E007 0.000000       1 173863901 173863901 1 -      
ENSG00000234741 E008 0.000000       1 173863902 173863910 9 -      
ENSG00000234741 E009 0.000000       1 173863911 173863930 20 -      
ENSG00000234741 E010 20.019014 0.0088597606 3.422702e-01 6.336933e-01 1 173863931 173863979 49 - 1.356 1.283 -0.255
ENSG00000234741 E011 65.632996 0.0025364222 4.222699e-01 7.015783e-01 1 173863980 173864033 54 - 1.795 1.827 0.108
ENSG00000234741 E012 88.215407 0.0001859335 4.513564e-02 2.077796e-01 1 173864034 173864075 42 - 1.902 1.966 0.214
ENSG00000234741 E013 4.410621 0.0031138100 3.250729e-01 6.175802e-01 1 173864076 173864098 23 - 0.793 0.674 -0.486
ENSG00000234741 E014 4.157298 0.0035390812 1.960915e-01 4.766970e-01 1 173864099 173864143 45 - 0.793 0.634 -0.656
ENSG00000234741 E015 11.666082 0.0040491952 3.904695e-01 6.760483e-01 1 173864144 173864256 113 - 1.138 1.062 -0.273
ENSG00000234741 E016 121.680060 0.0001387707 1.543228e-01 4.196886e-01 1 173864257 173864304 48 - 2.057 2.094 0.126
ENSG00000234741 E017 43.216776 0.0069002740 1.636348e-06 7.151930e-05 1 173864305 173864483 179 - 1.781 1.505 -0.937
ENSG00000234741 E018 100.052687 0.0001570144 2.916660e-01 5.851242e-01 1 173864484 173864502 19 - 1.977 2.007 0.102
ENSG00000234741 E019 86.826101 0.0001885717 4.431702e-01 7.182382e-01 1 173864503 173864506 4 - 1.920 1.944 0.078
ENSG00000234741 E020 43.477309 0.0003527077 1.542192e-03 2.089339e-02 1 173864507 173864674 168 - 1.721 1.575 -0.494
ENSG00000234741 E021 116.376296 0.0001355211 1.749818e-02 1.159964e-01 1 173864675 173864704 30 - 2.020 2.086 0.220
ENSG00000234741 E022 50.863361 0.0003242031 1.054027e-11 1.194283e-09 1 173864705 173865228 524 - 1.855 1.568 -0.974
ENSG00000234741 E023 111.336238 0.0001613316 1.797929e-01 4.550346e-01 1 173865229 173865243 15 - 2.019 2.056 0.124
ENSG00000234741 E024 90.386653 0.0031095590 5.211826e-02 2.267011e-01 1 173865244 173865248 5 - 1.905 1.980 0.252
ENSG00000234741 E025 125.385605 0.0039613481 1.390806e-01 3.965728e-01 1 173865249 173865282 34 - 2.060 2.113 0.176
ENSG00000234741 E026 15.868796 0.0139640200 1.044561e-02 8.265455e-02 1 173865283 173865352 70 - 1.340 1.114 -0.798
ENSG00000234741 E027 20.555315 0.0006577690 6.481000e-06 2.339667e-04 1 173865353 173865470 118 - 1.477 1.184 -1.021
ENSG00000234741 E028 55.232481 0.0003189079 8.440403e-01 9.441949e-01 1 173865471 173865509 39 - 1.737 1.743 0.021
ENSG00000234741 E029 127.436273 0.0001366937 5.460781e-02 2.327963e-01 1 173865510 173865547 38 - 2.069 2.119 0.168
ENSG00000234741 E030 2.630511 0.0413721792 4.625157e-04 8.224636e-03 1 173865548 173865565 18 - 0.793 0.262 -2.656
ENSG00000234741 E031 7.314023 0.0018940628 5.822926e-09 4.308007e-07 1 173865566 173865817 252 - 1.173 0.567 -2.371
ENSG00000234741 E032 2.896279 0.0115602357 5.302557e-03 5.173715e-02 1 173865818 173865856 39 - 0.773 0.389 -1.766
ENSG00000234741 E033 134.290747 0.0002019634 1.025820e-01 3.348484e-01 1 173865857 173865894 38 - 2.097 2.138 0.139
ENSG00000234741 E034 6.834408 0.0405478905 1.792663e-01 4.543492e-01 1 173865895 173865952 58 - 0.986 0.805 -0.692
ENSG00000234741 E035 10.084926 0.0014136415 8.280081e-04 1.295180e-02 1 173865953 173866176 224 - 1.190 0.893 -1.086
ENSG00000234741 E036 107.848338 0.0001589342 7.641962e-01 9.081970e-01 1 173866177 173866199 23 - 2.024 2.031 0.024
ENSG00000234741 E037 84.375704 0.0001863532 3.653674e-01 6.539149e-01 1 173866200 173866206 7 - 1.905 1.933 0.095
ENSG00000234741 E038 8.714863 0.0016407086 7.236954e-05 1.806191e-03 1 173866207 173866527 321 - 1.165 0.790 -1.397
ENSG00000234741 E039 123.720576 0.0001479485 2.759734e-01 5.693436e-01 1 173866528 173866567 40 - 2.070 2.098 0.094
ENSG00000234741 E040 7.551628 0.0017605372 1.603089e-09 1.320015e-07 1 173866568 173866581 14 - 1.190 0.567 -2.430
ENSG00000234741 E041 12.928378 0.0209069922 4.105250e-06 1.586050e-04 1 173866582 173866760 179 - 1.351 0.893 -1.652
ENSG00000234741 E042 159.097588 0.0001062342 7.050658e-02 2.688372e-01 1 173866761 173866796 36 - 2.170 2.211 0.139
ENSG00000234741 E043 1.568141 0.0513281562 6.526889e-02 2.571982e-01 1 173866797 173866990 194 - 0.557 0.262 -1.656
ENSG00000234741 E044 122.349942 0.0001375780 5.907030e-02 2.438685e-01 1 173866991 173867043 53 - 2.051 2.102 0.168
ENSG00000234741 E045 1.714296 0.0464350294 5.662927e-01 8.046452e-01 1 173867044 173867154 111 - 0.481 0.389 -0.486
ENSG00000234741 E046 5.522683 0.0025118407 5.115660e-01 7.687460e-01 1 173867155 173867721 567 - 0.850 0.776 -0.294
ENSG00000234741 E047 1.578947 0.0105367954 1.587689e-01 4.258339e-01 1 173867722 173867959 238 - 0.521 0.308 -1.164
ENSG00000234741 E048 46.194438 0.0032321039 2.109419e-01 4.957704e-01 1 173867960 173867980 21 - 1.628 1.688 0.206
ENSG00000234741 E049 4.671197 0.0034265332 7.161086e-01 8.855146e-01 1 173867981 173868009 29 - 0.773 0.728 -0.181
ENSG00000234741 E050 0.000000       1 173868754 173868882 129 -      

Help

Please Click HERE to learn more details about the results from DEXseq.