ENSG00000237441

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000437840 ENSG00000237441 No_inf pgKDN_inf RGL2 protein_coding protein_coding_CDS_not_defined 49.51631 89.70394 30.64981 1.734212 1.72301 -1.548983 6.8765401 8.7262089 8.575458 2.2101376 1.3978965 -0.02511227 0.16631667 0.096350 0.287050 0.190700 8.469696e-02 7.477874e-18 FALSE TRUE
ENST00000483151 ENSG00000237441 No_inf pgKDN_inf RGL2 protein_coding retained_intron 49.51631 89.70394 30.64981 1.734212 1.72301 -1.548983 2.6783830 0.7443193 3.146890 0.7443193 1.7425922 2.06525687 0.08290833 0.008425 0.095000 0.086575 2.463181e-01 7.477874e-18 TRUE TRUE
ENST00000491168 ENSG00000237441 No_inf pgKDN_inf RGL2 protein_coding protein_coding_CDS_not_defined 49.51631 89.70394 30.64981 1.734212 1.72301 -1.548983 0.8177415 0.0000000 1.916118 0.0000000 1.9161176 7.58955195 0.02445833 0.000000 0.054475 0.054475 7.152674e-01 7.477874e-18 FALSE TRUE
MSTRG.24540.1 ENSG00000237441 No_inf pgKDN_inf RGL2 protein_coding   49.51631 89.70394 30.64981 1.734212 1.72301 -1.548983 11.1865464 31.3652855 0.000000 4.8689536 0.0000000 -11.61541287 0.14554167 0.352275 0.000000 -0.352275 7.477874e-18 7.477874e-18 FALSE TRUE
MSTRG.24540.14 ENSG00000237441 No_inf pgKDN_inf RGL2 protein_coding   49.51631 89.70394 30.64981 1.734212 1.72301 -1.548983 2.9215584 5.0971143 2.243045 1.4096933 0.8552869 -1.18063247 0.06160833 0.057675 0.075575 0.017900 9.979958e-01 7.477874e-18 FALSE TRUE
MSTRG.24540.2 ENSG00000237441 No_inf pgKDN_inf RGL2 protein_coding   49.51631 89.70394 30.64981 1.734212 1.72301 -1.548983 4.4848593 8.8464889 3.772468 3.6887898 0.7682167 -1.22740686 0.08540000 0.099325 0.127125 0.027800 8.430432e-01 7.477874e-18 FALSE TRUE
MSTRG.24540.4 ENSG00000237441 No_inf pgKDN_inf RGL2 protein_coding   49.51631 89.70394 30.64981 1.734212 1.72301 -1.548983 5.4848659 10.7977829 1.655688 0.4651429 0.7481914 -2.69788070 0.10630833 0.120375 0.056975 -0.063400 4.426454e-01 7.477874e-18 FALSE TRUE
MSTRG.24540.5 ENSG00000237441 No_inf pgKDN_inf RGL2 protein_coding   49.51631 89.70394 30.64981 1.734212 1.72301 -1.548983 3.5087267 6.5845608 1.509530 1.4258926 0.8885596 -2.11765146 0.06972500 0.073350 0.045225 -0.028125 7.331428e-01 7.477874e-18 FALSE TRUE
MSTRG.24540.7 ENSG00000237441 No_inf pgKDN_inf RGL2 protein_coding   49.51631 89.70394 30.64981 1.734212 1.72301 -1.548983 3.9526202 4.5019579 3.564995 4.5019579 2.0852629 -0.33581241 0.10075833 0.047725 0.124550 0.076825 8.014790e-01 7.477874e-18 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000237441 E001 0.6240057 0.1729612321 1.000000e+00 1.000000e+00 6 33291654 33291660 7 - 0.166 0.181 0.160
ENSG00000237441 E002 4.4090577 0.0035314071 1.082864e-01 3.451725e-01 6 33291661 33291677 17 - 0.455 0.701 1.121
ENSG00000237441 E003 156.8999687 0.0001237737 1.647874e-01 4.342213e-01 6 33291678 33292105 428 - 2.077 2.115 0.129
ENSG00000237441 E004 99.2313122 0.0001872655 2.026877e-01 4.851963e-01 6 33292106 33292313 208 - 1.946 1.901 -0.153
ENSG00000237441 E005 4.5165516 0.0352444539 4.783049e-01 7.443272e-01 6 33292314 33292429 116 - 0.577 0.689 0.488
ENSG00000237441 E006 54.1698125 0.0003365468 4.303987e-01 7.083186e-01 6 33292430 33292544 115 - 1.682 1.644 -0.131
ENSG00000237441 E007 35.4816571 0.0045865266 8.311586e-02 2.971083e-01 6 33293016 33293094 79 - 1.558 1.449 -0.374
ENSG00000237441 E008 66.9178669 0.0015545467 5.254768e-01 7.782127e-01 6 33293095 33293306 212 - 1.766 1.736 -0.101
ENSG00000237441 E009 52.7800052 0.0050904217 5.687619e-01 8.060140e-01 6 33293413 33293524 112 - 1.615 1.648 0.111
ENSG00000237441 E010 9.2612938 0.0042893618 7.285232e-01 8.917609e-01 6 33293525 33293603 79 - 0.899 0.937 0.142
ENSG00000237441 E011 45.5061768 0.0003252509 8.098367e-01 9.298226e-01 6 33293604 33293699 96 - 1.569 1.581 0.041
ENSG00000237441 E012 5.7661136 0.0024610869 4.460722e-01 7.204642e-01 6 33293700 33293794 95 - 0.672 0.773 0.414
ENSG00000237441 E013 53.5940917 0.0012525089 7.482563e-01 9.006397e-01 6 33293795 33293906 112 - 1.661 1.644 -0.059
ENSG00000237441 E014 21.6834717 0.0049053213 2.467054e-01 5.373059e-01 6 33293907 33293913 7 - 1.338 1.249 -0.314
ENSG00000237441 E015 18.0672896 0.0118711644 2.756612e-01 5.692575e-01 6 33293914 33293916 3 - 1.269 1.172 -0.340
ENSG00000237441 E016 5.7538455 0.0793806052 9.219941e-01 9.757812e-01 6 33293917 33293935 19 - 0.750 0.753 0.014
ENSG00000237441 E017 5.5046988 0.0157204479 8.253539e-01 9.367500e-01 6 33293936 33294033 98 - 0.713 0.743 0.126
ENSG00000237441 E018 31.3520151 0.0038357643 7.818416e-01 9.160998e-01 6 33294034 33294066 33 - 1.437 1.418 -0.067
ENSG00000237441 E019 1.5037675 0.0372190984 6.638998e-01 8.601986e-01 6 33294067 33294242 176 - 0.284 0.361 0.488
ENSG00000237441 E020 36.7918851 0.0021283741 2.703287e-01 5.639858e-01 6 33294688 33294762 75 - 1.541 1.474 -0.229
ENSG00000237441 E021 18.3109131 0.0013835528 1.929293e-01 4.727265e-01 6 33294977 33294995 19 - 1.279 1.176 -0.364
ENSG00000237441 E022 30.2614350 0.0004403826 7.425023e-01 8.982576e-01 6 33294996 33295045 50 - 1.390 1.411 0.071
ENSG00000237441 E023 39.3608106 0.0004412086 9.020871e-01 9.686671e-01 6 33295127 33295211 85 - 1.523 1.515 -0.026
ENSG00000237441 E024 41.0885983 0.0036750862 4.518499e-02 2.077939e-01 6 33295319 33295422 104 - 1.625 1.508 -0.396
ENSG00000237441 E025 65.1413267 0.0002542048 3.129582e-01 6.063377e-01 6 33295508 33295686 179 - 1.766 1.721 -0.151
ENSG00000237441 E026 44.2383451 0.0003283853 9.304035e-01 9.796588e-01 6 33295687 33295759 73 - 1.563 1.567 0.013
ENSG00000237441 E027 30.3108246 0.0014536829 3.639757e-04 6.805055e-03 6 33295760 33295805 46 - 1.185 1.451 0.926
ENSG00000237441 E028 70.1499275 0.0007722961 1.091178e-06 5.021466e-05 6 33295806 33296027 222 - 1.563 1.802 0.809
ENSG00000237441 E029 18.4458850 0.0008143122 2.827845e-01 5.764277e-01 6 33296028 33296045 18 - 1.269 1.184 -0.300
ENSG00000237441 E030 17.5234784 0.0008510786 3.066435e-02 1.647397e-01 6 33296046 33296098 53 - 1.310 1.141 -0.597
ENSG00000237441 E031 19.9719990 0.0064586460 7.411218e-01 8.972920e-01 6 33296099 33296156 58 - 1.258 1.229 -0.101
ENSG00000237441 E032 22.0529780 0.0006176801 2.176784e-01 5.041944e-01 6 33296157 33296217 61 - 1.198 1.294 0.336
ENSG00000237441 E033 29.4386293 0.0004786722 2.231110e-01 5.105983e-01 6 33296218 33296325 108 - 1.329 1.411 0.284
ENSG00000237441 E034 24.7508465 0.0011558199 9.368383e-01 9.819924e-01 6 33296414 33296443 30 - 1.320 1.324 0.016
ENSG00000237441 E035 23.5873534 0.0012648975 5.447018e-01 7.910820e-01 6 33296444 33296464 21 - 1.338 1.294 -0.156
ENSG00000237441 E036 41.5463770 0.0031249288 3.345191e-01 6.263262e-01 6 33296598 33296776 179 - 1.585 1.527 -0.196
ENSG00000237441 E037 0.0000000       6 33297032 33297115 84 -      
ENSG00000237441 E038 0.0000000       6 33297116 33297213 98 -      
ENSG00000237441 E039 0.0000000       6 33297214 33297343 130 -      
ENSG00000237441 E040 0.0000000       6 33297344 33297692 349 -      
ENSG00000237441 E041 0.0000000       6 33297931 33297993 63 -      
ENSG00000237441 E042 11.5729711 0.0012835091 2.947407e-02 1.613371e-01 6 33298455 33298651 197 - 0.816 1.056 0.903
ENSG00000237441 E043 0.3714000 0.0165714670 5.961498e-01   6 33298652 33298810 159 - 0.165 0.100 -0.834
ENSG00000237441 E044 4.7602225 0.0031858485 5.958730e-01 8.223176e-01 6 33298870 33298951 82 - 0.627 0.701 0.313

Help

Please Click HERE to learn more details about the results from DEXseq.