ENSG00000254087

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000420292 ENSG00000254087 No_inf pgKDN_inf LYN protein_coding protein_coding_CDS_not_defined 89.06521 29.93485 119.6642 2.311271 4.617926 1.998732 16.496943 1.283094 22.91330 1.283094 2.0873645 4.147915 0.14541667 0.042350 0.190950 0.14860 0.03024438 0.03024438 FALSE FALSE
ENST00000519728 ENSG00000254087 No_inf pgKDN_inf LYN protein_coding protein_coding 89.06521 29.93485 119.6642 2.311271 4.617926 1.998732 42.745049 15.971050 57.38437 3.741583 0.9394786 1.844547 0.50239167 0.554425 0.480975 -0.07345 0.84565872 0.03024438 FALSE TRUE
ENST00000520050 ENSG00000254087 No_inf pgKDN_inf LYN protein_coding protein_coding 89.06521 29.93485 119.6642 2.311271 4.617926 1.998732 9.209956 2.723357 16.80103 2.723357 3.5413637 2.620662 0.09134167 0.074950 0.138400 0.06345 0.13558460 0.03024438 FALSE FALSE
ENST00000520220 ENSG00000254087 No_inf pgKDN_inf LYN protein_coding protein_coding 89.06521 29.93485 119.6642 2.311271 4.617926 1.998732 20.613259 9.957348 22.56549 3.808343 0.4050753 1.179476 0.26085000 0.328275 0.189675 -0.13860 0.85620683 0.03024438 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000254087 E001 50.6719612 6.636228e-04 1.807020e-01 4.564008e-01 8 55879835 55880103 269 + 1.681 1.615 -0.225
ENSG00000254087 E002 0.0000000       8 55940234 55940327 94 +      
ENSG00000254087 E003 47.0386885 3.344549e-04 1.194949e-01 3.653950e-01 8 55941855 55941928 74 + 1.653 1.574 -0.269
ENSG00000254087 E004 33.8781533 4.043108e-04 1.130701e-02 8.720568e-02 8 55941929 55941991 63 + 1.531 1.377 -0.532
ENSG00000254087 E005 39.4114743 2.780231e-02 7.872911e-01 9.183776e-01 8 55946448 55946493 46 + 1.563 1.544 -0.065
ENSG00000254087 E006 62.1214422 2.569987e-04 3.299877e-01 6.225534e-01 8 55947618 55947723 106 + 1.762 1.719 -0.144
ENSG00000254087 E007 66.9407004 2.514025e-04 3.825877e-01 6.688415e-01 8 55950459 55950557 99 + 1.792 1.756 -0.124
ENSG00000254087 E008 59.7261200 5.007187e-03 7.366280e-01 8.955502e-01 8 55950681 55950784 104 + 1.729 1.746 0.056
ENSG00000254087 E009 85.0734766 3.735633e-03 4.818242e-01 7.467874e-01 8 55951966 55952115 150 + 1.894 1.862 -0.109
ENSG00000254087 E010 97.2208325 2.167359e-04 6.759780e-02 2.623276e-01 8 55953832 55953984 153 + 1.959 1.895 -0.216
ENSG00000254087 E011 0.2356421 1.569892e-02 1.000000e+00   8 55955096 55955293 198 + 0.110 0.001 -7.783
ENSG00000254087 E012 117.5123526 1.305833e-04 2.709355e-01 5.646304e-01 8 55966715 55966897 183 + 2.033 1.998 -0.117
ENSG00000254087 E013 69.1074129 2.791097e-04 8.459098e-02 3.005092e-01 8 55969717 55969793 77 + 1.815 1.743 -0.244
ENSG00000254087 E014 118.5967144 1.626719e-03 1.083695e-01 3.453353e-01 8 55998346 55998499 154 + 2.043 1.986 -0.192
ENSG00000254087 E015 121.1045898 1.558275e-04 9.316155e-01 9.800034e-01 8 55999418 55999549 132 + 2.038 2.035 -0.010
ENSG00000254087 E016 934.2512111 4.446602e-05 6.286401e-08 3.831082e-06 8 56009908 56014169 4262 + 2.909 2.951 0.142

Help

Please Click HERE to learn more details about the results from DEXseq.