ENSG00000256525

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000539111 ENSG00000256525 No_inf pgKDN_inf POLG2 protein_coding protein_coding 10.44823 11.70976 9.193651 0.8282429 1.270568 -0.3486644 2.6373840 1.9280760 3.1714471 0.7316276 0.3180277 0.7150580 0.26660833 0.159200 0.358975 0.199775 0.48407669 0.02761047 FALSE TRUE
ENST00000580893 ENSG00000256525 No_inf pgKDN_inf POLG2 protein_coding protein_coding_CDS_not_defined 10.44823 11.70976 9.193651 0.8282429 1.270568 -0.3486644 1.7396935 1.6986675 1.3560257 0.7747330 0.8230873 -0.3228871 0.15272500 0.135700 0.134375 -0.001325 0.94824132 0.02761047 FALSE FALSE
ENST00000582501 ENSG00000256525 No_inf pgKDN_inf POLG2 protein_coding protein_coding_CDS_not_defined 10.44823 11.70976 9.193651 0.8282429 1.270568 -0.3486644 2.7705783 3.9193444 2.2741073 0.4364452 0.2207695 -0.7826582 0.26996667 0.334725 0.267450 -0.067275 0.83828826 0.02761047 FALSE FALSE
ENST00000673460 ENSG00000256525 No_inf pgKDN_inf POLG2 protein_coding nonsense_mediated_decay 10.44823 11.70976 9.193651 0.8282429 1.270568 -0.3486644 0.7693579 0.8207125 0.4645006 0.4126220 0.1587677 -0.8079394 0.07761667 0.069750 0.056425 -0.013325 1.00000000 0.02761047 TRUE TRUE
MSTRG.13128.4 ENSG00000256525 No_inf pgKDN_inf POLG2 protein_coding   10.44823 11.70976 9.193651 0.8282429 1.270568 -0.3486644 0.9316477 2.0183629 0.0957258 0.4806090 0.0957258 -4.2619165 0.08460000 0.182150 0.008800 -0.173350 0.02761047 0.02761047 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000256525 E001 0.1271363 0.012558785 1.000000000   17 64477785 64477786 2 - 0.000 0.072 8.780
ENSG00000256525 E002 0.3712766 0.216643923 1.000000000   17 64477787 64477811 25 - 0.125 0.133 0.101
ENSG00000256525 E003 0.7521823 0.054869260 0.359638015 0.64911833 17 64477812 64477835 24 - 0.125 0.278 1.422
ENSG00000256525 E004 1.0058902 0.012051291 0.165691547 0.43551868 17 64477836 64477839 4 - 0.125 0.353 1.907
ENSG00000256525 E005 1.4880594 0.009469366 0.948173650 0.98654009 17 64477840 64477851 12 - 0.369 0.386 0.100
ENSG00000256525 E006 4.4166318 0.034381595 0.140349641 0.39866821 17 64477852 64477963 112 - 0.825 0.644 -0.739
ENSG00000256525 E007 2.3227799 0.037577957 0.119664961 0.36562486 17 64477964 64477988 25 - 0.638 0.417 -1.052
ENSG00000256525 E008 3.4501808 0.004711641 0.345626044 0.63651933 17 64480289 64480347 59 - 0.700 0.587 -0.485
ENSG00000256525 E009 5.0393625 0.052064718 0.271344872 0.56506870 17 64480348 64480389 42 - 0.846 0.709 -0.546
ENSG00000256525 E010 1.3604239 0.009407939 0.886395116 0.96201122 17 64481246 64481446 201 - 0.369 0.353 -0.093
ENSG00000256525 E011 6.4163694 0.023144790 0.566116179 0.80455556 17 64482919 64482974 56 - 0.886 0.828 -0.222
ENSG00000256525 E012 4.0969719 0.007536413 0.630718873 0.84150979 17 64482975 64482999 25 - 0.638 0.709 0.302
ENSG00000256525 E013 2.4672281 0.005920430 0.592836348 0.82050315 17 64483390 64483506 117 - 0.565 0.498 -0.315
ENSG00000256525 E014 15.6569137 0.047743028 0.003521355 0.03889896 17 64483964 64485157 1194 - 0.939 1.285 1.249
ENSG00000256525 E015 7.3830151 0.002170613 0.016885850 0.11335840 17 64485158 64485727 570 - 0.700 0.974 1.070
ENSG00000256525 E016 8.4098149 0.002182280 0.659707934 0.85798308 17 64485728 64485868 141 - 0.971 0.940 -0.118
ENSG00000256525 E017 3.3550735 0.017561582 0.623905155 0.83816961 17 64486898 64486988 91 - 0.565 0.644 0.348
ENSG00000256525 E018 2.5003693 0.007288765 0.161345678 0.42940300 17 64486989 64487068 80 - 0.369 0.587 1.100
ENSG00000256525 E019 9.9138017 0.003181681 0.924473260 0.97715075 17 64487069 64487745 677 - 1.001 1.021 0.073
ENSG00000256525 E020 3.2175523 0.005390436 0.967026794 0.99337266 17 64488843 64488937 95 - 0.603 0.607 0.018
ENSG00000256525 E021 3.1795681 0.122504868 0.236368714 0.52543134 17 64490469 64490677 209 - 0.728 0.522 -0.898
ENSG00000256525 E022 4.1860628 0.018112031 0.272295849 0.56606790 17 64490796 64490861 66 - 0.779 0.644 -0.559
ENSG00000256525 E023 4.3026345 0.069259067 0.322778591 0.61567197 17 64490862 64490969 108 - 0.803 0.644 -0.653
ENSG00000256525 E024 4.4655693 0.003377155 0.905181979 0.96961440 17 64492667 64492772 106 - 0.700 0.724 0.100
ENSG00000256525 E025 0.7621583 0.013588233 0.060993845 0.24792706 17 64492773 64492894 122 - 0.000 0.317 11.914
ENSG00000256525 E026 2.4883533 0.007245675 0.682383513 0.86858482 17 64492895 64492916 22 - 0.478 0.545 0.322
ENSG00000256525 E027 4.8284794 0.004118707 0.835430033 0.94082693 17 64492917 64493021 105 - 0.754 0.739 -0.063
ENSG00000256525 E028 3.2184418 0.039809352 0.979743962 0.99764964 17 64496407 64496531 125 - 0.603 0.607 0.017
ENSG00000256525 E029 12.4327508 0.001252860 0.071310378 0.27055491 17 64496532 64497128 597 - 1.187 1.057 -0.468

Help

Please Click HERE to learn more details about the results from DEXseq.