ENSG00000257103

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000433627 ENSG00000257103 No_inf pgKDN_inf LSM14A protein_coding protein_coding 51.11093 54.55342 53.88448 8.516641 9.14257 -0.01779656 4.082597 0.000000 9.5862253 0.000000 2.1780353 9.90632322 0.08983333 0.000000 0.203900 0.203900 1.786283e-08 1.786283e-08 FALSE TRUE
ENST00000544216 ENSG00000257103 No_inf pgKDN_inf LSM14A protein_coding protein_coding 51.11093 54.55342 53.88448 8.516641 9.14257 -0.01779656 22.241622 23.777104 19.6889182 1.514592 0.8164632 -0.27206324 0.47025000 0.469025 0.399875 -0.069150 8.423181e-01 1.786283e-08 FALSE TRUE
ENST00000585887 ENSG00000257103 No_inf pgKDN_inf LSM14A protein_coding non_stop_decay 51.11093 54.55342 53.88448 8.516641 9.14257 -0.01779656 13.215637 15.224401 15.3911530 8.834038 9.0689108 0.01570562 0.20070833 0.219575 0.221850 0.002275 1.000000e+00 1.786283e-08 FALSE FALSE
MSTRG.14986.2 ENSG00000257103 No_inf pgKDN_inf LSM14A protein_coding   51.11093 54.55342 53.88448 8.516641 9.14257 -0.01779656 1.385991 3.280693 0.8772791 1.727778 0.5199720 -1.89093137 0.02990000 0.073750 0.015950 -0.057800 7.436866e-01 1.786283e-08 FALSE TRUE
MSTRG.14986.3 ENSG00000257103 No_inf pgKDN_inf LSM14A protein_coding   51.11093 54.55342 53.88448 8.516641 9.14257 -0.01779656 7.486183 10.140752 4.4814276 1.114285 1.9316070 -1.17634065 0.15590000 0.200325 0.081325 -0.119000 4.481249e-01 1.786283e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000257103 E001 0.6103171 1.707731e-01 5.947452e-01 0.821764903 19 34172497 34172503 7 + 0.250 0.165 -0.757
ENSG00000257103 E002 2.3435293 2.013673e-01 7.985025e-01 0.924206903 19 34172504 34172524 21 + 0.489 0.549 0.287
ENSG00000257103 E003 6.0055350 6.623297e-02 8.448038e-01 0.944676775 19 34172525 34172567 43 + 0.859 0.830 -0.112
ENSG00000257103 E004 17.9384098 1.446254e-02 8.336885e-01 0.940126157 19 34172568 34172657 90 + 1.265 1.284 0.066
ENSG00000257103 E005 27.6460856 5.026279e-04 1.937298e-01 0.473602828 19 34172658 34172763 106 + 1.493 1.421 -0.248
ENSG00000257103 E006 47.5376212 3.375097e-03 4.872574e-01 0.750828834 19 34194478 34194641 164 + 1.702 1.669 -0.112
ENSG00000257103 E007 0.0000000       19 34195219 34195320 102 +      
ENSG00000257103 E008 0.3722815 1.678147e-02 6.602994e-01   19 34195960 34195994 35 + 0.100 0.165 0.828
ENSG00000257103 E009 40.7029204 3.903760e-04 6.925793e-02 0.265937435 19 34196634 34196763 130 + 1.662 1.579 -0.284
ENSG00000257103 E010 2.0977150 1.149090e-01 7.522372e-01 0.902416916 19 34208196 34208928 733 + 0.450 0.519 0.344
ENSG00000257103 E011 39.3009333 3.676926e-04 7.873639e-03 0.068400043 19 34208929 34209051 123 + 1.667 1.543 -0.423
ENSG00000257103 E012 37.7722148 3.932907e-04 5.514495e-02 0.233930150 19 34215124 34215300 177 + 1.634 1.543 -0.312
ENSG00000257103 E013 19.6016178 7.255990e-04 1.203768e-01 0.366994163 19 34215596 34215661 66 + 1.252 1.356 0.361
ENSG00000257103 E014 45.6362368 3.221771e-04 8.275382e-01 0.937577644 19 34219391 34219573 183 + 1.672 1.663 -0.032
ENSG00000257103 E015 11.5753373 1.954924e-02 4.646210e-01 0.734046207 19 34219706 34219708 3 + 1.057 1.129 0.261
ENSG00000257103 E016 63.3443627 2.543877e-04 8.117076e-01 0.930707718 19 34219709 34219877 169 + 1.802 1.811 0.030
ENSG00000257103 E017 0.0000000       19 34221350 34221506 157 +      
ENSG00000257103 E018 85.8394345 4.571006e-04 5.461932e-01 0.792019797 19 34221507 34221738 232 + 1.947 1.928 -0.064
ENSG00000257103 E019 0.2537694 1.598367e-02 2.860356e-01   19 34221739 34221779 41 + 0.000 0.165 9.357
ENSG00000257103 E020 13.1432273 6.398465e-03 1.742069e-02 0.115696029 19 34226408 34226464 57 + 1.246 1.047 -0.712
ENSG00000257103 E021 23.7761272 6.911500e-04 4.924695e-01 0.754620891 19 34227365 34227368 4 + 1.414 1.373 -0.142
ENSG00000257103 E022 367.6971078 7.384888e-05 8.886183e-05 0.002157775 19 34227369 34229288 1920 + 2.538 2.586 0.160

Help

Please Click HERE to learn more details about the results from DEXseq.