ENSG00000266028

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000573034 ENSG00000266028 No_inf pgKDN_inf SRGAP2 protein_coding protein_coding 36.91444 46.76122 30.14705 2.232398 1.133605 -0.6331259 6.312461 4.0705840 6.4393110 1.5158889 0.7616723 0.6603694 0.18261667 0.085000 0.212150 0.127150 0.46306795 0.02716449 FALSE  
ENST00000604010 ENSG00000266028 No_inf pgKDN_inf SRGAP2 protein_coding protein_coding 36.91444 46.76122 30.14705 2.232398 1.133605 -0.6331259 1.266156 0.3007286 2.6526309 0.3007286 0.7345611 3.0991253 0.04023333 0.006275 0.089700 0.083425 0.02716449 0.02716449 FALSE  
ENST00000604247 ENSG00000266028 No_inf pgKDN_inf SRGAP2 protein_coding retained_intron 36.91444 46.76122 30.14705 2.232398 1.133605 -0.6331259 3.353064 6.7313155 1.0401941 1.3110981 0.2301630 -2.6823741 0.08264167 0.144225 0.034675 -0.109550 0.05644286 0.02716449    
ENST00000605476 ENSG00000266028 No_inf pgKDN_inf SRGAP2 protein_coding protein_coding 36.91444 46.76122 30.14705 2.232398 1.133605 -0.6331259 3.325220 7.8403983 1.4627805 1.3763701 0.8830487 -2.4142234 0.07775833 0.167500 0.045775 -0.121725 0.27195692 0.02716449 FALSE  
MSTRG.2597.14 ENSG00000266028 No_inf pgKDN_inf SRGAP2 protein_coding   36.91444 46.76122 30.14705 2.232398 1.133605 -0.6331259 5.058354 0.0000000 3.3355895 0.0000000 3.3355895 8.3861166 0.15038333 0.000000 0.099800 0.099800 0.82391222 0.02716449 FALSE  
MSTRG.2597.15 ENSG00000266028 No_inf pgKDN_inf SRGAP2 protein_coding   36.91444 46.76122 30.14705 2.232398 1.133605 -0.6331259 10.069131 14.8563244 11.4404726 1.9986166 3.8154995 -0.3766408 0.27510000 0.317650 0.393800 0.076150 0.97724459 0.02716449 FALSE  
MSTRG.2597.23 ENSG00000266028 No_inf pgKDN_inf SRGAP2 protein_coding   36.91444 46.76122 30.14705 2.232398 1.133605 -0.6331259 2.637392 4.9274797 0.7557752 0.6282848 0.2004200 -2.6887819 0.06594167 0.106375 0.025150 -0.081225 0.07376633 0.02716449 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000266028 E001 0.0000000       1 206203346 206203482 137 +      
ENSG00000266028 E002 0.0000000       1 206203530 206203540 11 +      
ENSG00000266028 E003 0.0000000       1 206203541 206203547 7 +      
ENSG00000266028 E004 0.0000000       1 206203548 206203551 4 +      
ENSG00000266028 E005 0.0000000       1 206203552 206203650 99 +      
ENSG00000266028 E006 0.0000000       1 206203888 206203907 20 +      
ENSG00000266028 E007 0.0000000       1 206203908 206204000 93 +      
ENSG00000266028 E008 0.8895467 0.0245002300 1.967570e-02 1.256589e-01 1 206204001 206205428 1428 + 0.000 0.375 11.259
ENSG00000266028 E009 0.0000000       1 206205429 206205625 197 +      
ENSG00000266028 E010 0.0000000       1 206205626 206205672 47 +      
ENSG00000266028 E011 4.0677861 0.0036983045 7.607845e-01 9.064670e-01 1 206205673 206205908 236 + 0.723 0.674 -0.201
ENSG00000266028 E012 0.1187032 0.0118455969 3.506626e-01   1 206205909 206206037 129 + 0.116 0.000 -12.439
ENSG00000266028 E013 0.1187032 0.0118455969 3.506626e-01   1 206206038 206208229 2192 + 0.116 0.000 -12.439
ENSG00000266028 E014 0.2455571 0.0165824711 7.480490e-01   1 206214505 206214611 107 + 0.116 0.078 -0.642
ENSG00000266028 E015 0.1271363 0.0123190305 8.252159e-01   1 206214723 206214840 118 + 0.000 0.078 10.803
ENSG00000266028 E016 0.0000000       1 206296820 206296869 50 +      
ENSG00000266028 E017 3.2237912 0.1088926463 5.159216e-01 7.717788e-01 1 206303281 206303473 193 + 0.537 0.656 0.528
ENSG00000266028 E018 0.0000000       1 206312148 206312247 100 +      
ENSG00000266028 E019 0.0000000       1 206340877 206340915 39 +      
ENSG00000266028 E020 1.4960544 0.0085546713 2.853876e-01 5.791073e-01 1 206342846 206342900 55 + 0.283 0.441 0.943
ENSG00000266028 E021 0.0000000       1 206342901 206343008 108 +      
ENSG00000266028 E022 5.3037929 0.0030783373 9.714044e-01 9.945278e-01 1 206384014 206384076 63 + 0.792 0.785 -0.029
ENSG00000266028 E023 0.0000000       1 206391382 206391422 41 +      
ENSG00000266028 E024 5.4302999 0.0036723112 8.754979e-01 9.574998e-01 1 206392689 206392723 35 + 0.792 0.799 0.025
ENSG00000266028 E025 11.4064172 0.0012182178 9.580086e-02 3.223271e-01 1 206392724 206392904 181 + 1.169 1.017 -0.549
ENSG00000266028 E026 9.0516552 0.0015836627 2.630831e-02 1.502906e-01 1 206393545 206393673 129 + 1.111 0.895 -0.798
ENSG00000266028 E027 0.0000000       1 206398027 206398188 162 +      
ENSG00000266028 E028 0.0000000       1 206401421 206401423 3 +      
ENSG00000266028 E029 0.0000000       1 206401424 206401645 222 +      
ENSG00000266028 E030 0.0000000       1 206404963 206405248 286 +      
ENSG00000266028 E031 0.0000000       1 206405249 206405350 102 +      
ENSG00000266028 E032 7.1375264 0.0024325421 4.413045e-01 7.168207e-01 1 206406377 206406574 198 + 0.952 0.862 -0.342
ENSG00000266028 E033 2.6203632 0.0054018138 1.255649e-01 3.755667e-01 1 206406575 206409976 3402 + 0.403 0.616 1.036
ENSG00000266028 E034 13.5725626 0.0162779538 8.352077e-01 9.406944e-01 1 206415889 206415973 85 + 1.169 1.138 -0.112
ENSG00000266028 E035 8.7475959 0.0080378424 6.885753e-01 8.717612e-01 1 206419373 206419400 28 + 1.007 0.956 -0.191
ENSG00000266028 E036 8.5916983 0.0217247666 2.816621e-01 5.750069e-01 1 206421250 206421274 25 + 1.045 0.916 -0.477
ENSG00000266028 E037 11.6026211 0.0016825291 6.946417e-03 6.275603e-02 1 206430162 206430222 61 + 1.220 0.983 -0.855
ENSG00000266028 E038 14.3113190 0.0009404425 7.263005e-03 6.469413e-02 1 206436965 206437042 78 + 1.293 1.078 -0.765
ENSG00000266028 E039 0.1186381 0.0118145723 3.506894e-01   1 206437619 206437963 345 + 0.116 0.000 -12.440
ENSG00000266028 E040 25.0958748 0.0006479320 2.097855e-01 4.942155e-01 1 206437964 206438098 135 + 1.455 1.368 -0.301
ENSG00000266028 E041 20.5581146 0.0006506181 3.827030e-01 6.688931e-01 1 206439976 206440060 85 + 1.362 1.293 -0.242
ENSG00000266028 E042 11.9538253 0.0011698029 7.728635e-01 9.125992e-01 1 206440061 206440081 21 + 1.122 1.085 -0.131
ENSG00000266028 E043 38.9676027 0.0003703925 7.059764e-01 8.806771e-01 1 206446075 206446299 225 + 1.607 1.576 -0.106
ENSG00000266028 E044 19.7852696 0.0007038107 4.496326e-01 7.232690e-01 1 206450386 206450465 80 + 1.280 1.318 0.134
ENSG00000266028 E045 0.2542726 0.2427938200 4.819137e-01   1 206453199 206453199 1 + 0.000 0.144 11.119
ENSG00000266028 E046 27.4936377 0.0006232073 7.562184e-01 9.039225e-01 1 206453200 206453380 181 + 1.460 1.429 -0.105
ENSG00000266028 E047 5.3989240 0.0290685937 2.999980e-03 3.450649e-02 1 206453661 206454143 483 + 0.497 0.906 1.721
ENSG00000266028 E048 75.8038212 0.0002169329 8.693793e-02 3.055412e-01 1 206454144 206454877 734 + 1.842 1.888 0.154
ENSG00000266028 E049 37.7711233 0.0009901091 9.776504e-01 9.966761e-01 1 206454878 206455024 147 + 1.583 1.569 -0.049
ENSG00000266028 E050 140.9925746 0.0001329402 5.716094e-05 1.487724e-03 1 206455025 206455772 748 + 2.082 2.168 0.286
ENSG00000266028 E051 55.5938458 0.0003187340 4.290852e-04 7.734988e-03 1 206455773 206456292 520 + 1.651 1.784 0.451
ENSG00000266028 E052 16.7328365 0.0074182590 2.283171e-10 2.187221e-08 1 206457278 206458370 1093 + 0.792 1.375 2.129
ENSG00000266028 E053 1.9949679 0.0137120346 2.245616e-01 5.120786e-01 1 206458371 206458409 39 + 0.347 0.525 0.943
ENSG00000266028 E054 4.4952805 0.0033490311 2.657254e-02 1.511120e-01 1 206458410 206458622 213 + 0.537 0.812 1.165
ENSG00000266028 E055 16.4322559 0.0013256301 6.441777e-02 2.557083e-01 1 206458623 206458947 325 + 1.313 1.168 -0.513
ENSG00000266028 E056 1.3685400 0.0162568433 3.944117e-01 6.792107e-01 1 206459585 206459679 95 + 0.283 0.410 0.773
ENSG00000266028 E057 200.7082902 0.0052694133 4.706685e-04 8.328424e-03 1 206461037 206464436 3400 + 2.361 2.242 -0.398

Help

Please Click HERE to learn more details about the results from DEXseq.