ENSG00000266094

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000577571 ENSG00000266094 No_inf pgKDN_inf RASSF5 protein_coding protein_coding 59.43082 44.31299 60.9723 0.4981402 0.759796 0.4603352 34.282656 20.6563701 41.767232 0.8358824 2.1639087 1.0154319 0.56822500 0.466075 0.685200 0.219125 0.010235404 0.001121339 FALSE TRUE
ENST00000579436 ENSG00000266094 No_inf pgKDN_inf RASSF5 protein_coding protein_coding 59.43082 44.31299 60.9723 0.4981402 0.759796 0.4603352 4.795495 0.3190573 5.599230 0.1842370 0.6665440 4.0913919 0.07157500 0.007300 0.091725 0.084425 0.001121339 0.001121339 FALSE TRUE
ENST00000579942 ENSG00000266094 No_inf pgKDN_inf RASSF5 protein_coding retained_intron 59.43082 44.31299 60.9723 0.4981402 0.759796 0.4603352 3.660287 3.0123048 3.238654 0.4269174 0.4541356 0.1041928 0.06190833 0.067800 0.053125 -0.014675 0.861704220 0.001121339 TRUE FALSE
ENST00000605653 ENSG00000266094 No_inf pgKDN_inf RASSF5 protein_coding retained_intron 59.43082 44.31299 60.9723 0.4981402 0.759796 0.4603352 12.156671 17.5610165 7.687500 0.2461871 3.6891188 -1.1907358 0.22497500 0.396450 0.125200 -0.271250 0.194998643 0.001121339 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000266094 E001 0.2356421 1.562155e-02 3.447510e-01   1 206507531 206507545 15 + 0.156 0.000 -9.377
ENSG00000266094 E002 0.8279553 1.274583e-02 1.129505e-02 8.715127e-02 1 206507546 206507594 49 + 0.399 0.000 -12.697
ENSG00000266094 E003 5.0979958 3.425543e-03 8.287821e-09 5.983873e-07 1 206507595 206508059 465 + 0.993 0.192 -3.988
ENSG00000266094 E004 0.0000000       1 206518388 206518544 157 +      
ENSG00000266094 E005 2.1305905 8.699539e-03 3.177153e-04 6.089430e-03 1 206538172 206538293 122 + 0.668 0.107 -3.718
ENSG00000266094 E006 30.0730227 8.092313e-04 2.986451e-02 1.625830e-01 1 206557165 206557560 396 + 1.542 1.420 -0.417
ENSG00000266094 E007 29.0025489 5.290603e-04 6.516258e-02 2.570539e-01 1 206557561 206557693 133 + 1.520 1.416 -0.358
ENSG00000266094 E008 0.0000000       1 206583120 206583268 149 +      
ENSG00000266094 E009 11.9277620 2.218217e-03 2.129549e-03 2.679148e-02 1 206583269 206583271 3 + 1.212 0.944 -0.973
ENSG00000266094 E010 33.0174881 4.611110e-03 9.003381e-02 3.116420e-01 1 206583272 206583379 108 + 1.573 1.472 -0.345
ENSG00000266094 E011 0.3709916 1.654726e-02 4.352507e-01   1 206583380 206583695 316 + 0.085 0.192 1.369
ENSG00000266094 E012 34.3369294 5.553660e-04 4.890003e-01 7.520744e-01 1 206584387 206584474 88 + 1.563 1.526 -0.127
ENSG00000266094 E013 57.1476019 1.082644e-03 6.242952e-03 5.809432e-02 1 206584475 206584684 210 + 1.811 1.696 -0.389
ENSG00000266094 E014 6.8600365 2.040857e-03 3.359685e-01 6.278459e-01 1 206584685 206585179 495 + 0.847 0.944 0.369
ENSG00000266094 E015 33.9192537 5.703819e-04 3.686557e-03 4.013540e-02 1 206585180 206585295 116 + 1.604 1.451 -0.524
ENSG00000266094 E016 15.2359331 9.531370e-04 1.880394e-06 8.068190e-05 1 206585296 206586825 1530 + 1.011 1.367 1.265
ENSG00000266094 E017 746.9925867 7.162192e-05 3.421480e-09 2.647548e-07 1 206586826 206589448 2623 + 2.857 2.889 0.107

Help

Please Click HERE to learn more details about the results from DEXseq.