ENSG00000272758

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000608015 ENSG00000272758 No_inf pgKDN_inf WDR5B-DT lncRNA lncRNA 19.24847 16.58029 20.43673 2.172352 1.163552 0.3015313 15.068832 8.161004 18.3478405 1.3170264 0.8243674 1.167811 0.77404167 0.515850 0.901975 0.386125 0.00572705 0.00572705   FALSE
ENST00000667395 ENSG00000272758 No_inf pgKDN_inf WDR5B-DT lncRNA lncRNA 19.24847 16.58029 20.43673 2.172352 1.163552 0.3015313 1.393853 3.287820 0.6852273 0.6993418 0.6852273 -2.245956 0.08201667 0.206375 0.029775 -0.176600 0.06459541 0.00572705   FALSE
ENST00000686885 ENSG00000272758 No_inf pgKDN_inf WDR5B-DT lncRNA lncRNA 19.24847 16.58029 20.43673 2.172352 1.163552 0.3015313 1.519544 4.558632 0.0000000 2.8235733 0.0000000 -8.835618 0.07800000 0.234000 0.000000 -0.234000 0.43478206 0.00572705   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000272758 E001 0.0000000       3 122416200 122416204 5 +      
ENSG00000272758 E002 0.0000000       3 122416205 122416206 2 +      
ENSG00000272758 E003 0.2539903 0.018025135 0.852193340   3 122416207 122416218 12 + 0.000 0.143 10.960
ENSG00000272758 E004 0.5076336 0.016960120 0.290181966 0.58380611 3 122416219 122416224 6 + 0.000 0.250 13.105
ENSG00000272758 E005 0.6347699 0.016594029 0.180416120 0.45591761 3 122416225 122416250 26 + 0.000 0.295 13.381
ENSG00000272758 E006 0.5082629 0.020491096 0.294662359 0.58795752 3 122420986 122420988 3 + 0.000 0.250 13.104
ENSG00000272758 E007 2.1218558 0.007563636 0.525195626 0.77805584 3 122420989 122421190 202 + 0.349 0.547 1.034
ENSG00000272758 E008 1.8494256 0.125310868 0.534128557 0.78433457 3 122421191 122421404 214 + 0.455 0.439 -0.082
ENSG00000272758 E009 0.0000000       3 122425607 122425658 52 +      
ENSG00000272758 E010 0.0000000       3 122425848 122426132 285 +      
ENSG00000272758 E011 0.1265070 0.013408267 1.000000000   3 122426133 122427240 1108 + 0.000 0.077 11.479
ENSG00000272758 E012 0.4889073 0.019644801 0.342983020   3 122432467 122432521 55 + 0.209 0.143 -0.667
ENSG00000272758 E013 0.9596246 0.019302674 0.004352943 0.04500127 3 122432786 122433262 477 + 0.455 0.143 -2.252
ENSG00000272758 E014 0.1265070 0.013408267 1.000000000   3 122442727 122443180 454 + 0.000 0.077 11.479

Help

Please Click HERE to learn more details about the results from DEXseq.