ENSG00000275052

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000470801 ENSG00000275052 No_inf pgKDN_inf PPP4R3B protein_coding protein_coding_CDS_not_defined 41.78563 33.92315 50.67323 1.061499 3.398722 0.5788131 2.998373 0.0000000 4.984453 0.0000000 2.2931998 8.9641830 0.05885000 0.000000 0.090650 0.090650 0.04019086 0.04019086    
ENST00000611717 ENSG00000275052 No_inf pgKDN_inf PPP4R3B protein_coding protein_coding 41.78563 33.92315 50.67323 1.061499 3.398722 0.5788131 6.775289 5.4961113 6.535160 1.9103155 3.8339597 0.2493946 0.16351667 0.167400 0.117950 -0.049450 0.82299884 0.04019086 FALSE  
ENST00000616288 ENSG00000275052 No_inf pgKDN_inf PPP4R3B protein_coding protein_coding 41.78563 33.92315 50.67323 1.061499 3.398722 0.5788131 1.765130 0.4782813 3.109148 0.4782813 1.8411001 2.6753676 0.04182500 0.012925 0.067850 0.054925 0.82691705 0.04019086 FALSE  
ENST00000616407 ENSG00000275052 No_inf pgKDN_inf PPP4R3B protein_coding protein_coding 41.78563 33.92315 50.67323 1.061499 3.398722 0.5788131 1.505849 0.0000000 4.517548 0.0000000 2.6255858 8.8225860 0.03344167 0.000000 0.100325 0.100325 0.56545007 0.04019086 FALSE  
MSTRG.16300.1 ENSG00000275052 No_inf pgKDN_inf PPP4R3B protein_coding   41.78563 33.92315 50.67323 1.061499 3.398722 0.5788131 2.353418 4.7753491 1.337609 1.5230057 0.8247774 -1.8282218 0.06407500 0.137400 0.028950 -0.108450 0.26331484 0.04019086 FALSE  
MSTRG.16300.7 ENSG00000275052 No_inf pgKDN_inf PPP4R3B protein_coding   41.78563 33.92315 50.67323 1.061499 3.398722 0.5788131 23.220990 21.1745571 27.447533 0.5532394 1.6653346 0.3741890 0.56373333 0.624625 0.543150 -0.081475 0.51983764 0.04019086 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000275052 E001 0.1268540 0.0123266775 4.277907e-01   2 55547177 55547291 115 - 0.000 0.105 8.666
ENSG00000275052 E002 57.5954533 0.0018947749 6.077728e-05 0.001558933 2 55547292 55548377 1086 - 1.680 1.850 0.573
ENSG00000275052 E003 308.2789676 0.0003884292 2.917008e-02 0.160242330 2 55548378 55550006 1629 - 2.473 2.507 0.115
ENSG00000275052 E004 55.7155052 0.0003907686 2.232001e-01 0.510713652 2 55558775 55558968 194 - 1.729 1.779 0.168
ENSG00000275052 E005 48.9731545 0.0003512201 4.064168e-01 0.689103277 2 55564313 55564476 164 - 1.680 1.717 0.124
ENSG00000275052 E006 11.3481021 0.0014434872 7.158025e-01 0.885420265 2 55564477 55564497 21 - 1.076 1.108 0.115
ENSG00000275052 E007 37.5867084 0.0004102928 2.965496e-01 0.589731422 2 55564902 55565041 140 - 1.607 1.558 -0.167
ENSG00000275052 E008 0.4997349 0.0250175804 2.250503e-01   2 55568029 55568193 165 - 0.086 0.261 1.918
ENSG00000275052 E009 40.6473765 0.0003618190 3.654136e-01 0.653975959 2 55568194 55568363 170 - 1.637 1.596 -0.138
ENSG00000275052 E010 30.6110573 0.0166987254 8.051128e-01 0.927860699 2 55573619 55573777 159 - 1.505 1.491 -0.049
ENSG00000275052 E011 18.3519361 0.0078763890 1.874412e-01 0.465573042 2 55577315 55577356 42 - 1.328 1.229 -0.349
ENSG00000275052 E012 16.0044235 0.0028995744 4.879069e-02 0.217657932 2 55578247 55578342 96 - 1.291 1.143 -0.522
ENSG00000275052 E013 22.0072236 0.0137242067 2.734309e-01 0.567178953 2 55579679 55579781 103 - 1.398 1.312 -0.299
ENSG00000275052 E014 32.9299797 0.0004123146 9.746197e-01 0.995411363 2 55581567 55581698 132 - 1.528 1.531 0.011
ENSG00000275052 E015 32.3565257 0.0004441853 4.971034e-01 0.757887359 2 55585051 55585167 117 - 1.505 1.541 0.125
ENSG00000275052 E016 24.9554872 0.0006420149 5.820122e-01 0.813872283 2 55586618 55586734 117 - 1.427 1.396 -0.107
ENSG00000275052 E017 17.1373718 0.0009007110 2.021419e-01 0.484612978 2 55588879 55588956 78 - 1.296 1.207 -0.312
ENSG00000275052 E018 0.2459004 0.0164846035 8.606870e-01   2 55591505 55591531 27 - 0.086 0.105 0.333
ENSG00000275052 E019 26.3677712 0.0005271301 1.592982e-01 0.426619570 2 55598416 55598697 282 - 1.471 1.391 -0.275
ENSG00000275052 E020 34.9414045 0.0004089020 1.772326e-02 0.117157304 2 55598698 55599039 342 - 1.605 1.487 -0.404
ENSG00000275052 E021 19.7359559 0.0007272952 9.556501e-03 0.078067160 2 55603978 55604076 99 - 1.386 1.214 -0.601
ENSG00000275052 E022 3.6904506 0.0055742096 1.845813e-01 0.461744398 2 55614176 55615450 1275 - 0.584 0.754 0.720
ENSG00000275052 E023 13.5885368 0.0011851992 1.449415e-01 0.405292263 2 55615451 55615506 56 - 1.211 1.098 -0.404
ENSG00000275052 E024 0.9786657 0.0122134311 7.509890e-01 0.901794187 2 55616518 55616617 100 - 0.272 0.322 0.333
ENSG00000275052 E025 38.9804509 0.0004707326 4.883367e-02 0.217686998 2 55617144 55617978 835 - 1.641 1.548 -0.316
ENSG00000275052 E026 1.9888063 0.2419656186 1.475050e-01 0.408877755 2 55618066 55618880 815 - 0.320 0.604 1.469

Help

Please Click HERE to learn more details about the results from DEXseq.