ENSG00000275066

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000612223 ENSG00000275066 No_inf pgKDN_inf SYNRG protein_coding protein_coding 10.17604 9.031653 10.93986 0.7672655 0.3827597 0.2762538 6.4328425 7.2884929 6.3896449 0.2301075 0.2188101 -0.1896067 0.64622500 0.821775 0.584850 -0.236925 2.105096e-01 9.754398e-05 FALSE TRUE
ENST00000612641 ENSG00000275066 No_inf pgKDN_inf SYNRG protein_coding protein_coding_CDS_not_defined 10.17604 9.031653 10.93986 0.7672655 0.3827597 0.2762538 0.2031656 0.6094967 0.0000000 0.6094967 0.0000000 -5.9530246 0.01812500 0.054375 0.000000 -0.054375 8.346783e-01 9.754398e-05   FALSE
ENST00000616179 ENSG00000275066 No_inf pgKDN_inf SYNRG protein_coding protein_coding 10.17604 9.031653 10.93986 0.7672655 0.3827597 0.2762538 1.6950087 0.0000000 2.5476299 0.0000000 0.5227474 7.9986637 0.15989167 0.000000 0.229625 0.229625 9.754398e-05 9.754398e-05 FALSE TRUE
MSTRG.12568.3 ENSG00000275066 No_inf pgKDN_inf SYNRG protein_coding   10.17604 9.031653 10.93986 0.7672655 0.3827597 0.2762538 0.4777727 0.0000000 0.8389979 0.0000000 0.3512341 6.4076890 0.04251667 0.000000 0.075450 0.075450 1.745504e-01 9.754398e-05 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000275066 E001 0.7618760 0.0131366182 7.516411e-03 6.627271e-02 17 37514807 37514889 83 - 0.000 0.402 12.398
ENSG00000275066 E002 27.2463522 0.0005934400 1.458781e-03 2.000964e-02 17 37514890 37515444 555 - 1.351 1.532 0.623
ENSG00000275066 E003 8.4966423 0.0040823656 1.163624e-01 3.596909e-01 17 37515445 37515568 124 - 0.894 1.048 0.573
ENSG00000275066 E004 68.1526363 0.0018501636 1.221957e-09 1.021783e-07 17 37515569 37517080 1512 - 1.709 1.940 0.779
ENSG00000275066 E005 4.6234241 0.0029593872 1.913203e-04 4.037038e-03 17 37517081 37517186 106 - 0.460 0.923 1.967
ENSG00000275066 E006 26.2040082 0.0008675080 3.843391e-05 1.064661e-03 17 37517187 37517829 643 - 1.298 1.538 0.831
ENSG00000275066 E007 26.8244043 0.0006058935 1.482649e-02 1.042435e-01 17 37517830 37518460 631 - 1.369 1.509 0.481
ENSG00000275066 E008 34.2463018 0.0008480181 8.834580e-01 9.608281e-01 17 37518461 37518886 426 - 1.549 1.545 -0.015
ENSG00000275066 E009 16.0521253 0.0020448861 9.274907e-02 3.162512e-01 17 37518887 37519009 123 - 1.287 1.168 -0.422
ENSG00000275066 E010 12.1976423 0.0013192345 5.099767e-01 7.675713e-01 17 37519010 37519071 62 - 1.145 1.095 -0.181
ENSG00000275066 E011 6.8126407 0.0019828623 2.806997e-01 5.739317e-01 17 37520179 37520214 36 - 0.943 0.835 -0.412
ENSG00000275066 E012 12.5199780 0.0012085238 5.378902e-02 2.307604e-01 17 37520538 37520648 111 - 1.200 1.048 -0.547
ENSG00000275066 E013 0.1271363 0.0123404755 5.025918e-01   17 37529783 37529851 69 - 0.000 0.098 12.586
ENSG00000275066 E014 12.6887910 0.0018897370 4.116828e-01 6.932157e-01 17 37535979 37536085 107 - 1.166 1.104 -0.226
ENSG00000275066 E015 6.6701791 0.0020490135 7.628169e-02 2.822994e-01 17 37536086 37536127 42 - 0.966 0.784 -0.699
ENSG00000275066 E016 1.3795885 0.0093961241 2.259408e-02 1.367818e-01 17 37536128 37537478 1351 - 0.168 0.517 2.279
ENSG00000275066 E017 10.8901942 0.0039725653 2.723867e-03 3.205521e-02 17 37538324 37538420 97 - 1.187 0.923 -0.964
ENSG00000275066 E018 7.2672586 0.0086056664 2.643662e-02 1.506770e-01 17 37539192 37539245 54 - 1.018 0.784 -0.891
ENSG00000275066 E019 7.5388656 0.0019029397 2.094173e-01 4.937148e-01 17 37540380 37540480 101 - 0.988 0.867 -0.457
ENSG00000275066 E020 6.2051020 0.0022910167 3.102746e-01 6.034964e-01 17 37540481 37540543 63 - 0.907 0.802 -0.406
ENSG00000275066 E021 1.8474071 0.1189498404 4.317209e-01 7.093343e-01 17 37540626 37541971 1346 - 0.383 0.517 0.695
ENSG00000275066 E022 27.2006673 0.0006023612 2.371694e-01 5.261381e-01 17 37541972 37542427 456 - 1.480 1.418 -0.216
ENSG00000275066 E023 4.0439397 0.0036088399 7.134221e-01 8.845101e-01 17 37542428 37542430 3 - 0.679 0.726 0.196
ENSG00000275066 E024 9.3341919 0.0060095458 3.478511e-01 6.383899e-01 17 37542431 37542565 135 - 0.966 1.058 0.337
ENSG00000275066 E025 16.5634082 0.0010244246 1.345538e-01 3.899950e-01 17 37553115 37553415 301 - 1.293 1.190 -0.362
ENSG00000275066 E026 25.7240860 0.0005604456 2.129613e-01 4.981505e-01 17 37553416 37553986 571 - 1.460 1.392 -0.235
ENSG00000275066 E027 5.1347663 0.0030437290 9.297074e-01 9.793714e-01 17 37553987 37554059 73 - 0.791 0.784 -0.029
ENSG00000275066 E028 0.0000000       17 37557140 37557203 64 -      
ENSG00000275066 E029 3.9976220 0.0053706585 1.738267e-01 4.472824e-01 17 37561195 37561257 63 - 0.775 0.607 -0.699
ENSG00000275066 E030 6.5503512 0.0110528141 1.922931e-01 4.722523e-01 17 37561471 37561589 119 - 0.943 0.802 -0.543
ENSG00000275066 E031 0.8809261 0.0138882967 4.105963e-02 1.966508e-01 17 37566849 37568790 1942 - 0.092 0.402 2.694
ENSG00000275066 E032 7.6224234 0.0032378352 1.823024e-02 1.192576e-01 17 37568791 37568924 134 - 1.037 0.802 -0.891
ENSG00000275066 E033 9.0605406 0.0021904550 2.151918e-03 2.698851e-02 17 37570637 37570885 249 - 1.122 0.835 -1.068
ENSG00000275066 E034 2.9149978 0.0140314800 3.068634e-01 6.001294e-01 17 37571791 37571832 42 - 0.657 0.517 -0.628
ENSG00000275066 E035 6.4548730 0.0111718930 3.528806e-01 6.428253e-01 17 37571833 37571987 155 - 0.919 0.819 -0.386
ENSG00000275066 E036 3.6846571 0.0038845598 5.853127e-01 8.158016e-01 17 37576341 37576418 78 - 0.633 0.705 0.301
ENSG00000275066 E037 0.1272623 0.0123187821 5.026944e-01   17 37576419 37576480 62 - 0.000 0.098 12.587
ENSG00000275066 E038 3.6361853 0.0045172964 2.043241e-01 4.871803e-01 17 37577380 37577446 67 - 0.739 0.579 -0.680
ENSG00000275066 E039 7.9685147 0.0020203772 7.022124e-03 6.316398e-02 17 37577447 37577613 167 - 1.065 0.802 -0.991
ENSG00000275066 E040 2.6676000 0.0058978727 2.650406e-01 5.581032e-01 17 37579132 37579434 303 - 0.633 0.482 -0.699
ENSG00000275066 E041 0.2357071 0.0157369023 2.665407e-01   17 37584322 37584647 326 - 0.168 0.000 -14.250
ENSG00000275066 E042 5.6608332 0.0026515373 4.169668e-03 4.375295e-02 17 37584648 37584759 112 - 0.955 0.634 -1.278
ENSG00000275066 E043 2.0422645 0.0067047109 3.755686e-02 1.868283e-01 17 37585325 37585341 17 - 0.609 0.305 -1.592
ENSG00000275066 E044 3.6094277 0.0043239228 1.673177e-02 1.127873e-01 17 37585342 37585430 89 - 0.791 0.482 -1.351
ENSG00000275066 E045 3.5100540 0.0040861682 1.372212e-01 3.943199e-01 17 37586419 37586549 131 - 0.739 0.549 -0.817
ENSG00000275066 E046 2.9296020 0.0051793965 8.115408e-01 9.306278e-01 17 37596223 37596341 119 - 0.609 0.579 -0.132
ENSG00000275066 E047 0.7336439 0.0355212327 9.372242e-01 9.820871e-01 17 37596342 37596344 3 - 0.232 0.246 0.109
ENSG00000275066 E048 1.7248666 0.0079044500 5.127299e-01 7.696942e-01 17 37600363 37600403 41 - 0.383 0.482 0.524
ENSG00000275066 E049 0.3543453 0.0158128939 1.168384e-01   17 37600404 37600988 585 - 0.232 0.000 -14.777
ENSG00000275066 E050 1.7167158 0.0136394559 9.018079e-01 9.684815e-01 17 37609279 37609367 89 - 0.423 0.444 0.109
ENSG00000275066 E051 0.4720409 0.0163022134 5.275828e-02   17 37609368 37609472 105 - 0.288 0.000 -15.139

Help

Please Click HERE to learn more details about the results from DEXseq.