ENSG00000276600

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000617070 ENSG00000276600 No_inf pgKDN_inf RAB7B protein_coding protein_coding 32.63283 33.76105 33.05719 0.6041797 1.029488 -0.03038676 27.746661 28.421190 29.993616 0.7481464 0.3775433 0.07766192 0.85053333 0.843600 0.909 0.065400 0.52833471 0.00709304 FALSE  
ENST00000622969 ENSG00000276600 No_inf pgKDN_inf RAB7B protein_coding protein_coding 32.63283 33.76105 33.05719 0.6041797 1.029488 -0.03038676 3.496495 3.338083 3.063572 0.8056979 0.7450952 -0.12341893 0.10674167 0.097675 0.091 -0.006675 0.99538756 0.00709304 FALSE  
MSTRG.2586.1 ENSG00000276600 No_inf pgKDN_inf RAB7B protein_coding   32.63283 33.76105 33.05719 0.6041797 1.029488 -0.03038676 1.348452 1.878111 0.000000 0.7166602 0.0000000 -7.56079953 0.04150833 0.055075 0.000 -0.055075 0.00709304 0.00709304 TRUE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000276600 E001 0.379868 0.0280990560 0.1354521242   1 205976657 205976739 83 - 0.000 0.227 10.553
ENSG00000276600 E002 0.000000       1 205976740 205976740 1 -      
ENSG00000276600 E003 65.690132 0.0028047667 0.2241569027 0.51173759 1 205976741 205977258 518 - 1.793 1.843 0.168
ENSG00000276600 E004 80.700942 0.0002396080 0.1174190217 0.36196145 1 205977259 205977698 440 - 1.881 1.932 0.171
ENSG00000276600 E005 38.553326 0.0003900058 0.9218288884 0.97574057 1 205977699 205977926 228 - 1.592 1.597 0.020
ENSG00000276600 E006 178.990210 0.0001324069 0.5785597290 0.81164738 1 205977927 205978928 1002 - 2.246 2.258 0.039
ENSG00000276600 E007 6.050394 0.0162512334 0.3183749990 0.61111955 1 205983743 205984204 462 - 0.777 0.895 0.458
ENSG00000276600 E008 39.340745 0.0018098598 0.3313343057 0.62359016 1 205985540 205985665 126 - 1.628 1.582 -0.156
ENSG00000276600 E009 54.228367 0.0002889183 0.0008369753 0.01306932 1 205992480 205992695 216 - 1.806 1.677 -0.435
ENSG00000276600 E010 27.911118 0.0005170639 0.1749754681 0.44880372 1 205993420 205993546 127 - 1.498 1.424 -0.252
ENSG00000276600 E011 16.219800 0.0011681923 0.8183906874 0.93393975 1 205994083 205994151 69 - 1.224 1.241 0.062
ENSG00000276600 E012 0.000000       1 205994152 205994439 288 -      
ENSG00000276600 E013 20.902391 0.0007604582 0.6469479625 0.85062144 1 206003253 206003476 224 - 1.321 1.351 0.106

Help

Please Click HERE to learn more details about the results from DEXseq.