ENSG00000008294

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262013 ENSG00000008294 pgwt_inf pgKDN_inf SPAG9 protein_coding protein_coding 41.70492 44.64414 50.09434 1.91228 2.850792 0.1661416 4.083623 3.255376 3.512261 0.8507829 1.3156675 0.10925245 0.10906667 0.071650 0.072525 0.000875 1.000000e+00 2.456077e-06 FALSE TRUE
ENST00000357122 ENSG00000008294 pgwt_inf pgKDN_inf SPAG9 protein_coding protein_coding 41.70492 44.64414 50.09434 1.91228 2.850792 0.1661416 9.586925 14.217347 14.543428 1.3984379 1.4821314 0.03269233 0.20510000 0.321775 0.293525 -0.028250 9.335409e-01 2.456077e-06 FALSE TRUE
MSTRG.12946.10 ENSG00000008294 pgwt_inf pgKDN_inf SPAG9 protein_coding   41.70492 44.64414 50.09434 1.91228 2.850792 0.1661416 3.314174 4.906684 0.000000 0.8080950 0.0000000 -8.94154174 0.09268333 0.110425 0.000000 -0.110425 2.456077e-06 2.456077e-06 TRUE TRUE
MSTRG.12946.11 ENSG00000008294 pgwt_inf pgKDN_inf SPAG9 protein_coding   41.70492 44.64414 50.09434 1.91228 2.850792 0.1661416 1.242149 0.000000 3.726447 0.0000000 2.1622260 8.54552313 0.02372500 0.000000 0.071175 0.071175 8.293702e-01 2.456077e-06 TRUE TRUE
MSTRG.12946.13 ENSG00000008294 pgwt_inf pgKDN_inf SPAG9 protein_coding   41.70492 44.64414 50.09434 1.91228 2.850792 0.1661416 5.021122 4.378033 6.529414 1.5806007 0.8795242 0.57558718 0.12039167 0.094825 0.132100 0.037275 8.869824e-01 2.456077e-06 FALSE TRUE
MSTRG.12946.2 ENSG00000008294 pgwt_inf pgKDN_inf SPAG9 protein_coding   41.70492 44.64414 50.09434 1.91228 2.850792 0.1661416 6.944866 6.593605 11.200676 0.6948140 0.8510765 0.76354754 0.15845833 0.150150 0.223100 0.072950 8.482075e-01 2.456077e-06 FALSE TRUE
MSTRG.12946.4 ENSG00000008294 pgwt_inf pgKDN_inf SPAG9 protein_coding   41.70492 44.64414 50.09434 1.91228 2.850792 0.1661416 4.813136 3.803679 4.666613 0.9756941 1.6367465 0.29428065 0.12815833 0.086700 0.098600 0.011900 1.000000e+00 2.456077e-06 TRUE TRUE
MSTRG.12946.5 ENSG00000008294 pgwt_inf pgKDN_inf SPAG9 protein_coding   41.70492 44.64414 50.09434 1.91228 2.850792 0.1661416 2.305216 2.531642 1.309324 0.8889538 0.9080751 -0.94596220 0.05993333 0.056750 0.023675 -0.033075 8.869824e-01 2.456077e-06 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000008294 E001 0.0000000       17 50962174 50962175 2 -      
ENSG00000008294 E002 0.4834952 3.074332e-02 0.3011147051   17 50962176 50962199 24 - 0.094 0.244 1.646
ENSG00000008294 E003 0.4834952 3.074332e-02 0.3011147051   17 50962200 50962202 3 - 0.094 0.244 1.646
ENSG00000008294 E004 203.4671006 1.719411e-03 0.0084927781 0.32690235 17 50962203 50964148 1946 - 2.341 2.271 -0.233
ENSG00000008294 E005 26.3305182 6.134292e-04 0.3074434323 0.87553922 17 50964149 50964394 246 - 1.408 1.465 0.196
ENSG00000008294 E006 41.0234941 3.659656e-04 0.5783655198 0.94142672 17 50964395 50965059 665 - 1.635 1.607 -0.095
ENSG00000008294 E007 5.2429679 2.820189e-03 0.0909144284 0.68770933 17 50965060 50965074 15 - 0.876 0.679 -0.787
ENSG00000008294 E008 45.5177178 3.423457e-04 0.3150941309 0.87839425 17 50965075 50965626 552 - 1.688 1.641 -0.159
ENSG00000008294 E009 7.9885685 4.807787e-02 0.5429945291 0.93514816 17 50965627 50965643 17 - 0.916 0.991 0.283
ENSG00000008294 E010 194.2494112 8.583487e-05 0.0741016836 0.65457618 17 50965644 50966299 656 - 2.273 2.308 0.118
ENSG00000008294 E011 36.7471470 1.183064e-02 0.3814347595 0.89981940 17 50966300 50966387 88 - 1.603 1.544 -0.202
ENSG00000008294 E012 50.2439070 8.570818e-03 0.7689287669 0.97359101 17 50970707 50970856 150 - 1.717 1.699 -0.059
ENSG00000008294 E013 44.0883936 3.055331e-03 0.7500631410 0.97034666 17 50974771 50974869 99 - 1.661 1.644 -0.060
ENSG00000008294 E014 38.9810260 1.698358e-03 0.8556439473 0.98559583 17 50974870 50974947 78 - 1.598 1.605 0.025
ENSG00000008294 E015 36.7015338 5.012853e-04 0.0007000096 0.08906855 17 50974948 50975862 915 - 1.490 1.656 0.566
ENSG00000008294 E016 11.3166003 7.223367e-03 0.5531541562 0.93727038 17 50975863 50975901 39 - 1.065 1.116 0.187
ENSG00000008294 E017 26.5440917 1.188448e-02 0.2496902222 0.84579545 17 50975902 50976599 698 - 1.400 1.480 0.275
ENSG00000008294 E018 20.1044482 1.637053e-02 0.1515080746 0.77378825 17 50976600 50977107 508 - 1.264 1.383 0.415
ENSG00000008294 E019 36.6821109 7.528432e-04 0.3925888825 0.90102245 17 50977108 50977221 114 - 1.556 1.597 0.139
ENSG00000008294 E020 16.0273215 1.128452e-03 0.7912562449 0.97846580 17 50979746 50979761 16 - 1.222 1.239 0.061
ENSG00000008294 E021 45.6024034 1.091151e-03 0.5922028965 0.94375317 17 50979762 50979917 156 - 1.657 1.679 0.077
ENSG00000008294 E022 50.3469536 1.439163e-03 0.9417195412 0.99581299 17 50982524 50982672 149 - 1.709 1.710 0.005
ENSG00000008294 E023 35.7830726 7.549274e-04 0.8696881766 0.98753939 17 50984923 50984990 68 - 1.562 1.568 0.021
ENSG00000008294 E024 21.7832899 6.404726e-04 0.3749896228 0.89843081 17 50985698 50985698 1 - 1.383 1.325 -0.202
ENSG00000008294 E025 35.2171201 4.205540e-04 0.6255224043 0.94835971 17 50985699 50985778 80 - 1.570 1.544 -0.091
ENSG00000008294 E026 39.9870827 3.715506e-04 0.9841296011 0.99796923 17 50987112 50987237 126 - 1.613 1.610 -0.010
ENSG00000008294 E027 0.1293601 1.237240e-02 0.5638921835   17 50989540 50989638 99 - 0.094 0.000 -11.931
ENSG00000008294 E028 0.5052373 1.536721e-02 0.3426464481   17 50989639 50989676 38 - 0.236 0.097 -1.524
ENSG00000008294 E029 49.4721975 3.067488e-04 0.9026775189 0.99138449 17 50989677 50989827 151 - 1.701 1.704 0.011
ENSG00000008294 E030 23.1844782 4.718108e-03 0.0917826036 0.68926007 17 50989828 50989872 45 - 1.327 1.438 0.383
ENSG00000008294 E031 0.0000000       17 50990023 50990164 142 -      
ENSG00000008294 E032 0.1293535 1.237311e-02 0.5638412826   17 50990327 50990449 123 - 0.094 0.000 -11.931
ENSG00000008294 E033 56.2382244 3.744572e-04 0.1658743734 0.78625761 17 50990450 50990668 219 - 1.731 1.784 0.181
ENSG00000008294 E034 0.0000000       17 50990669 50990742 74 -      
ENSG00000008294 E035 12.2548351 2.467790e-03 0.5149425650 0.92990598 17 50993764 50993772 9 - 1.147 1.091 -0.202
ENSG00000008294 E036 44.6471572 1.364558e-03 0.8173494074 0.98217073 17 50993773 50993935 163 - 1.654 1.663 0.029
ENSG00000008294 E037 0.1283194 1.231448e-02 0.5638822942   17 50993936 50993937 2 - 0.094 0.000 -11.931
ENSG00000008294 E038 54.3657714 2.365184e-03 0.4971329959 0.92572055 17 50995057 50995224 168 - 1.757 1.725 -0.109
ENSG00000008294 E039 30.1568381 8.308460e-03 0.3607234467 0.89533854 17 50995444 50995533 90 - 1.466 1.521 0.191
ENSG00000008294 E040 1.4884224 2.261125e-02 0.6308417391   17 50995534 50995960 427 - 0.429 0.354 -0.424
ENSG00000008294 E041 2.2838411 1.649021e-02 0.0091023824   17 50996229 50996564 336 - 0.293 0.679 1.968
ENSG00000008294 E042 33.1748595 6.991988e-04 0.6579185946 0.95500146 17 50996565 50996694 130 - 1.523 1.544 0.072
ENSG00000008294 E043 0.2576729 1.615112e-02 0.2589513109   17 50998413 50998443 31 - 0.171 0.000 -12.862
ENSG00000008294 E044 43.3936059 3.423374e-04 0.5837191607 0.94207702 17 50998444 50998617 174 - 1.635 1.658 0.078
ENSG00000008294 E045 0.1283194 1.231448e-02 0.5638822942   17 50999476 50999487 12 - 0.094 0.000 -11.931
ENSG00000008294 E046 30.0186100 4.947786e-04 0.7375700817 0.96967057 17 50999661 50999717 57 - 1.500 1.480 -0.070
ENSG00000008294 E047 48.4959352 2.993892e-04 0.2950768490 0.87065294 17 51001715 51001834 120 - 1.715 1.668 -0.160
ENSG00000008294 E048 20.4254768 8.605521e-04 0.3924638538 0.90085552 17 51001835 51001836 2 - 1.356 1.298 -0.202
ENSG00000008294 E049 21.4997394 3.660329e-03 0.7808979855 0.97550172 17 51001837 51001845 9 - 1.361 1.340 -0.072
ENSG00000008294 E050 33.4162612 9.204049e-04 0.6592847860 0.95542166 17 51005212 51005263 52 - 1.526 1.547 0.072
ENSG00000008294 E051 57.1980375 3.158466e-04 0.4878079536 0.92316120 17 51006085 51006237 153 - 1.752 1.777 0.086
ENSG00000008294 E052 27.5417557 6.077173e-03 0.7382877191 0.96974549 17 51007269 51007326 58 - 1.466 1.442 -0.081
ENSG00000008294 E053 0.0000000       17 51007837 51007851 15 -      
ENSG00000008294 E054 0.0000000       17 51009131 51009142 12 -      
ENSG00000008294 E055 33.9677826 2.659890e-02 0.7645201995 0.97355432 17 51014232 51014353 122 - 1.556 1.528 -0.096
ENSG00000008294 E056 0.0000000       17 51014454 51014653 200 -      
ENSG00000008294 E057 0.0000000       17 51016226 51016256 31 -      
ENSG00000008294 E058 29.1999175 5.071916e-04 0.5793320642 0.94142672 17 51020159 51020258 100 - 1.466 1.494 0.098
ENSG00000008294 E059 0.1177530 1.169494e-02 0.5135788839   17 51020259 51020259 1 - 0.000 0.097 11.208
ENSG00000008294 E060 23.9446069 7.956761e-04 0.9191889649 0.99352169 17 51021158 51021251 94 - 1.400 1.392 -0.028
ENSG00000008294 E061 24.0423472 6.668479e-04 0.1662508614 0.78654357 17 51021252 51021365 114 - 1.436 1.350 -0.298
ENSG00000008294 E062 0.0000000       17 51030914 51031442 529 -      
ENSG00000008294 E063 0.3738645 1.682410e-02 0.6131455984   17 51031443 51031680 238 - 0.171 0.097 -0.939
ENSG00000008294 E064 4.0044865 3.456555e-02 0.0764373082 0.65893758 17 51031681 51031722 42 - 0.800 0.546 -1.076
ENSG00000008294 E065 0.0000000       17 51040428 51040451 24 -      
ENSG00000008294 E066 26.5004555 6.556756e-03 0.2633706491 0.85275672 17 51041501 51041651 151 - 1.473 1.396 -0.264
ENSG00000008294 E067 0.0000000       17 51046500 51046878 379 -      
ENSG00000008294 E068 20.9306775 8.347832e-04 0.3218948716 0.88089621 17 51047375 51047469 95 - 1.370 1.304 -0.230
ENSG00000008294 E069 0.1293601 1.237240e-02 0.5638921835   17 51047470 51047471 2 - 0.094 0.000 -11.931
ENSG00000008294 E070 0.0000000       17 51052748 51052801 54 -      
ENSG00000008294 E071 19.3082719 8.342240e-04 0.4137691196 0.90771193 17 51056412 51056482 71 - 1.332 1.276 -0.198
ENSG00000008294 E072 25.7309490 2.001390e-02 0.5870934918 0.94327995 17 51079584 51079704 121 - 1.447 1.401 -0.162
ENSG00000008294 E073 39.0422237 1.078273e-02 0.4522545073 0.91816398 17 51120354 51120868 515 - 1.581 1.623 0.143

Help

Please Click HERE to learn more details about the results from DEXseq.