ENSG00000027697

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000367739 ENSG00000027697 pgwt_inf pgKDN_inf IFNGR1 protein_coding protein_coding 677.7897 330.6231 599.0605 3.624478 2.15957 0.8574947 332.49448 260.70237 370.59500 8.440871 18.148737 0.5074233 0.57984167 0.788975 0.618525 -0.170450 2.178151e-03 8.794376e-06 FALSE TRUE
ENST00000458076 ENSG00000027697 pgwt_inf pgKDN_inf IFNGR1 protein_coding protein_coding 677.7897 330.6231 599.0605 3.624478 2.15957 0.8574947 69.68918 14.09518 40.36189 7.221640 4.959009 1.5171256 0.08326667 0.042250 0.067425 0.025175 8.869824e-01 8.794376e-06 FALSE TRUE
ENST00000696693 ENSG00000027697 pgwt_inf pgKDN_inf IFNGR1 protein_coding protein_coding 677.7897 330.6231 599.0605 3.624478 2.15957 0.8574947 239.67371 38.89662 159.32846 1.722872 13.809903 2.0340069 0.28509167 0.117700 0.266025 0.148325 8.794376e-06 8.794376e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000027697 E001 1.6506739 1.121282e-02 0.0719415995   6 137197483 137197484 2 - 0.497 0.210 -1.782
ENSG00000027697 E002 26.7013722 5.236901e-04 0.5509102616 0.93715547 6 137197485 137197496 12 - 1.439 1.403 -0.125
ENSG00000027697 E003 1357.2867449 2.186151e-04 0.1283487295 0.74218820 6 137197497 137198133 637 - 3.122 3.107 -0.048
ENSG00000027697 E004 1594.8390458 3.005309e-05 0.1157343361 0.72323000 6 137198134 137198639 506 - 3.191 3.179 -0.039
ENSG00000027697 E005 554.9295489 3.590102e-05 0.0361340854 0.54175580 6 137200881 137201008 128 - 2.738 2.710 -0.093
ENSG00000027697 E006 240.2444927 7.260159e-05 0.9768007740 0.99732900 6 137203499 137203532 34 - 2.366 2.365 -0.004
ENSG00000027697 E007 425.1489152 5.455418e-05 0.2495428526 0.84579545 6 137203533 137203642 110 - 2.607 2.623 0.055
ENSG00000027697 E008 278.5467400 9.072653e-05 0.2213022328 0.82773527 6 137203643 137203685 43 - 2.422 2.444 0.074
ENSG00000027697 E009 1.2221144 1.037837e-02 0.1742132783   6 137203686 137203730 45 - 0.250 0.458 1.262
ENSG00000027697 E010 587.3257928 4.199591e-05 0.5359078193 0.93401086 6 137204332 137204504 173 - 2.750 2.758 0.024
ENSG00000027697 E011 296.5697355 6.706390e-05 0.2284519362 0.83223650 6 137206136 137206206 71 - 2.449 2.470 0.070
ENSG00000027697 E012 272.3883084 8.794999e-05 0.3245894424 0.88279739 6 137206207 137206308 102 - 2.413 2.432 0.060
ENSG00000027697 E013 0.6093309 3.097862e-01 0.5117361387   6 137206642 137206962 321 - 0.143 0.286 1.263
ENSG00000027697 E014 284.9739166 5.870851e-04 0.3620295288 0.89533854 6 137206963 137207077 115 - 2.433 2.451 0.060
ENSG00000027697 E015 2.8823396 6.981987e-03 0.4311102457   6 137209850 137209972 123 - 0.615 0.502 -0.516
ENSG00000027697 E016 0.3748986 1.681474e-02 0.9341525337   6 137209973 137209984 12 - 0.143 0.118 -0.323
ENSG00000027697 E017 0.7174206 1.360337e-02 0.0255585891   6 137213751 137213832 82 - 0.077 0.408 2.999
ENSG00000027697 E018 12.1087892 8.875536e-03 0.0816635011 0.67077306 6 137215267 137215377 111 - 1.039 1.194 0.559
ENSG00000027697 E019 0.4931293 1.600289e-02 0.6412134198   6 137218028 137218060 33 - 0.143 0.210 0.677
ENSG00000027697 E020 3.8600158 3.791541e-03 0.9763630358 0.99732900 6 137218451 137218671 221 - 0.672 0.676 0.014
ENSG00000027697 E021 22.3283526 1.084568e-02 0.8389161186 0.98364976 6 137218672 137218983 312 - 1.358 1.340 -0.065
ENSG00000027697 E022 8.1308951 7.374945e-02 0.8113796361 0.98125070 6 137218984 137219093 110 - 0.963 0.912 -0.193
ENSG00000027697 E023 7.5884679 2.243844e-03 0.8876145957 0.99043423 6 137219094 137219242 149 - 0.914 0.928 0.053
ENSG00000027697 E024 207.0021193 8.100486e-05 0.0008224912 0.09746465 6 137219243 137219449 207 - 2.274 2.345 0.238

Help

Please Click HERE to learn more details about the results from DEXseq.