ENSG00000105643

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000222250 ENSG00000105643 pgwt_inf pgKDN_inf ARRDC2 protein_coding protein_coding 26.19059 22.65293 18.55661 1.733309 0.7418977 -0.2876241 5.839439 5.530141 1.9773726 1.3629065 0.7909682 -1.4790602 0.2028000 0.237275 0.102325 -0.134950 0.82937025 0.03660636 FALSE TRUE
ENST00000379656 ENSG00000105643 pgwt_inf pgKDN_inf ARRDC2 protein_coding protein_coding 26.19059 22.65293 18.55661 1.733309 0.7418977 -0.2876241 7.705317 10.094342 5.8275352 0.8785600 0.8584140 -0.7915441 0.3233250 0.463000 0.313525 -0.149475 0.88698240 0.03660636 FALSE TRUE
ENST00000595712 ENSG00000105643 pgwt_inf pgKDN_inf ARRDC2 protein_coding protein_coding 26.19059 22.65293 18.55661 1.733309 0.7418977 -0.2876241 5.209446 4.152778 3.2370897 1.0643853 2.1797071 -0.3583992 0.1937000 0.177925 0.183925 0.006000 0.88698240 0.03660636 FALSE TRUE
ENST00000600788 ENSG00000105643 pgwt_inf pgKDN_inf ARRDC2 protein_coding protein_coding_CDS_not_defined 26.19059 22.65293 18.55661 1.733309 0.7418977 -0.2876241 3.461380 1.694888 0.9763685 0.8272901 0.3453526 -0.7894782 0.1090417 0.067975 0.053675 -0.014300 1.00000000 0.03660636 TRUE FALSE
ENST00000683912 ENSG00000105643 pgwt_inf pgKDN_inf ARRDC2 protein_coding protein_coding 26.19059 22.65293 18.55661 1.733309 0.7418977 -0.2876241 2.608725 0.000000 5.4900385 0.0000000 2.1461199 9.1032979 0.1163417 0.000000 0.285700 0.285700 0.03660636 0.03660636 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000105643 E001 14.2365089 0.0143655746 0.2141432149 0.82285636 19 18001132 18001573 442 + 1.113 1.225 0.396
ENSG00000105643 E002 2.1842531 0.0156549127 0.5015823437   19 18007182 18007239 58 + 0.440 0.543 0.506
ENSG00000105643 E003 3.0616491 0.0325331955 0.8021774736   19 18007240 18007371 132 + 0.625 0.592 -0.146
ENSG00000105643 E004 2.1739671 0.0063426596 0.2364934459   19 18007590 18007740 151 + 0.391 0.568 0.884
ENSG00000105643 E005 1.9494169 0.1354811038 0.8644959985   19 18007741 18007842 102 + 0.440 0.488 0.243
ENSG00000105643 E006 0.8664868 0.0192036449 0.4056881841   19 18008168 18008169 2 + 0.336 0.210 -0.909
ENSG00000105643 E007 1.5843260 0.0265515738 0.8495494886   19 18008170 18008228 59 + 0.391 0.425 0.184
ENSG00000105643 E008 5.5487064 0.0058397412 0.0346690047 0.53757646 19 18008229 18008453 225 + 0.654 0.906 1.008
ENSG00000105643 E009 4.0938027 0.0035701201 0.0298862765 0.51330174 19 18008454 18008584 131 + 0.524 0.806 1.206
ENSG00000105643 E010 1.4358784 0.0105965218 0.0683977095   19 18008585 18008710 126 + 0.200 0.488 1.828
ENSG00000105643 E011 9.9695662 0.0014393571 0.1780238131 0.79548264 19 18008711 18008777 67 + 0.963 1.087 0.453
ENSG00000105643 E012 0.6093148 0.0210107096 0.9542480627   19 18008778 18008970 193 + 0.200 0.210 0.091
ENSG00000105643 E013 10.2297001 0.0024267414 0.2920909986 0.86950853 19 18008971 18009118 148 + 0.990 1.087 0.354
ENSG00000105643 E014 0.1176775 0.0116805124 0.7662654727   19 18009119 18009140 22 + 0.000 0.082 9.656
ENSG00000105643 E015 0.1177332 0.0116540499 0.7662947494   19 18009141 18009548 408 + 0.000 0.082 9.656
ENSG00000105643 E016 0.0000000       19 18009549 18009591 43 +      
ENSG00000105643 E017 0.0000000       19 18009592 18009694 103 +      
ENSG00000105643 E018 0.0000000       19 18009695 18009782 88 +      
ENSG00000105643 E019 12.1537801 0.0012102234 0.4003100568 0.90257726 19 18009783 18010039 257 + 1.151 1.087 -0.231
ENSG00000105643 E020 0.4931095 0.0161096964 0.7284451863   19 18010040 18010195 156 + 0.200 0.151 -0.494
ENSG00000105643 E021 19.2814211 0.0008462361 0.3119678553 0.87727291 19 18010196 18010358 163 + 1.338 1.275 -0.218
ENSG00000105643 E022 0.3642012 0.0169804763 0.8250838621   19 18010359 18010571 213 + 0.111 0.151 0.506
ENSG00000105643 E023 16.9808405 0.0065587920 0.0212687583 0.45299203 19 18010572 18010729 158 + 1.142 1.321 0.631
ENSG00000105643 E024 131.1298940 0.0001553480 0.0001377879 0.03094018 19 18012913 18014102 1190 + 2.153 2.088 -0.218

Help

Please Click HERE to learn more details about the results from DEXseq.