ENSG00000107581

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369144 ENSG00000107581 pgwt_inf pgKDN_inf EIF3A protein_coding protein_coding 76.20052 84.75577 86.15921 0.7159162 0.8179816 0.02369074 4.866442 3.658331 5.413094 0.4811539 0.1842533 0.5639922 0.06711667 0.043050 0.062825 0.019775 0.8869824 0.0465648 FALSE  
ENST00000541549 ENSG00000107581 pgwt_inf pgKDN_inf EIF3A protein_coding protein_coding 76.20052 84.75577 86.15921 0.7159162 0.8179816 0.02369074 38.417715 46.891493 42.667375 1.2986186 1.4126831 -0.1361624 0.49764167 0.553050 0.494925 -0.058125 0.8869824 0.0465648 FALSE  
MSTRG.4005.2 ENSG00000107581 pgwt_inf pgKDN_inf EIF3A protein_coding   76.20052 84.75577 86.15921 0.7159162 0.8179816 0.02369074 4.219856 1.045435 9.541837 1.0454354 1.3309485 3.1779399 0.05349167 0.012550 0.111125 0.098575 0.0465648 0.0465648 FALSE  
MSTRG.4005.3 ENSG00000107581 pgwt_inf pgKDN_inf EIF3A protein_coding   76.20052 84.75577 86.15921 0.7159162 0.8179816 0.02369074 28.629873 33.160506 28.438731 0.3579378 0.8877516 -0.2215367 0.38080833 0.391375 0.329975 -0.061400 0.8701092 0.0465648 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000107581 E001 14.5100508 0.0010536071 1.325478e-01 0.74845985 10 119033670 119034391 722 - 1.242 1.128 -0.405
ENSG00000107581 E002 108.4752019 0.0012512250 7.068706e-02 0.64492961 10 119034392 119035792 1401 - 2.066 2.009 -0.190
ENSG00000107581 E003 63.8569601 0.0004641500 2.034814e-01 0.81459608 10 119035793 119035983 191 - 1.834 1.786 -0.161
ENSG00000107581 E004 59.6861159 0.0002693487 6.519939e-01 0.95407392 10 119035984 119036030 47 - 1.791 1.774 -0.056
ENSG00000107581 E005 161.3279376 0.0001406550 6.568455e-01 0.95492248 10 119036031 119036268 238 - 2.205 2.216 0.038
ENSG00000107581 E006 156.4201885 0.0021215404 6.547814e-02 0.63240598 10 119037119 119037309 191 - 2.169 2.225 0.188
ENSG00000107581 E007 145.8429693 0.0001206723 8.262561e-01 0.98287690 10 119038238 119038439 202 - 2.164 2.170 0.021
ENSG00000107581 E008 113.6828903 0.0001408093 1.898101e-02 0.43856157 10 119041994 119042167 174 - 2.026 2.093 0.224
ENSG00000107581 E009 51.4196370 0.0002969452 4.363069e-05 0.01322628 10 119042168 119042220 53 - 1.627 1.800 0.587
ENSG00000107581 E010 39.7139073 0.0004273676 3.589424e-02 0.54049973 10 119042221 119042287 67 - 1.558 1.659 0.344
ENSG00000107581 E011 35.6890519 0.0004092511 7.074224e-01 0.96648985 10 119042288 119042310 23 - 1.555 1.574 0.067
ENSG00000107581 E012 215.3906800 0.0022625633 7.825531e-01 0.97619282 10 119042311 119042772 462 - 2.331 2.339 0.029
ENSG00000107581 E013 73.6658692 0.0028582368 9.263061e-01 0.99437046 10 119044054 119044142 89 - 1.875 1.871 -0.013
ENSG00000107581 E014 115.2131519 0.0001569673 5.424737e-01 0.93514816 10 119049801 119049985 185 - 2.056 2.074 0.060
ENSG00000107581 E015 81.9910926 0.0023414056 7.014763e-01 0.96500407 10 119050521 119050674 154 - 1.925 1.912 -0.046
ENSG00000107581 E016 0.8483056 0.0134256671 2.678797e-01   10 119050675 119050746 72 - 0.176 0.346 1.289
ENSG00000107581 E017 71.5945516 0.0005958313 5.079492e-02 0.59299322 10 119051199 119051321 123 - 1.893 1.823 -0.237
ENSG00000107581 E018 73.9219052 0.0014505466 3.603313e-01 0.89533854 10 119056740 119056853 114 - 1.891 1.857 -0.114
ENSG00000107581 E019 0.0000000       10 119056876 119056935 60 -      
ENSG00000107581 E020 72.2162188 0.0096758764 8.694661e-01 0.98753939 10 119056936 119057040 105 - 1.868 1.861 -0.023
ENSG00000107581 E021 140.9669584 0.0001083756 9.502363e-01 0.99613350 10 119057956 119058303 348 - 2.152 2.152 -0.002
ENSG00000107581 E022 77.3415005 0.0002117892 8.016450e-01 0.97976856 10 119059212 119059397 186 - 1.889 1.899 0.032
ENSG00000107581 E023 0.2470933 0.0162559432 9.847993e-01   10 119059398 119059601 204 - 0.097 0.095 -0.033
ENSG00000107581 E024 50.5038737 0.0022479234 3.219483e-01 0.88089621 10 119059602 119059718 117 - 1.733 1.688 -0.153
ENSG00000107581 E025 0.2587136 0.0164879165 2.341495e-01   10 119059719 119059890 172 - 0.176 0.000 -10.122
ENSG00000107581 E026 42.6602405 0.0082813074 5.525811e-01 0.93725877 10 119060746 119060844 99 - 1.622 1.659 0.126
ENSG00000107581 E027 41.5010044 0.0075486243 3.089300e-01 0.87553922 10 119061224 119061328 105 - 1.598 1.659 0.207
ENSG00000107581 E028 52.7969521 0.0003249947 5.241813e-01 0.93150282 10 119065399 119065570 172 - 1.743 1.717 -0.087
ENSG00000107581 E029 59.0961179 0.0069804843 2.408621e-01 0.83941200 10 119069446 119069654 209 - 1.749 1.808 0.202
ENSG00000107581 E030 56.3594245 0.0131676350 4.807902e-01 0.92248702 10 119070886 119071085 200 - 1.780 1.733 -0.160
ENSG00000107581 E031 45.1567526 0.0003134005 3.154474e-03 0.19865765 10 119072890 119073053 164 - 1.723 1.591 -0.448
ENSG00000107581 E032 38.1910622 0.0004697685 9.471503e-05 0.02358664 10 119073441 119073577 137 - 1.675 1.484 -0.653
ENSG00000107581 E033 40.5365585 0.0004690285 1.352170e-02 0.38839083 10 119073747 119073937 191 - 1.671 1.554 -0.396
ENSG00000107581 E034 23.0426906 0.0061374498 1.271869e-01 0.74121777 10 119080628 119080823 196 - 1.326 1.432 0.369

Help

Please Click HERE to learn more details about the results from DEXseq.