ENSG00000108179

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000225174 ENSG00000108179 pgwt_inf pgKDN_inf PPIF protein_coding protein_coding 198.6011 315.1254 243.6576 2.300481 2.620939 -0.3710573 173.509367 270.12376 221.465633 1.391009 1.281277 -0.2865260 0.85063333 0.85725 0.909075 0.051825 0.01047611 0.01047611 FALSE TRUE
ENST00000448165 ENSG00000108179 pgwt_inf pgKDN_inf PPIF protein_coding protein_coding 198.6011 315.1254 243.6576 2.300481 2.620939 -0.3710573 8.223202 13.43199 6.470969 2.047564 0.690667 -1.0524656 0.06570000 0.04275 0.026600 -0.016150 0.88698240 0.01047611 FALSE FALSE
ENST00000492149 ENSG00000108179 pgwt_inf pgKDN_inf PPIF protein_coding protein_coding_CDS_not_defined 198.6011 315.1254 243.6576 2.300481 2.620939 -0.3710573 13.957569 25.26203 13.295713 1.958667 2.241796 -0.9254957 0.07369167 0.08005 0.054325 -0.025725 0.83099515 0.01047611 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000108179 E001 58.074999 2.540396e-04 1.435323e-02 0.394654107 10 79347469 79347499 31 + 1.709 1.809 0.336
ENSG00000108179 E002 183.080251 9.702762e-05 9.760963e-02 0.699282991 10 79347500 79347657 158 + 2.240 2.278 0.125
ENSG00000108179 E003 144.052321 2.346201e-03 6.436898e-01 0.951115092 10 79347658 79347743 86 + 2.150 2.164 0.050
ENSG00000108179 E004 107.641265 1.457441e-04 6.708787e-02 0.637535732 10 79349076 79349106 31 + 2.001 2.055 0.182
ENSG00000108179 E005 168.248952 1.049937e-04 2.148078e-01 0.823220539 10 79349665 79349753 89 + 2.208 2.238 0.098
ENSG00000108179 E006 33.273684 4.215867e-03 1.119675e-02 0.361726641 10 79349754 79350035 282 + 1.440 1.591 0.517
ENSG00000108179 E007 239.435279 1.071046e-03 6.108398e-01 0.945973984 10 79351487 79351583 97 + 2.371 2.383 0.040
ENSG00000108179 E008 5.487471 1.168063e-01 8.040513e-01 0.979801524 10 79351584 79351714 131 + 0.776 0.834 0.228
ENSG00000108179 E009 208.873200 9.136326e-04 8.848931e-01 0.989847071 10 79352317 79352392 76 + 2.320 2.317 -0.011
ENSG00000108179 E010 13.646253 1.099376e-03 2.017487e-03 0.155843308 10 79353645 79353706 62 + 1.002 1.256 0.913
ENSG00000108179 E011 2077.739499 2.345985e-05 2.110775e-05 0.007678368 10 79353707 79355334 1628 + 3.324 3.307 -0.057

Help

Please Click HERE to learn more details about the results from DEXseq.