ENSG00000108654

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000540698 ENSG00000108654 pgwt_inf pgKDN_inf DDX5 protein_coding nonsense_mediated_decay 1070.166 1167.11 919.4191 141.7771 184.4637 -0.3441424 83.29164 97.80904 113.52953 6.395231 4.937133 0.2150074 0.09117500 0.090425 0.138575 0.048150 0.82937025 0.01432051 FALSE  
ENST00000581130 ENSG00000108654 pgwt_inf pgKDN_inf DDX5 protein_coding miRNA 1070.166 1167.11 919.4191 141.7771 184.4637 -0.3441424 638.32749 775.01403 404.96474 146.521413 159.879853 -0.9364091 0.50906667 0.642175 0.374725 -0.267450 0.88698240 0.01432051    
ENST00000581230 ENSG00000108654 pgwt_inf pgKDN_inf DDX5 protein_coding retained_intron 1070.166 1167.11 919.4191 141.7771 184.4637 -0.3441424 133.60402 126.58022 105.00337 1.744948 1.464369 -0.2695929 0.15334167 0.115150 0.131075 0.015925 0.93178586 0.01432051 TRUE  
ENST00000581693 ENSG00000108654 pgwt_inf pgKDN_inf DDX5 protein_coding nonsense_mediated_decay 1070.166 1167.11 919.4191 141.7771 184.4637 -0.3441424 76.13048 59.20142 106.33583 6.410674 4.843094 0.8448161 0.09026667 0.054275 0.136125 0.081850 0.16118874 0.01432051 FALSE  
ENST00000581806 ENSG00000108654 pgwt_inf pgKDN_inf DDX5 protein_coding protein_coding 1070.166 1167.11 919.4191 141.7771 184.4637 -0.3441424 32.51423 26.46435 69.75208 1.828448 5.106869 1.3978478 0.03830833 0.024575 0.087950 0.063375 0.01432051 0.01432051    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000108654 E001 0.2576795 1.617978e-02 2.348345e-01   17 64498254 64498256 3 - 0.176 0.000 -11.391
ENSG00000108654 E002 0.2576795 1.617978e-02 2.348345e-01   17 64498257 64498257 1 - 0.176 0.000 -13.978
ENSG00000108654 E003 0.2576795 1.617978e-02 2.348345e-01   17 64498258 64498258 1 - 0.176 0.000 -13.978
ENSG00000108654 E004 1.0095032 1.915263e-02 1.468924e-01   17 64498259 64498282 24 - 0.397 0.172 -1.617
ENSG00000108654 E005 57.5031477 2.588092e-04 7.956173e-02 6.649899e-01 17 64498283 64499615 1333 - 1.799 1.729 -0.237
ENSG00000108654 E006 24.3184578 6.874790e-04 3.345916e-01 8.874328e-01 17 64499616 64499635 20 - 1.374 1.432 0.202
ENSG00000108654 E007 76.1313035 1.281498e-03 4.180921e-01 9.097655e-01 17 64499636 64499694 59 - 1.901 1.871 -0.102
ENSG00000108654 E008 454.3655142 6.697364e-05 1.391591e-03 1.301334e-01 17 64499695 64499913 219 - 2.680 2.634 -0.152
ENSG00000108654 E009 666.6084590 3.266186e-05 2.669982e-02 4.936690e-01 17 64499914 64500133 220 - 2.836 2.811 -0.085
ENSG00000108654 E010 330.1707952 7.823964e-04 3.160774e-01 8.783967e-01 17 64500134 64500184 51 - 2.510 2.530 0.067
ENSG00000108654 E011 596.5403744 1.757107e-03 9.331322e-01 9.950620e-01 17 64500185 64500326 142 - 2.777 2.775 -0.008
ENSG00000108654 E012 83.5867144 5.362339e-04 5.211229e-01 9.308027e-01 17 64500327 64500548 222 - 1.916 1.938 0.075
ENSG00000108654 E013 666.9361762 5.521821e-05 2.653310e-03 1.810871e-01 17 64500549 64500773 225 - 2.841 2.806 -0.117
ENSG00000108654 E014 116.7609316 1.252252e-04 8.275833e-05 2.161682e-02 17 64500774 64500882 109 - 2.013 2.125 0.374
ENSG00000108654 E015 100.6752180 1.678233e-04 1.923459e-06 1.272175e-03 17 64500883 64500986 104 - 1.930 2.076 0.489
ENSG00000108654 E016 80.0611565 7.616060e-03 8.494860e-03 3.269024e-01 17 64500987 64501056 70 - 1.839 1.972 0.449
ENSG00000108654 E017 79.6211618 2.137306e-04 1.080411e-02 3.572921e-01 17 64501057 64501143 87 - 1.862 1.949 0.294
ENSG00000108654 E018 78.7808683 2.068699e-04 1.624139e-01 7.828791e-01 17 64501144 64501213 70 - 1.878 1.926 0.162
ENSG00000108654 E019 65.8441711 2.331956e-04 5.796518e-01 9.414544e-01 17 64501214 64501260 47 - 1.815 1.836 0.071
ENSG00000108654 E020 165.5256085 9.303043e-04 3.331888e-03 2.030219e-01 17 64501261 64501472 212 - 2.182 2.260 0.262
ENSG00000108654 E021 275.9582423 6.166156e-05 3.130408e-13 1.265276e-09 17 64501473 64501891 419 - 2.372 2.506 0.447
ENSG00000108654 E022 98.5482087 1.496588e-04 2.687056e-05 9.221419e-03 17 64501892 64502009 118 - 1.930 2.060 0.435
ENSG00000108654 E023 272.1937880 6.471339e-05 6.243770e-01 9.483597e-01 17 64502010 64502069 60 - 2.432 2.441 0.031
ENSG00000108654 E024 9.0354374 4.280442e-03 8.781114e-02 6.846288e-01 17 64502070 64502161 92 - 0.915 1.078 0.602
ENSG00000108654 E025 323.6339546 6.216446e-05 1.706986e-01 7.898367e-01 17 64502162 64502223 62 - 2.500 2.523 0.078
ENSG00000108654 E026 18.6003110 7.511364e-04 9.172195e-01 9.935217e-01 17 64502224 64502438 215 - 1.288 1.296 0.026
ENSG00000108654 E027 399.0126845 2.371917e-04 9.004355e-02 6.871159e-01 17 64502439 64502549 111 - 2.615 2.588 -0.091
ENSG00000108654 E028 1.9946414 4.425565e-02 3.368893e-01   17 64502550 64502584 35 - 0.543 0.391 -0.769
ENSG00000108654 E029 4.7880808 8.237295e-02 7.219522e-01 9.681439e-01 17 64502585 64502729 145 - 0.739 0.786 0.191
ENSG00000108654 E030 5.2275839 1.602964e-02 7.408568e-02 6.545762e-01 17 64502730 64502899 170 - 0.675 0.893 0.869
ENSG00000108654 E031 1.4681863 9.033171e-03 5.945537e-01   17 64502900 64502920 21 - 0.351 0.432 0.454
ENSG00000108654 E032 0.8563090 1.865098e-01 7.933098e-01   17 64502921 64502925 5 - 0.242 0.296 0.385
ENSG00000108654 E033 187.0746259 8.368208e-05 5.168531e-02 5.955237e-01 17 64502926 64502964 39 - 2.294 2.251 -0.144
ENSG00000108654 E034 347.5663991 5.649793e-05 1.017704e-01 7.060306e-01 17 64502965 64503094 130 - 2.555 2.528 -0.088
ENSG00000108654 E035 128.8327636 2.368020e-03 1.557386e-01 7.774373e-01 17 64503095 64503098 4 - 2.135 2.088 -0.156
ENSG00000108654 E036 2.0684241 6.545333e-03 2.460287e-01   17 64503099 64503187 89 - 0.397 0.566 0.843
ENSG00000108654 E037 284.6039986 6.408260e-05 2.197832e-01 8.258500e-01 17 64503188 64503298 111 - 2.466 2.444 -0.073
ENSG00000108654 E038 160.3440772 1.112134e-04 4.634448e-01 9.194424e-01 17 64503299 64503348 50 - 2.216 2.198 -0.058
ENSG00000108654 E039 2.4564906 5.781285e-03 6.954107e-01   17 64503349 64503429 81 - 0.511 0.566 0.258
ENSG00000108654 E040 308.2881773 1.168609e-04 6.380940e-02 6.278609e-01 17 64503430 64503567 138 - 2.505 2.473 -0.108
ENSG00000108654 E041 127.7046382 1.325159e-04 7.560731e-02 6.576551e-01 17 64503568 64503571 4 - 2.132 2.084 -0.160
ENSG00000108654 E042 1.8355130 7.980900e-03 4.696301e-01   17 64503572 64503802 231 - 0.397 0.504 0.553
ENSG00000108654 E043 180.6320819 2.405000e-04 2.379492e-01 8.367285e-01 17 64503803 64503838 36 - 2.272 2.245 -0.091
ENSG00000108654 E044 162.9980507 1.026916e-04 5.678011e-01 9.400357e-01 17 64503839 64503855 17 - 2.221 2.208 -0.045
ENSG00000108654 E045 139.0384859 1.385162e-04 6.751573e-01 9.585149e-01 17 64503856 64503868 13 - 2.141 2.152 0.037
ENSG00000108654 E046 0.7406672 1.467568e-02 9.776264e-01   17 64503869 64503982 114 - 0.242 0.238 -0.032
ENSG00000108654 E047 133.3551599 1.305306e-04 2.316943e-01 8.336640e-01 17 64503983 64503994 12 - 2.112 2.144 0.107
ENSG00000108654 E048 168.2921618 1.047242e-04 4.270617e-01 9.126395e-01 17 64503995 64504014 20 - 2.219 2.238 0.063
ENSG00000108654 E049 200.1809619 1.264036e-03 7.719628e-01 9.739526e-01 17 64504015 64504059 45 - 2.307 2.300 -0.025
ENSG00000108654 E050 227.9015969 2.163499e-04 2.096738e-01 8.196114e-01 17 64504060 64504116 57 - 2.372 2.346 -0.086
ENSG00000108654 E051 0.6229081 2.151474e-02 6.402666e-01   17 64504117 64504221 105 - 0.242 0.172 -0.617
ENSG00000108654 E052 237.1701669 7.530694e-05 4.309950e-01 9.146284e-01 17 64504222 64504272 51 - 2.384 2.369 -0.051
ENSG00000108654 E053 225.4887919 7.588985e-05 2.775707e-01 8.614677e-01 17 64504273 64504318 46 - 2.365 2.343 -0.073
ENSG00000108654 E054 1.3402994 1.193081e-02 3.902096e-01   17 64504319 64504676 358 - 0.300 0.432 0.776
ENSG00000108654 E055 442.7530721 4.928419e-05 8.218673e-01 9.824541e-01 17 64504677 64504842 166 - 2.645 2.649 0.012
ENSG00000108654 E056 0.2475644 1.671443e-02 9.858776e-01   17 64504843 64504880 38 - 0.097 0.095 -0.032
ENSG00000108654 E057 0.8578808 1.742018e-02 7.307179e-01   17 64504881 64505040 160 - 0.242 0.295 0.383
ENSG00000108654 E058 0.9725175 1.646778e-02 5.035493e-01   17 64505041 64505218 178 - 0.242 0.346 0.705
ENSG00000108654 E059 0.3648397 1.687728e-02 5.976800e-01   17 64505219 64505285 67 - 0.097 0.172 0.968
ENSG00000108654 E060 0.6124173 2.138735e-01 6.976294e-01   17 64505286 64505438 153 - 0.176 0.238 0.553
ENSG00000108654 E061 0.8462671 1.366270e-02 2.666479e-01   17 64505439 64505745 307 - 0.176 0.346 1.290
ENSG00000108654 E062 0.9651165 2.087378e-02 1.651003e-01   17 64505746 64506075 330 - 0.176 0.391 1.553
ENSG00000108654 E063 291.7697196 1.100685e-04 4.267232e-01 9.125408e-01 17 64506076 64506259 184 - 2.459 2.474 0.049
ENSG00000108654 E064 40.1902153 7.159325e-03 8.914762e-01 9.904342e-01 17 64506260 64506262 3 - 1.619 1.610 -0.032
ENSG00000108654 E065 38.5815821 5.132154e-03 9.163440e-01 9.934855e-01 17 64506263 64506513 251 - 1.600 1.594 -0.022
ENSG00000108654 E066 4.0425903 1.120516e-01 5.774683e-01 9.410657e-01 17 64506514 64506731 218 - 0.652 0.750 0.409
ENSG00000108654 E067 2.7242857 4.728329e-02 6.851441e-01   17 64506755 64506926 172 - 0.601 0.536 -0.295
ENSG00000108654 E068 0.1182043 1.169960e-02 5.503445e-01   17 64506927 64507314 388 - 0.000 0.095 12.272
ENSG00000108654 E069 0.0000000       17 64507315 64507477 163 -      
ENSG00000108654 E070 0.1182043 1.169960e-02 5.503445e-01   17 64507478 64507712 235 - 0.000 0.095 12.272
ENSG00000108654 E071 0.4824681 3.538344e-02 3.350523e-01   17 64508057 64508199 143 - 0.097 0.238 1.553

Help

Please Click HERE to learn more details about the results from DEXseq.