ENSG00000109332

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000321805 ENSG00000109332 pgwt_inf pgKDN_inf UBE2D3 protein_coding protein_coding 212.6361 222.64 233.8887 4.228439 6.386141 0.07110595 30.143929 34.59837 28.85949 2.604972 2.431406 -0.2615755 0.14237500 0.155050 0.123475 -0.031575 0.886982403 0.006189707 TRUE TRUE
ENST00000343106 ENSG00000109332 pgwt_inf pgKDN_inf UBE2D3 protein_coding protein_coding 212.6361 222.64 233.8887 4.228439 6.386141 0.07110595 19.239268 22.36845 16.74103 1.199755 1.265308 -0.4178602 0.09181667 0.100450 0.072150 -0.028300 0.833663018 0.006189707 FALSE TRUE
ENST00000394803 ENSG00000109332 pgwt_inf pgKDN_inf UBE2D3 protein_coding protein_coding 212.6361 222.64 233.8887 4.228439 6.386141 0.07110595 41.727808 25.12008 53.99330 8.799148 12.065577 1.1036324 0.20007500 0.114700 0.230750 0.116050 0.886982403 0.006189707 FALSE TRUE
ENST00000503418 ENSG00000109332 pgwt_inf pgKDN_inf UBE2D3 protein_coding nonsense_mediated_decay 212.6361 222.64 233.8887 4.228439 6.386141 0.07110595 6.204582 0.00000 16.33500 0.000000 5.596668 10.6746341 0.02751667 0.000000 0.069600 0.069600 0.006189707 0.006189707   FALSE
ENST00000510129 ENSG00000109332 pgwt_inf pgKDN_inf UBE2D3 protein_coding nonsense_mediated_decay 212.6361 222.64 233.8887 4.228439 6.386141 0.07110595 15.739005 24.15201 22.26805 5.464407 4.186422 -0.1171178 0.06973333 0.109475 0.095200 -0.014275 0.957334905 0.006189707   FALSE
MSTRG.22126.5 ENSG00000109332 pgwt_inf pgKDN_inf UBE2D3 protein_coding   212.6361 222.64 233.8887 4.228439 6.386141 0.07110595 51.930205 53.05069 61.15757 6.171213 14.873528 0.2051236 0.24256667 0.237550 0.261775 0.024225 0.998259694 0.006189707 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000109332 E001 0.0000000       4 102794383 102794385 3 -      
ENSG00000109332 E002 0.0000000       4 102794386 102794389 4 -      
ENSG00000109332 E003 0.5153591 4.607919e-02 4.735026e-02   4 102794390 102794494 105 - 0.299 0.000 -10.571
ENSG00000109332 E004 42.1788414 1.325894e-03 1.083439e-01 0.714223295 4 102794495 102795975 1481 - 1.670 1.593 -0.262
ENSG00000109332 E005 36.6560914 4.892665e-04 3.953978e-02 0.556848125 4 102795976 102796133 158 - 1.622 1.520 -0.349
ENSG00000109332 E006 610.5045607 3.861099e-05 4.733917e-06 0.002690714 4 102796134 102797150 1017 - 2.810 2.759 -0.172
ENSG00000109332 E007 149.3126357 1.080455e-04 2.119616e-02 0.452992029 4 102797151 102797234 84 - 2.203 2.147 -0.188
ENSG00000109332 E008 74.6335727 3.161561e-04 1.738549e-01 0.791633577 4 102797235 102797246 12 - 1.900 1.853 -0.159
ENSG00000109332 E009 69.8874045 1.135545e-03 3.920342e-01 0.900855517 4 102797247 102797251 5 - 1.865 1.833 -0.108
ENSG00000109332 E010 77.8104827 1.731188e-03 7.953468e-01 0.978938222 4 102797252 102797263 12 - 1.900 1.892 -0.030
ENSG00000109332 E011 147.5180281 6.510842e-04 5.227327e-01 0.931502823 4 102797264 102797321 58 - 2.179 2.163 -0.054
ENSG00000109332 E012 116.1894108 1.352116e-03 9.687879e-01 0.997256857 4 102797322 102797354 33 - 2.068 2.069 0.006
ENSG00000109332 E013 81.4087076 1.133818e-03 8.014985e-01 0.979768560 4 102797355 102797356 2 - 1.911 1.921 0.032
ENSG00000109332 E014 89.5896104 3.857284e-03 5.223186e-01 0.931502823 4 102797357 102797366 10 - 1.944 1.970 0.087
ENSG00000109332 E015 91.7043360 2.288824e-03 5.673110e-01 0.940035709 4 102797367 102797384 18 - 1.956 1.978 0.073
ENSG00000109332 E016 103.6203313 1.122731e-03 4.372324e-01 0.915999439 4 102797385 102797398 14 - 2.007 2.033 0.087
ENSG00000109332 E017 87.6453865 8.929246e-04 5.378749e-01 0.934421918 4 102797399 102797402 4 - 1.937 1.959 0.073
ENSG00000109332 E018 124.8450173 1.496837e-04 5.376722e-01 0.934421918 4 102797403 102797460 58 - 2.091 2.108 0.058
ENSG00000109332 E019 0.1293535 1.245854e-02 5.316947e-01   4 102798928 102798977 50 - 0.096 0.000 -11.236
ENSG00000109332 E020 127.4488344 1.316793e-04 6.063428e-01 0.945566377 4 102799407 102799466 60 - 2.101 2.116 0.048
ENSG00000109332 E021 97.5566219 1.607349e-04 6.207020e-01 0.948248731 4 102799467 102799500 34 - 2.000 1.986 -0.049
ENSG00000109332 E022 75.7114867 1.900632e-04 7.525239e-01 0.971227040 4 102801454 102801456 3 - 1.889 1.879 -0.035
ENSG00000109332 E023 85.6522743 1.743030e-04 9.808192e-01 0.997752981 4 102801457 102801468 12 - 1.937 1.938 0.005
ENSG00000109332 E024 74.8900698 2.079294e-04 7.408949e-01 0.969745490 4 102801469 102801472 4 - 1.874 1.886 0.041
ENSG00000109332 E025 93.7780058 2.106468e-04 8.792437e-01 0.989734090 4 102801473 102801508 36 - 1.974 1.979 0.018
ENSG00000109332 E026 74.0419636 3.308289e-04 8.967421e-01 0.990476239 4 102801509 102801522 14 - 1.872 1.878 0.018
ENSG00000109332 E027 96.6009288 1.673697e-04 8.574019e-01 0.985726275 4 102801523 102801559 37 - 1.986 1.992 0.021
ENSG00000109332 E028 5.7670024 7.820445e-02 6.778868e-01 0.959054114 4 102801560 102802348 789 - 0.793 0.867 0.291
ENSG00000109332 E029 0.4940686 1.341748e-01 9.807558e-01   4 102802349 102802369 21 - 0.175 0.173 -0.016
ENSG00000109332 E030 2.1013845 6.332823e-02 8.265339e-01   4 102802370 102802560 191 - 0.509 0.471 -0.186
ENSG00000109332 E031 120.0342417 1.248867e-04 1.587518e-01 0.777972350 4 102802561 102802611 51 - 2.063 2.103 0.132
ENSG00000109332 E032 111.5514863 1.335207e-04 3.810564e-02 0.549195285 4 102802612 102802638 27 - 2.021 2.081 0.201
ENSG00000109332 E033 0.2470867 1.658615e-02 9.917719e-01   4 102802639 102802694 56 - 0.096 0.095 -0.016
ENSG00000109332 E034 0.8583255 1.273099e-02 7.202018e-01   4 102809068 102809079 12 - 0.241 0.297 0.399
ENSG00000109332 E035 1.7500882 8.081447e-03 2.777160e-01   4 102809080 102809159 80 - 0.509 0.347 -0.864
ENSG00000109332 E036 0.3642767 1.679673e-02 5.912954e-01   4 102809160 102809184 25 - 0.096 0.173 0.984
ENSG00000109332 E037 1.4692635 8.722774e-03 5.825754e-01   4 102809430 102809671 242 - 0.350 0.434 0.470
ENSG00000109332 E038 131.8227535 3.420469e-04 2.671393e-02 0.493668987 4 102809672 102809703 32 - 2.093 2.153 0.202
ENSG00000109332 E039 0.2587136 1.622589e-02 2.381826e-01   4 102809704 102809723 20 - 0.175 0.000 -12.146
ENSG00000109332 E040 88.7071221 6.128357e-04 7.584469e-02 0.658267058 4 102809792 102809855 64 - 1.923 1.982 0.200
ENSG00000109332 E041 4.6210083 3.093180e-03 5.757456e-02 0.611322215 4 102809856 102810369 514 - 0.625 0.853 0.928
ENSG00000109332 E042 16.8127378 1.715559e-03 2.395828e-01 0.838914416 4 102810370 102812973 2604 - 1.207 1.293 0.301
ENSG00000109332 E043 0.8557629 1.715122e-02 7.192768e-01   4 102825239 102825317 79 - 0.241 0.297 0.399
ENSG00000109332 E044 1.4676661 8.881321e-03 5.817025e-01   4 102825318 102825477 160 - 0.350 0.434 0.470
ENSG00000109332 E045 1.2211294 1.034029e-02 5.431967e-01   4 102825478 102825721 244 - 0.299 0.393 0.569
ENSG00000109332 E046 0.6103293 2.208703e-02 6.671345e-01   4 102825722 102825737 16 - 0.175 0.239 0.569
ENSG00000109332 E047 0.4940814 9.450436e-02 9.834986e-01   4 102825738 102825860 123 - 0.175 0.173 -0.016
ENSG00000109332 E048 145.7135457 4.412315e-03 8.099069e-01 0.981100661 4 102826485 102826619 135 - 2.162 2.171 0.031
ENSG00000109332 E049 51.7474563 2.953395e-03 3.566114e-01 0.894485944 4 102826620 102826636 17 - 1.742 1.699 -0.147
ENSG00000109332 E050 40.5591406 4.617289e-03 3.520814e-02 0.539746526 4 102826637 102826767 131 - 1.558 1.675 0.397
ENSG00000109332 E051 22.7600377 3.693796e-03 3.565384e-02 0.539746526 4 102826768 102826844 77 - 1.303 1.442 0.486
ENSG00000109332 E052 28.9050156 5.128440e-04 3.346341e-04 0.058121880 4 102826845 102827152 308 - 1.367 1.568 0.692
ENSG00000109332 E053 7.1179654 4.748192e-03 4.730197e-01 0.920419159 4 102827153 102827426 274 - 0.872 0.946 0.284
ENSG00000109332 E054 46.1349342 1.205966e-02 6.166439e-01 0.947524853 4 102827427 102827591 165 - 1.659 1.688 0.100
ENSG00000109332 E055 4.1891673 3.225848e-02 9.526499e-01 0.996440343 4 102827592 102827599 8 - 0.717 0.713 -0.016
ENSG00000109332 E056 2.4303057 1.728019e-02 2.039183e-01   4 102827600 102827734 135 - 0.437 0.622 0.877
ENSG00000109332 E057 0.0000000       4 102827735 102827741 7 -      
ENSG00000109332 E058 0.0000000       4 102827742 102827943 202 -      
ENSG00000109332 E059 0.0000000       4 102827944 102828159 216 -      
ENSG00000109332 E060 0.3647708 1.674947e-02 5.916121e-01   4 102868715 102868896 182 - 0.096 0.173 0.984

Help

Please Click HERE to learn more details about the results from DEXseq.