ENSG00000115310

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000317610 ENSG00000115310 pgwt_inf pgKDN_inf RTN4 protein_coding protein_coding 352.3957 347.2042 399.4276 5.801011 2.053221 0.2021442 283.43591 322.88984 337.25523 4.530600 5.938153 0.06279686 0.795725 0.93015 0.844600 -0.085550 0.0002223579 0.0002223579 FALSE TRUE
ENST00000394609 ENSG00000115310 pgwt_inf pgKDN_inf RTN4 protein_coding protein_coding 352.3957 347.2042 399.4276 5.801011 2.053221 0.2021442 48.69412 8.80847 34.84301 3.696678 3.436118 1.98268292 0.147250 0.02495 0.087125 0.062175 0.4412294502 0.0002223579 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000115310 E001 0.1177530 1.166075e-02 5.312320e-01   2 54972187 54972188 2 - 0.000 0.096 9.878
ENSG00000115310 E002 848.6667206 3.175823e-05 2.515516e-04 0.048934191 2 54972189 54972584 396 - 2.946 2.909 -0.122
ENSG00000115310 E003 679.3965789 8.498144e-04 4.482983e-01 0.916954383 2 54972585 54972795 211 - 2.838 2.826 -0.040
ENSG00000115310 E004 123.1356265 9.188998e-04 6.557110e-01 0.954721932 2 54972796 54972796 1 - 2.100 2.086 -0.047
ENSG00000115310 E005 1038.1419180 2.484430e-04 2.278691e-01 0.831926629 2 54972797 54973198 402 - 3.022 3.009 -0.043
ENSG00000115310 E006 1.1985472 6.018056e-02 6.599150e-02   2 54973513 54973562 50 - 0.173 0.475 2.017
ENSG00000115310 E007 285.0117702 9.592492e-04 7.679828e-01 0.973554318 2 54973563 54973621 59 - 2.453 2.459 0.019
ENSG00000115310 E008 4.2146717 3.491860e-03 5.226378e-01 0.931502823 2 54973622 54973820 199 - 0.752 0.674 -0.324
ENSG00000115310 E009 282.4921171 3.012658e-04 5.644559e-01 0.939964167 2 54973821 54973867 47 - 2.447 2.457 0.035
ENSG00000115310 E010 6.5948514 2.206994e-03 1.472937e-01 0.768960751 2 54973868 54974191 324 - 0.946 0.793 -0.591
ENSG00000115310 E011 351.8586751 4.592503e-04 8.006349e-01 0.979508201 2 54974695 54974764 70 - 2.545 2.549 0.013
ENSG00000115310 E012 416.6126633 4.156234e-05 5.475633e-01 0.935820640 2 54982515 54982653 139 - 2.616 2.624 0.027
ENSG00000115310 E013 396.0528111 5.690653e-04 3.476907e-01 0.889822941 2 54987491 54987698 208 - 2.591 2.607 0.053
ENSG00000115310 E014 0.7512899 1.388944e-02 4.235579e-01   2 55010087 55010449 363 - 0.297 0.175 -0.983
ENSG00000115310 E015 11.9666524 2.176569e-02 8.600414e-01 0.986327645 2 55025086 55027206 2121 - 1.106 1.119 0.046
ENSG00000115310 E016 0.6011925 1.524056e-02 1.688722e-01   2 55027207 55027485 279 - 0.095 0.299 2.017
ENSG00000115310 E017 6.6764957 2.142304e-03 6.246214e-01 0.948359710 2 55028164 55028220 57 - 0.909 0.857 -0.197
ENSG00000115310 E018 0.2359573 1.571187e-02 2.379799e-01   2 55046816 55046886 71 - 0.000 0.175 12.615
ENSG00000115310 E019 0.1177530 1.166075e-02 5.312320e-01   2 55049079 55049198 120 - 0.000 0.096 11.739
ENSG00000115310 E020 0.6103092 2.051673e-02 6.472004e-01   2 55049558 55049744 187 - 0.173 0.241 0.602
ENSG00000115310 E021 901.4706869 3.629849e-05 1.917528e-05 0.007188729 2 55049745 55050427 683 - 2.935 2.975 0.133
ENSG00000115310 E022 66.9772910 2.200132e-04 9.512050e-01 0.996133504 2 55050428 55050598 171 - 1.833 1.830 -0.010
ENSG00000115310 E023 0.0000000       2 55050717 55050828 112 -      
ENSG00000115310 E024 0.1283194 1.231487e-02 5.453506e-01   2 55056483 55056557 75 - 0.095 0.000 -12.480
ENSG00000115310 E025 0.0000000       2 55060606 55060753 148 -      
ENSG00000115310 E026 0.0000000       2 55080489 55080639 151 -      
ENSG00000115310 E027 0.0000000       2 55112520 55112621 102 -      

Help

Please Click HERE to learn more details about the results from DEXseq.