ENSG00000118292

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000369099 ENSG00000118292 pgwt_inf pgKDN_inf C1orf54 protein_coding protein_coding 61.15873 58.71182 74.92788 2.71439 1.432387 0.3517984 9.803201 8.080889 9.336969 8.0808894 3.2668059 0.2082004 0.1666667 0.134175 0.122875 -0.0113 0.82937025 0.04966181 FALSE TRUE
MSTRG.1806.3 ENSG00000118292 pgwt_inf pgKDN_inf C1orf54 protein_coding   61.15873 58.71182 74.92788 2.71439 1.432387 0.3517984 32.577674 35.297910 40.259786 5.4343918 1.4145168 0.1897064 0.5312333 0.604500 0.537900 -0.0666 0.88698240 0.04966181 FALSE TRUE
MSTRG.1806.5 ENSG00000118292 pgwt_inf pgKDN_inf C1orf54 protein_coding   61.15873 58.71182 74.92788 2.71439 1.432387 0.3517984 4.285169 4.767900 2.637856 0.4000512 0.3654714 -0.8515522 0.0752000 0.080800 0.035200 -0.0456 0.72394074 0.04966181 FALSE TRUE
MSTRG.1806.6 ENSG00000118292 pgwt_inf pgKDN_inf C1orf54 protein_coding   61.15873 58.71182 74.92788 2.71439 1.432387 0.3517984 8.170658 3.892011 17.940363 3.8920109 2.4308379 2.2017233 0.1170833 0.061300 0.241000 0.1797 0.04966181 0.04966181 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000118292 E001 1.328659 0.0153688869 1.115313e-01   1 150268200 150268636 437 + 0.236 0.480 1.488
ENSG00000118292 E002 1.328659 0.0153688869 1.115313e-01   1 150268637 150268697 61 + 0.236 0.480 1.488
ENSG00000118292 E003 0.000000       1 150268698 150268698 1 +      
ENSG00000118292 E004 0.000000       1 150268699 150268820 122 +      
ENSG00000118292 E005 1.395439 0.0095185622 3.622519e-02   1 150272284 150272413 130 + 0.500 0.178 -2.097
ENSG00000118292 E006 1.213007 0.0119537354 1.799817e-01   1 150272729 150272741 13 + 0.236 0.442 1.295
ENSG00000118292 E007 5.059442 0.0029158561 9.994926e-01 0.999835708 1 150272742 150272779 38 + 0.781 0.782 0.002
ENSG00000118292 E008 4.832566 0.0029956674 5.199684e-01 0.930665096 1 150272780 150272789 10 + 0.798 0.724 -0.299
ENSG00000118292 E009 6.957140 0.0020513001 2.500264e-01 0.845931328 1 150272790 150272798 9 + 0.951 0.833 -0.448
ENSG00000118292 E010 33.354982 0.0004745542 9.776615e-02 0.699282991 1 150272799 150272863 65 + 1.571 1.489 -0.283
ENSG00000118292 E011 69.995137 0.0002528827 2.747501e-01 0.860034556 1 150274087 150274170 84 + 1.866 1.831 -0.121
ENSG00000118292 E012 67.164808 0.0004366459 4.479992e-01 0.916954383 1 150275741 150275799 59 + 1.820 1.846 0.089
ENSG00000118292 E013 76.972062 0.0002249541 4.914227e-01 0.924005274 1 150276522 150276632 111 + 1.901 1.879 -0.071
ENSG00000118292 E014 18.634667 0.0023829605 9.597935e-01 0.996748160 1 150279640 150279642 3 + 1.290 1.294 0.015
ENSG00000118292 E015 46.328345 0.0007834853 6.793595e-01 0.959434608 1 150279643 150279717 75 + 1.682 1.665 -0.058
ENSG00000118292 E016 21.432086 0.0035135270 5.426360e-01 0.935148162 1 150279718 150279741 24 + 1.331 1.371 0.139
ENSG00000118292 E017 20.675903 0.0007548290 1.125942e-05 0.005119799 1 150279742 150280834 1093 + 1.181 1.463 0.985
ENSG00000118292 E018 22.480869 0.0006527500 7.920940e-01 0.978472122 1 150280835 150281094 260 + 1.377 1.361 -0.054

Help

Please Click HERE to learn more details about the results from DEXseq.