ENSG00000128928

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000484250 ENSG00000128928 pgwt_inf pgKDN_inf IVD protein_coding retained_intron 29.60463 30.93933 26.35258 1.736906 0.7095001 -0.2314166 1.795424 2.126729 0.0000000 1.5413894 0.0000000 -7.7392601 0.05290000 0.061550 0.000000 -0.061550 0.82937025 0.02203699 FALSE TRUE
ENST00000487418 ENSG00000128928 pgwt_inf pgKDN_inf IVD protein_coding protein_coding 29.60463 30.93933 26.35258 1.736906 0.7095001 -0.2314166 13.497864 14.043972 19.0741511 0.4625826 0.3922055 0.4413971 0.47233333 0.459175 0.724450 0.265275 0.02203699 0.02203699 FALSE TRUE
ENST00000497816 ENSG00000128928 pgwt_inf pgKDN_inf IVD protein_coding retained_intron 29.60463 30.93933 26.35258 1.736906 0.7095001 -0.2314166 1.306372 1.722011 0.0000000 0.6789921 0.0000000 -7.4363041 0.04015833 0.052925 0.000000 -0.052925 0.09749437 0.02203699 FALSE TRUE
ENST00000559575 ENSG00000128928 pgwt_inf pgKDN_inf IVD protein_coding protein_coding 29.60463 30.93933 26.35258 1.736906 0.7095001 -0.2314166 3.058642 2.153037 0.1841739 0.7381350 0.1841739 -3.4776373 0.09592500 0.067350 0.007550 -0.059800 0.77361189 0.02203699   FALSE
ENST00000560660 ENSG00000128928 pgwt_inf pgKDN_inf IVD protein_coding retained_intron 29.60463 30.93933 26.35258 1.736906 0.7095001 -0.2314166 2.643418 3.287012 1.1988874 0.3877949 0.1493348 -1.4474792 0.08825833 0.108475 0.045325 -0.063150 0.82937025 0.02203699   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000128928 E001 0.2561313 0.0160223443 0.2703780386   15 40405485 40405794 310 + 0.168 0.000 -9.873
ENSG00000128928 E002 1.0079549 0.0116709709 0.1849246330   15 40405795 40405810 16 + 0.384 0.180 -1.468
ENSG00000128928 E003 14.8630742 0.0010193948 0.2131363555 0.8219789 15 40405811 40405971 161 + 1.154 1.247 0.332
ENSG00000128928 E004 0.7507763 0.0205075501 0.4733413887   15 40406074 40406181 108 + 0.289 0.180 -0.883
ENSG00000128928 E005 1.2120357 0.0101010588 0.1646956196   15 40406182 40406350 169 + 0.233 0.446 1.340
ENSG00000128928 E006 13.2874978 0.0112654456 0.4882619961 0.9231612 15 40407636 40407725 90 + 1.124 1.187 0.224
ENSG00000128928 E007 1.2232473 0.0103646326 0.4546104166   15 40407726 40407812 87 + 0.289 0.405 0.702
ENSG00000128928 E008 8.2180247 0.0283302620 0.3560652395 0.8944859 15 40407939 40407945 7 + 0.908 1.021 0.420
ENSG00000128928 E009 11.9289184 0.0016108303 0.3768388178 0.8986717 15 40407946 40407990 45 + 1.075 1.149 0.266
ENSG00000128928 E010 14.3175949 0.0010441656 0.9616434067 0.9967896 15 40410628 40410718 91 + 1.182 1.187 0.018
ENSG00000128928 E011 8.5070209 0.0016687642 0.8384556688 0.9835699 15 40410719 40410735 17 + 0.967 0.988 0.075
ENSG00000128928 E012 13.1208008 0.0011233047 0.5710528243 0.9402755 15 40410736 40410797 62 + 1.168 1.124 -0.156
ENSG00000128928 E013 18.8952992 0.0008329912 0.9353357824 0.9952219 15 40411260 40411353 94 + 1.299 1.295 -0.015
ENSG00000128928 E014 14.7988878 0.0010858183 0.8050455935 0.9800646 15 40411555 40411607 53 + 1.188 1.208 0.069
ENSG00000128928 E015 16.3395957 0.0009219014 0.4414739183 0.9168473 15 40411608 40411691 84 + 1.262 1.208 -0.190
ENSG00000128928 E016 0.0000000       15 40412612 40412679 68 +      
ENSG00000128928 E017 17.3561325 0.0008850540 0.4730065402 0.9204192 15 40412991 40413087 97 + 1.239 1.289 0.179
ENSG00000128928 E018 0.7183432 0.0421519471 0.0826338814   15 40413088 40413178 91 + 0.092 0.358 2.439
ENSG00000128928 E019 5.4332679 0.0025557101 0.0006266336 0.0822926 15 40414406 40414888 483 + 0.584 0.976 1.577
ENSG00000128928 E020 20.5634182 0.0007682930 0.3682108501 0.8976281 15 40414889 40414982 94 + 1.357 1.301 -0.197
ENSG00000128928 E021 1.5418402 0.0086819152 0.0006719713   15 40415146 40415400 255 + 0.092 0.610 3.702
ENSG00000128928 E022 18.3451122 0.0007922261 0.3127998689 0.8777085 15 40415401 40415482 82 + 1.315 1.247 -0.235
ENSG00000128928 E023 15.7590282 0.0151640843 0.6169817608 0.9478818 15 40416078 40416154 77 + 1.201 1.247 0.162
ENSG00000128928 E024 9.7347556 0.0307447322 0.8588792156 0.9863145 15 40416155 40416166 12 + 1.019 1.042 0.081
ENSG00000128928 E025 10.3259604 0.0226558840 0.4841510044 0.9229685 15 40416167 40416182 16 + 1.019 1.089 0.255
ENSG00000128928 E026 16.4912459 0.0011440994 0.4242044620 0.9120022 15 40416290 40416362 73 + 1.214 1.272 0.203
ENSG00000128928 E027 105.7987757 0.0005713559 0.0023317187 0.1669703 15 40418130 40419179 1050 + 2.063 1.980 -0.281
ENSG00000128928 E028 187.7182526 0.0058347388 0.9529330893 0.9964403 15 40419180 40421313 2134 + 2.274 2.274 -0.001
ENSG00000128928 E029 0.1278119 0.0122453691 0.5809736045   15 40424135 40424216 82 + 0.092 0.000 -11.379
ENSG00000128928 E030 0.8563128 0.0138633226 0.6335329590   15 40424217 40424473 257 + 0.233 0.307 0.532
ENSG00000128928 E031 0.3532392 0.0219638131 0.0900476113   15 40433854 40433914 61 + 0.000 0.248 12.297
ENSG00000128928 E032 9.1090006 0.0016267740 0.5724315832 0.9403605 15 40435417 40435947 531 + 0.978 1.031 0.195

Help

Please Click HERE to learn more details about the results from DEXseq.