ENSG00000130414

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000404554 ENSG00000130414 pgwt_inf pgKDN_inf NDUFA10 protein_coding protein_coding 48.21481 50.05024 50.92467 0.7239298 1.675507 0.02498278 5.453031 0.000000 11.795480 0.000000 5.2670928 10.2052410 0.11624167 0.000000 0.237175 0.237175 0.02536733 0.02536733 FALSE TRUE
ENST00000485344 ENSG00000130414 pgwt_inf pgKDN_inf NDUFA10 protein_coding retained_intron 48.21481 50.05024 50.92467 0.7239298 1.675507 0.02498278 5.251206 4.325219 3.851541 0.541177 0.3628186 -0.1669282 0.11221667 0.086075 0.075525 -0.010550 0.96041444 0.02536733 TRUE TRUE
ENST00000620965 ENSG00000130414 pgwt_inf pgKDN_inf NDUFA10 protein_coding protein_coding 48.21481 50.05024 50.92467 0.7239298 1.675507 0.02498278 20.084946 22.924339 20.823817 1.970550 4.3759428 -0.1385821 0.41430000 0.459200 0.405800 -0.053400 0.88698240 0.02536733 FALSE TRUE
ENST00000677567 ENSG00000130414 pgwt_inf pgKDN_inf NDUFA10 protein_coding protein_coding 48.21481 50.05024 50.92467 0.7239298 1.675507 0.02498278 2.622896 5.897231 0.000000 3.565831 0.0000000 -9.2063381 0.05322500 0.115475 0.000000 -0.115475 0.82937025 0.02536733 FALSE TRUE
ENST00000679158 ENSG00000130414 pgwt_inf pgKDN_inf NDUFA10 protein_coding protein_coding 48.21481 50.05024 50.92467 0.7239298 1.675507 0.02498278 8.952535 10.147255 9.281097 4.103353 3.2355561 -0.1285897 0.18194167 0.202250 0.179425 -0.022825 1.00000000 0.02536733 FALSE TRUE
ENST00000679308 ENSG00000130414 pgwt_inf pgKDN_inf NDUFA10 protein_coding nonsense_mediated_decay 48.21481 50.05024 50.92467 0.7239298 1.675507 0.02498278 1.648474 2.925523 0.000000 2.925523 0.0000000 -8.1974735 0.03479167 0.060400 0.000000 -0.060400 0.88698240 0.02536733 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000130414 E001 0.1177332 0.0116931440 0.5893176093   2 239892450 239892678 229 - 0.000 0.092 9.959
ENSG00000130414 E002 0.1177332 0.0116931440 0.5893176093   2 239892679 239892707 29 - 0.000 0.092 12.302
ENSG00000130414 E003 0.0000000       2 239895205 239895314 110 -      
ENSG00000130414 E004 0.2354305 0.0157318503 0.2753018467   2 239912249 239912434 186 - 0.000 0.168 13.254
ENSG00000130414 E005 0.1176775 0.0116642586 0.5893497082   2 239912801 239912990 190 - 0.000 0.092 12.302
ENSG00000130414 E006 0.0000000       2 239938374 239938710 337 -      
ENSG00000130414 E007 0.4940881 0.1013145070 0.9257975476   2 239949560 239951018 1459 - 0.181 0.168 -0.130
ENSG00000130414 E008 0.0000000       2 239957358 239957370 13 -      
ENSG00000130414 E009 0.0000000       2 239957371 239957371 1 -      
ENSG00000130414 E010 0.0000000       2 239957372 239957372 1 -      
ENSG00000130414 E011 0.0000000       2 239957373 239957373 1 -      
ENSG00000130414 E012 0.1283194 0.0123233012 0.4912742860   2 239957374 239957386 13 - 0.100 0.000 -12.917
ENSG00000130414 E013 0.1283194 0.0123233012 0.4912742860   2 239957387 239957390 4 - 0.100 0.000 -12.917
ENSG00000130414 E014 0.1283194 0.0123233012 0.4912742860   2 239957391 239957405 15 - 0.100 0.000 -12.917
ENSG00000130414 E015 0.1283194 0.0123233012 0.4912742860   2 239957406 239957408 3 - 0.100 0.000 -12.917
ENSG00000130414 E016 8.3956292 0.0029641491 0.4017620423 0.90273251 2 239957409 239958536 1128 - 1.012 0.931 -0.300
ENSG00000130414 E017 4.0489543 0.0039761376 0.7932874524 0.97871006 2 239958537 239959037 501 - 0.687 0.719 0.133
ENSG00000130414 E018 13.2799689 0.0011050190 0.9146939061 0.99327644 2 239959038 239960738 1701 - 1.151 1.159 0.030
ENSG00000130414 E019 0.7582851 0.2574061316 0.1681879947   2 239960739 239960739 1 - 0.359 0.092 -2.451
ENSG00000130414 E020 0.7582851 0.2574061316 0.1681879947   2 239960740 239960740 1 - 0.359 0.092 -2.451
ENSG00000130414 E021 7.4056181 0.0019896482 0.0003015390 0.05430240 2 239960741 239960781 41 - 1.073 0.699 -1.435
ENSG00000130414 E022 9.7613122 0.0022194215 0.0003911122 0.06410103 2 239960782 239960805 24 - 1.166 0.838 -1.215
ENSG00000130414 E023 11.9706445 0.0012400500 0.0020061759 0.15560482 2 239960806 239960832 27 - 1.223 0.966 -0.932
ENSG00000130414 E024 34.2626870 0.0005590046 0.4492015977 0.91727040 2 239960833 239960954 122 - 1.566 1.528 -0.131
ENSG00000130414 E025 32.5224690 0.0015057906 0.4300879061 0.91386524 2 239960955 239961022 68 - 1.504 1.546 0.143
ENSG00000130414 E026 53.8283839 0.0002957210 0.1537909385 0.77582207 2 239961023 239961163 141 - 1.710 1.767 0.193
ENSG00000130414 E027 26.2210545 0.0005701394 0.2079267433 0.81752196 2 239961164 239961186 23 - 1.397 1.470 0.249
ENSG00000130414 E028 0.4708214 0.0399804532 0.0589675894   2 239964183 239964261 79 - 0.000 0.288 14.138
ENSG00000130414 E029 0.9862393 0.0122396360 0.9002470222   2 239969221 239969762 542 - 0.308 0.288 -0.131
ENSG00000130414 E030 0.7512897 0.0143643916 0.3541271908   2 239972240 239972726 487 - 0.308 0.168 -1.131
ENSG00000130414 E031 2.9722386 0.0049083911 0.5326561503   2 239972727 239973661 935 - 0.639 0.555 -0.372
ENSG00000130414 E032 0.0000000       2 239976505 239976585 81 -      
ENSG00000130414 E033 0.0000000       2 239982115 239982219 105 -      
ENSG00000130414 E034 0.1177332 0.0116931440 0.5893176093   2 239983517 239983717 201 - 0.000 0.092 12.302
ENSG00000130414 E035 0.0000000       2 239987516 239987578 63 -      
ENSG00000130414 E036 0.0000000       2 239987915 239987929 15 -      
ENSG00000130414 E037 0.0000000       2 239987930 239987953 24 -      
ENSG00000130414 E038 0.0000000       2 239987954 239987961 8 -      
ENSG00000130414 E039 0.0000000       2 239987962 239987973 12 -      
ENSG00000130414 E040 0.9766184 0.0220000424 0.5688014875   2 239987974 239988445 472 - 0.249 0.338 0.606
ENSG00000130414 E041 0.1176775 0.0116642586 0.5893497082   2 239988446 239988448 3 - 0.000 0.092 12.302
ENSG00000130414 E042 0.3632424 0.0167391102 0.6414127410   2 239988449 239988612 164 - 0.100 0.168 0.869
ENSG00000130414 E043 0.7709762 0.0132218499 0.0069847557   2 239988613 239989251 639 - 0.406 0.000 -15.340
ENSG00000130414 E044 0.0000000       2 239989252 239989342 91 -      
ENSG00000130414 E045 0.1278119 0.0122336498 0.4913466848   2 239989343 239989896 554 - 0.100 0.000 -12.917
ENSG00000130414 E046 0.0000000       2 239989897 239990073 177 -      
ENSG00000130414 E047 53.6093211 0.0080963682 0.9165154463 0.99348548 2 239990074 239990182 109 - 1.733 1.741 0.028
ENSG00000130414 E048 1.3187315 0.0097130610 0.0426386553   2 239990183 239993569 3387 - 0.181 0.494 2.039
ENSG00000130414 E049 0.6325224 0.0142802927 0.1439132813   2 240000183 240000387 205 - 0.308 0.092 -2.131
ENSG00000130414 E050 50.6411339 0.0003733476 0.6402794689 0.95056070 2 240005210 240005286 77 - 1.703 1.723 0.066
ENSG00000130414 E051 24.8471112 0.0094537490 0.1568810763 0.77743733 2 240005287 240005295 9 - 1.360 1.459 0.343
ENSG00000130414 E052 35.4089555 0.0006180226 0.8603238121 0.98637920 2 240007316 240007370 55 - 1.557 1.566 0.030
ENSG00000130414 E053 40.1397827 0.0003797007 0.0955400462 0.69519050 2 240011617 240011696 80 - 1.651 1.574 -0.264
ENSG00000130414 E054 23.0454110 0.0006455088 0.0048038918 0.24378309 2 240011697 240012331 635 - 1.286 1.459 0.602
ENSG00000130414 E055 4.3940787 0.0037338010 0.2905650286 0.86872241 2 240012332 240012486 155 - 0.664 0.791 0.522
ENSG00000130414 E056 2.4459509 0.0076942423 0.4933498411   2 240012487 240012534 48 - 0.486 0.583 0.454
ENSG00000130414 E057 40.0664326 0.0003797453 0.1128315831 0.71758290 2 240012535 240014694 2160 - 1.575 1.649 0.251
ENSG00000130414 E058 2.7763542 0.1117951609 0.1048569873   2 240014695 240014738 44 - 0.406 0.699 1.373
ENSG00000130414 E059 27.6493569 0.0062317596 0.3377859670 0.88783772 2 240014739 240014768 30 - 1.486 1.426 -0.208
ENSG00000130414 E060 35.6450063 0.0004664792 0.6845200036 0.96037616 2 240014769 240014840 72 - 1.554 1.574 0.069
ENSG00000130414 E061 23.8640507 0.0008087924 0.0832395138 0.67453860 2 240014841 240014860 20 - 1.340 1.445 0.362
ENSG00000130414 E062 0.1278119 0.0122336498 0.4913466848   2 240017815 240017905 91 - 0.100 0.000 -12.917
ENSG00000130414 E063 0.2470376 0.0164996886 0.9437668227   2 240018407 240018523 117 - 0.100 0.092 -0.131
ENSG00000130414 E064 0.0000000       2 240018524 240018552 29 -      
ENSG00000130414 E065 17.8781081 0.0008221519 0.2021231763 0.81375236 2 240018553 240018554 2 - 1.230 1.318 0.308
ENSG00000130414 E066 32.1271845 0.0011112618 0.2191505635 0.82584996 2 240018555 240018639 85 - 1.486 1.552 0.224
ENSG00000130414 E067 0.1293601 0.0123861241 0.4912022071   2 240021087 240021116 30 - 0.100 0.000 -12.917
ENSG00000130414 E068 0.1177530 0.0117130927 0.5892412058   2 240021117 240021196 80 - 0.000 0.092 12.302
ENSG00000130414 E069 64.3524879 0.0002268671 0.4089657472 0.90644091 2 240021197 240021412 216 - 1.800 1.830 0.101
ENSG00000130414 E070 0.0000000       2 240021771 240021860 90 -      
ENSG00000130414 E071 48.6831510 0.0003252444 0.0321857083 0.52887183 2 240022172 240022340 169 - 1.739 1.649 -0.307
ENSG00000130414 E072 9.3159278 0.0015764665 0.0602342697 0.61949167 2 240025227 240025229 3 - 1.091 0.919 -0.636
ENSG00000130414 E073 14.8991115 0.0010598420 0.0208187730 0.44993643 2 240025230 240025247 18 - 1.280 1.106 -0.616
ENSG00000130414 E074 16.9887699 0.0010244525 0.0321548412 0.52879596 2 240025248 240025397 150 - 1.324 1.173 -0.533
ENSG00000130414 E075 0.0000000       2 240025572 240025743 172 -      

Help

Please Click HERE to learn more details about the results from DEXseq.