ENSG00000130511

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000270061 ENSG00000130511 pgwt_inf pgKDN_inf SSBP4 protein_coding protein_coding 141.6865 107.4864 129.6524 7.431362 20.44755 0.2704718 20.790759 16.507663 24.523242 9.538308 3.382211 0.5707284 0.16472500 0.164875 0.210900 0.046025 0.88698240 0.02917645 FALSE TRUE
ENST00000348495 ENSG00000130511 pgwt_inf pgKDN_inf SSBP4 protein_coding protein_coding 141.6865 107.4864 129.6524 7.431362 20.44755 0.2704718 19.335904 16.584140 28.892606 8.650748 4.873630 0.8005257 0.14482500 0.148075 0.223050 0.074975 0.88698240 0.02917645 FALSE TRUE
ENST00000601444 ENSG00000130511 pgwt_inf pgKDN_inf SSBP4 protein_coding retained_intron 141.6865 107.4864 129.6524 7.431362 20.44755 0.2704718 14.111680 7.901403 2.183463 4.562773 1.307810 -1.8507230 0.08512500 0.070525 0.017525 -0.053000 0.99604486 0.02917645 FALSE FALSE
ENST00000625926 ENSG00000130511 pgwt_inf pgKDN_inf SSBP4 protein_coding protein_coding 141.6865 107.4864 129.6524 7.431362 20.44755 0.2704718 22.461418 10.829384 25.225080 6.270792 17.839133 1.2191479 0.13465833 0.091900 0.149050 0.057150 1.00000000 0.02917645   FALSE
MSTRG.14791.4 ENSG00000130511 pgwt_inf pgKDN_inf SSBP4 protein_coding   141.6865 107.4864 129.6524 7.431362 20.44755 0.2704718 8.365163 14.905420 0.000000 7.620636 0.000000 -10.5425889 0.06982500 0.145975 0.000000 -0.145975 0.02917645 0.02917645 FALSE TRUE
MSTRG.14791.6 ENSG00000130511 pgwt_inf pgKDN_inf SSBP4 protein_coding   141.6865 107.4864 129.6524 7.431362 20.44755 0.2704718 13.158701 11.233004 18.073482 7.042438 1.376123 0.6856450 0.09912500 0.096775 0.149525 0.052750 0.88698240 0.02917645 FALSE TRUE
MSTRG.14791.7 ENSG00000130511 pgwt_inf pgKDN_inf SSBP4 protein_coding   141.6865 107.4864 129.6524 7.431362 20.44755 0.2704718 1.845000 5.534999 0.000000 5.534999 0.000000 -9.1150434 0.01827500 0.054825 0.000000 -0.054825 0.88698240 0.02917645 FALSE TRUE
MSTRG.14791.8 ENSG00000130511 pgwt_inf pgKDN_inf SSBP4 protein_coding   141.6865 107.4864 129.6524 7.431362 20.44755 0.2704718 10.293152 5.696702 8.742249 3.473752 5.058913 0.6169966 0.08061667 0.058050 0.089825 0.031775 1.00000000 0.02917645 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000130511 E001 0.9867334 0.0136141277 9.888753e-01   19 18418864 18419149 286 + 0.299 0.297 -0.010
ENSG00000130511 E002 0.5058201 0.0282844482 3.171630e-01   19 18419214 18419335 122 + 0.241 0.095 -1.595
ENSG00000130511 E003 4.7625350 0.0078372834 1.729826e-01 0.791093964 19 18419336 18419397 62 + 0.673 0.838 0.668
ENSG00000130511 E004 8.2659246 0.0025138120 8.666276e-01 0.987140316 19 18419398 18419425 28 + 0.973 0.959 -0.053
ENSG00000130511 E005 8.9827262 0.0016409479 7.672227e-01 0.973554318 19 18419426 18419429 4 + 0.985 1.014 0.108
ENSG00000130511 E006 50.8421695 0.0002870197 6.070174e-01 0.945666651 19 18419430 18419605 176 + 1.703 1.727 0.081
ENSG00000130511 E007 25.2723436 0.0018765254 8.750157e-01 0.988633358 19 18419606 18419615 10 + 1.423 1.416 -0.024
ENSG00000130511 E008 25.1785393 0.0009866462 6.156595e-01 0.947290697 19 18419616 18419623 8 + 1.431 1.403 -0.095
ENSG00000130511 E009 34.1224724 0.0006176019 2.396524e-01 0.839054652 19 18419624 18419648 25 + 1.572 1.514 -0.199
ENSG00000130511 E010 52.6839344 0.0012402835 6.531317e-01 0.954074225 19 18419649 18419707 59 + 1.738 1.720 -0.058
ENSG00000130511 E011 0.6219362 0.0148196087 6.467239e-01   19 18420103 18420124 22 + 0.241 0.173 -0.595
ENSG00000130511 E012 9.7109411 0.0014931405 2.101408e-03 0.158852965 19 18422470 18423294 825 + 0.871 1.154 1.044
ENSG00000130511 E013 1.9613783 0.1264121053 7.455190e-01   19 18425909 18426039 131 + 0.436 0.506 0.353
ENSG00000130511 E014 0.6098218 0.0149132547 6.669727e-01   19 18426040 18426083 44 + 0.174 0.240 0.575
ENSG00000130511 E015 4.1260967 0.0065696639 4.667633e-02 0.581830028 19 18427078 18427350 273 + 0.570 0.822 1.054
ENSG00000130511 E016 63.1005535 0.0003379929 3.719170e-01 0.898011355 19 18427351 18427423 73 + 1.821 1.790 -0.106
ENSG00000130511 E017 54.0868303 0.0085216779 4.914939e-01 0.924005274 19 18427752 18427813 62 + 1.757 1.723 -0.116
ENSG00000130511 E018 64.8738546 0.0002399722 7.507512e-01 0.970576273 19 18427898 18427982 85 + 1.823 1.813 -0.032
ENSG00000130511 E019 66.1447423 0.0071042663 7.483790e-01 0.970346664 19 18430841 18430930 90 + 1.820 1.834 0.049
ENSG00000130511 E020 27.1203322 0.0005192804 9.266187e-01 0.994468077 19 18431353 18431418 66 + 1.450 1.447 -0.010
ENSG00000130511 E021 0.4718192 0.0159269084 4.662146e-02   19 18431645 18431646 2 + 0.000 0.297 12.241
ENSG00000130511 E022 40.7073407 0.0045714610 5.366051e-01 0.934288177 19 18431647 18431671 25 + 1.603 1.638 0.121
ENSG00000130511 E023 46.5903992 0.0003241054 9.035361e-01 0.991432816 19 18431672 18431706 35 + 1.679 1.676 -0.010
ENSG00000130511 E024 0.4708412 0.0160803024 4.654205e-02   19 18431707 18431792 86 + 0.000 0.297 12.241
ENSG00000130511 E025 41.3576368 0.0003502584 5.883735e-01 0.943560448 19 18431793 18431812 20 + 1.613 1.641 0.093
ENSG00000130511 E026 55.4933671 0.0003488061 3.415142e-01 0.889241634 19 18431813 18431862 50 + 1.732 1.772 0.137
ENSG00000130511 E027 63.2164981 0.0032717653 8.335186e-01 0.983026071 19 18432000 18432066 67 + 1.801 1.813 0.040
ENSG00000130511 E028 38.2013268 0.0004182315 9.077807e-01 0.992175852 19 18432067 18432070 4 + 1.589 1.597 0.027
ENSG00000130511 E029 60.5389920 0.0003099447 9.241798e-01 0.994243392 19 18432147 18432199 53 + 1.789 1.788 -0.004
ENSG00000130511 E030 38.7622503 0.0013862629 5.841589e-01 0.942136691 19 18432200 18432214 15 + 1.611 1.586 -0.084
ENSG00000130511 E031 54.7280878 0.0053651759 3.833104e-01 0.900350395 19 18432559 18432604 46 + 1.764 1.725 -0.134
ENSG00000130511 E032 1.2331878 0.0108436795 9.830273e-01   19 18432605 18432699 95 + 0.349 0.348 -0.010
ENSG00000130511 E033 54.4194573 0.0033022349 1.710702e-01 0.790011451 19 18432700 18432735 36 + 1.772 1.710 -0.207
ENSG00000130511 E034 69.3093552 0.0017046930 2.685398e-01 0.857675589 19 18432829 18432883 55 + 1.866 1.825 -0.139
ENSG00000130511 E035 75.9361056 0.0017529223 9.489561e-01 0.996133504 19 18432973 18433043 71 + 1.886 1.886 -0.001
ENSG00000130511 E036 2.2387016 0.1108617455 4.292531e-01   19 18433044 18433100 57 + 0.570 0.434 -0.662
ENSG00000130511 E037 64.5482100 0.0002364215 4.733648e-01 0.920419159 19 18433135 18433213 79 + 1.828 1.803 -0.082
ENSG00000130511 E038 4.2851446 0.0562102981 5.217001e-01 0.931036596 19 18433275 18433584 310 + 0.673 0.771 0.405
ENSG00000130511 E039 48.1085180 0.0003158414 1.348723e-01 0.750535558 19 18433585 18433613 29 + 1.719 1.657 -0.211
ENSG00000130511 E040 0.9999082 0.0136397112 4.724885e-01   19 18433614 18433652 39 + 0.349 0.240 -0.747
ENSG00000130511 E041 70.1400401 0.0002218443 3.144248e-03 0.198573446 19 18433710 18433817 108 + 1.898 1.795 -0.348
ENSG00000130511 E042 41.1193432 0.0049561767 1.477091e-01 0.769197379 19 18433818 18433932 115 + 1.583 1.664 0.275
ENSG00000130511 E043 54.0832148 0.0052181321 4.894149e-06 0.002738991 19 18433933 18434216 284 + 1.613 1.846 0.789
ENSG00000130511 E044 71.8354267 0.0033133303 3.163511e-01 0.878396699 19 18434217 18434562 346 + 1.840 1.884 0.148

Help

Please Click HERE to learn more details about the results from DEXseq.