ENSG00000131467

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000590720 ENSG00000131467 pgwt_inf pgKDN_inf PSME3 protein_coding protein_coding 53.45973 60.73626 58.97639 1.327458 1.255244 -0.0424133 49.21504 52.60028 57.75206 1.125851 1.426166 0.1347776 0.9210667 0.86715 0.979325 0.112175 0.00374466 0.00374466 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000131467 E001 0.0000000       17 42824385 42824414 30 +      
ENSG00000131467 E002 0.1278119 1.226960e-02 0.4992747233   17 42824426 42824870 445 + 0.099 0.000 -11.212
ENSG00000131467 E003 0.0000000       17 42825758 42825858 101 +      
ENSG00000131467 E004 0.0000000       17 42826971 42827081 111 +      
ENSG00000131467 E005 0.0000000       17 42827198 42827349 152 +      
ENSG00000131467 E006 0.0000000       17 42833015 42833026 12 +      
ENSG00000131467 E007 0.1177530 1.165797e-02 0.5799958246   17 42833142 42833396 255 + 0.000 0.093 12.322
ENSG00000131467 E008 0.1177530 1.165797e-02 0.5799958246   17 42833397 42833398 2 + 0.000 0.093 12.322
ENSG00000131467 E009 0.2354305 1.571321e-02 0.2693218993   17 42833399 42833410 12 + 0.000 0.169 13.266
ENSG00000131467 E010 1.1988876 1.863123e-01 0.1316480152   17 42833411 42833417 7 + 0.179 0.462 1.896
ENSG00000131467 E011 1.3165650 2.329279e-01 0.1114784875   17 42833418 42833418 1 + 0.179 0.497 2.066
ENSG00000131467 E012 7.1172060 2.250445e-03 0.6211209786 0.94827372 17 42833419 42833436 18 + 0.883 0.935 0.195
ENSG00000131467 E013 11.4439309 1.248225e-03 0.9593470975 0.99674388 17 42833437 42833444 8 + 1.097 1.094 -0.011
ENSG00000131467 E014 15.4076677 9.794216e-04 0.6134160316 0.94662817 17 42833445 42833470 26 + 1.233 1.197 -0.127
ENSG00000131467 E015 21.2394069 6.856447e-04 0.5198201123 0.93066510 17 42833471 42833495 25 + 1.326 1.368 0.146
ENSG00000131467 E016 24.4653578 6.212441e-04 0.8033525810 0.97976856 17 42833496 42833505 10 + 1.398 1.414 0.055
ENSG00000131467 E017 31.7743625 5.000957e-04 0.2835732973 0.86518039 17 42833506 42833548 43 + 1.486 1.544 0.198
ENSG00000131467 E018 55.3484810 2.905189e-04 0.0198162730 0.44469868 17 42833549 42833673 125 + 1.701 1.796 0.320
ENSG00000131467 E019 0.1293601 1.248077e-02 0.4990794352   17 42833674 42833775 102 + 0.099 0.000 -13.149
ENSG00000131467 E020 0.3648463 1.681006e-02 0.6317924780   17 42833776 42833939 164 + 0.099 0.169 0.896
ENSG00000131467 E021 0.1182043 1.173100e-02 0.5799517703   17 42833940 42834093 154 + 0.000 0.093 12.321
ENSG00000131467 E022 0.7069099 2.316405e-02 0.0126808529   17 42834094 42834256 163 + 0.000 0.385 14.735
ENSG00000131467 E023 0.6219560 1.445823e-02 0.5972473930   17 42834257 42834343 87 + 0.247 0.169 -0.689
ENSG00000131467 E024 33.3214816 4.399863e-04 0.0915172778 0.68836594 17 42834344 42834376 33 + 1.490 1.578 0.301
ENSG00000131467 E025 35.0922805 1.871844e-03 0.2312693485 0.83366405 17 42834515 42834541 27 + 1.524 1.589 0.220
ENSG00000131467 E026 32.6773156 5.152138e-04 0.4634740023 0.91944240 17 42834542 42834577 36 + 1.507 1.547 0.135
ENSG00000131467 E027 54.6805606 2.876007e-04 0.6760162788 0.95899248 17 42834772 42834876 105 + 1.753 1.738 -0.052
ENSG00000131467 E028 35.9839129 3.974449e-04 0.5977538479 0.94401404 17 42837649 42837697 49 + 1.580 1.555 -0.085
ENSG00000131467 E029 0.2460526 1.656757e-02 0.9535400830   17 42837698 42837755 58 + 0.099 0.093 -0.104
ENSG00000131467 E030 55.1708436 4.898251e-04 0.6769292736 0.95903697 17 42838093 42838205 113 + 1.757 1.742 -0.053
ENSG00000131467 E031 0.3536707 3.402763e-02 0.1211116295   17 42838692 42838730 39 + 0.000 0.234 13.696
ENSG00000131467 E032 42.8716971 2.696900e-03 0.4897696774 0.92321150 17 42838731 42838799 69 + 1.624 1.660 0.119
ENSG00000131467 E033 45.9393003 3.381665e-04 0.0335348004 0.53428436 17 42838945 42839012 68 + 1.622 1.717 0.322
ENSG00000131467 E034 0.8467376 1.268608e-02 0.2963707483   17 42839013 42839111 99 + 0.179 0.340 1.218
ENSG00000131467 E035 42.7559064 2.223514e-03 0.4627853063 0.91941919 17 42839112 42839166 55 + 1.622 1.660 0.128
ENSG00000131467 E036 53.0462347 2.936472e-04 0.2804943595 0.86331697 17 42839294 42839380 87 + 1.753 1.711 -0.145
ENSG00000131467 E037 620.4784437 4.412391e-05 0.0002789385 0.05177012 17 42841498 42843760 2263 + 2.808 2.778 -0.101

Help

Please Click HERE to learn more details about the results from DEXseq.