ENSG00000134516

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000520450 ENSG00000134516 pgwt_inf pgKDN_inf DOCK2 protein_coding retained_intron 42.83887 47.22008 48.57949 0.5559497 0.1643529 0.04093822 2.362972 2.167546 1.629655 0.313585 0.2490087 -0.4093108 0.06021667 0.046050 0.033525 -0.012525 0.88830176 0.03945911 FALSE TRUE
ENST00000520908 ENSG00000134516 pgwt_inf pgKDN_inf DOCK2 protein_coding protein_coding 42.83887 47.22008 48.57949 0.5559497 0.1643529 0.04093822 13.294618 18.689061 16.319739 1.477272 3.7019629 -0.1954641 0.29245833 0.394850 0.335825 -0.059025 0.88698240 0.03945911 FALSE TRUE
ENST00000523351 ENSG00000134516 pgwt_inf pgKDN_inf DOCK2 protein_coding protein_coding_CDS_not_defined 42.83887 47.22008 48.57949 0.5559497 0.1643529 0.04093822 13.624667 18.391395 9.177445 1.317507 4.1703905 -1.0020796 0.32732500 0.389250 0.188800 -0.200450 0.82937025 0.03945911 FALSE TRUE
MSTRG.23895.7 ENSG00000134516 pgwt_inf pgKDN_inf DOCK2 protein_coding   42.83887 47.22008 48.57949 0.5559497 0.1643529 0.04093822 4.159941 0.000000 8.163648 0.000000 3.7735719 9.6748363 0.10017500 0.000000 0.168175 0.168175 0.03945911 0.03945911 FALSE TRUE
MSTRG.23895.8 ENSG00000134516 pgwt_inf pgKDN_inf DOCK2 protein_coding   42.83887 47.22008 48.57949 0.5559497 0.1643529 0.04093822 5.345157 3.202320 9.643374 1.848905 4.3811592 1.5874175 0.12295833 0.068525 0.198575 0.130050 0.88698240 0.03945911 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000134516 E001 0.4931034 0.0159984024 0.9805624113   5 169637238 169637267 30 + 0.175 0.173 -0.026
ENSG00000134516 E002 0.6108564 0.0195307080 0.6776636378   5 169637268 169637274 7 + 0.175 0.239 0.559
ENSG00000134516 E003 1.1030012 0.3859892150 0.9018646136   5 169637275 169637285 11 + 0.300 0.346 0.296
ENSG00000134516 E004 1.6915954 0.2822056194 0.3036079156   5 169637286 169637290 5 + 0.300 0.537 1.296
ENSG00000134516 E005 3.6463442 0.0879909744 0.1820885754   5 169637291 169637326 36 + 0.542 0.770 0.974
ENSG00000134516 E006 5.2419013 0.0452015373 0.1878708874 0.80534755 5 169637327 169637369 43 + 0.697 0.880 0.729
ENSG00000134516 E007 9.3464380 0.0350830681 0.6299311860 0.94854734 5 169654403 169654486 84 + 0.987 1.042 0.202
ENSG00000134516 E008 0.0000000       5 169654487 169654806 320 +      
ENSG00000134516 E009 8.3444540 0.0087260268 0.4168053088 0.90965803 5 169669288 169669328 41 + 0.927 1.012 0.315
ENSG00000134516 E010 0.0000000       5 169670167 169670189 23 +      
ENSG00000134516 E011 11.8014725 0.0050368893 0.6403097714 0.95056070 5 169670542 169670597 56 + 1.086 1.129 0.155
ENSG00000134516 E012 18.1584191 0.0007547066 0.4715834894 0.92009850 5 169671078 169671174 97 + 1.304 1.257 -0.163
ENSG00000134516 E013 25.9706563 0.0042531789 0.2924016498 0.86980441 5 169674297 169674445 149 + 1.460 1.397 -0.218
ENSG00000134516 E014 0.1182043 0.0117263498 0.5514845946   5 169681730 169681743 14 + 0.000 0.095 10.251
ENSG00000134516 E015 23.7982877 0.0010242250 0.8104223263 0.98124960 5 169681744 169681879 136 + 1.400 1.388 -0.041
ENSG00000134516 E016 24.0174475 0.0021451480 0.9679189607 0.99719584 5 169684196 169684350 155 + 1.395 1.401 0.019
ENSG00000134516 E017 9.0252745 0.0335006046 0.5790852392 0.94142672 5 169689252 169689275 24 + 1.029 0.969 -0.223
ENSG00000134516 E018 12.3555871 0.0011576395 0.4741274296 0.92065707 5 169689276 169689333 58 + 1.151 1.096 -0.199
ENSG00000134516 E019 0.0000000       5 169695179 169695216 38 +      
ENSG00000134516 E020 0.1278119 0.0122686728 0.5252876172   5 169695286 169695364 79 + 0.096 0.000 -11.104
ENSG00000134516 E021 13.6934851 0.0107257091 0.7169238760 0.96779455 5 169695803 169695848 46 + 1.181 1.152 -0.104
ENSG00000134516 E022 19.3681259 0.0035391577 0.6021344146 0.94504895 5 169695849 169695938 90 + 1.325 1.291 -0.118
ENSG00000134516 E023 19.9488080 0.0011398578 0.0751370786 0.65765515 5 169698374 169698449 76 + 1.373 1.257 -0.404
ENSG00000134516 E024 21.5650581 0.0015425215 0.0749923386 0.65765515 5 169699382 169699458 77 + 1.404 1.291 -0.392
ENSG00000134516 E025 30.1243118 0.0024113886 0.0406195267 0.56101495 5 169700014 169700139 126 + 1.545 1.429 -0.396
ENSG00000134516 E026 29.1589345 0.0061160184 0.0005571918 0.07765887 5 169702303 169702427 125 + 1.572 1.352 -0.756
ENSG00000134516 E027 0.3748495 0.0168244885 0.5686878352   5 169702428 169702623 196 + 0.175 0.095 -1.026
ENSG00000134516 E028 0.0000000       5 169703949 169704075 127 +      
ENSG00000134516 E029 23.3829034 0.0005940000 0.0034299394 0.20623290 5 169708169 169708267 99 + 1.464 1.286 -0.617
ENSG00000134516 E030 19.9136498 0.0027812437 0.3265701170 0.88358683 5 169711935 169712007 73 + 1.350 1.286 -0.223
ENSG00000134516 E031 24.7019088 0.0009604772 0.3856365446 0.90055123 5 169712120 169712223 104 + 1.382 1.437 0.190
ENSG00000134516 E032 30.4971460 0.0038325394 0.4865919486 0.92316120 5 169714028 169714211 184 + 1.516 1.478 -0.131
ENSG00000134516 E033 24.2342779 0.0006375886 0.2455809704 0.84229171 5 169714360 169714457 98 + 1.433 1.366 -0.232
ENSG00000134516 E034 24.5579492 0.0008940068 0.6042661143 0.94526316 5 169716213 169716302 90 + 1.421 1.392 -0.098
ENSG00000134516 E035 26.1756080 0.0011293460 0.4771295392 0.92086897 5 169717384 169717484 101 + 1.452 1.413 -0.135
ENSG00000134516 E036 26.1822817 0.0021902473 0.4830826636 0.92296848 5 169718657 169718745 89 + 1.452 1.413 -0.135
ENSG00000134516 E037 21.4661665 0.0007657762 0.7550604266 0.97189212 5 169718746 169718791 46 + 1.359 1.342 -0.059
ENSG00000134516 E038 20.1063697 0.0009445786 0.6984257336 0.96424194 5 169747396 169747425 30 + 1.335 1.312 -0.079
ENSG00000134516 E039 27.0536274 0.0114058317 0.7653862346 0.97355432 5 169747426 169747504 79 + 1.437 1.460 0.080
ENSG00000134516 E040 22.6619862 0.0277393622 0.9397103161 0.99581299 5 169759705 169759775 71 + 1.377 1.370 -0.025
ENSG00000134516 E041 0.0000000       5 169761307 169761518 212 +      
ENSG00000134516 E042 28.7995360 0.0005089930 0.3020342972 0.87298017 5 169761519 169761625 107 + 1.499 1.445 -0.187
ENSG00000134516 E043 0.0000000       5 169779571 169780017 447 +      
ENSG00000134516 E044 30.8059297 0.0020561209 0.1843055390 0.80001227 5 169803058 169803206 149 + 1.535 1.464 -0.246
ENSG00000134516 E045 30.2699187 0.0004902101 0.3099745663 0.87573352 5 169840757 169840852 96 + 1.519 1.467 -0.179
ENSG00000134516 E046 0.3754325 0.0168337471 0.5682076876   5 169841401 169841535 135 + 0.175 0.095 -1.026
ENSG00000134516 E047 2.2188605 0.0100305332 0.9598794945   5 169875226 169875877 652 + 0.510 0.505 -0.026
ENSG00000134516 E048 1.5753146 0.0085561478 0.1792514521   5 169934652 169934871 220 + 0.300 0.505 1.144
ENSG00000134516 E049 18.5951124 0.0007772555 0.9264120388 0.99437046 5 169983068 169983107 40 + 1.288 1.297 0.032
ENSG00000134516 E050 21.1403105 0.0006727606 0.3205967113 0.88024353 5 169983108 169983166 59 + 1.373 1.312 -0.212
ENSG00000134516 E051 24.5260584 0.0016964670 0.9199692194 0.99352169 5 169985828 169985922 95 + 1.408 1.405 -0.011
ENSG00000134516 E052 27.6853602 0.0010825447 0.2738956090 0.85944983 5 169996086 169996164 79 + 1.485 1.425 -0.206
ENSG00000134516 E053 0.0000000       5 169997974 169998024 51 +      
ENSG00000134516 E054 0.2364085 0.2909688962 0.3176491939   5 170000031 170000471 441 + 0.000 0.173 10.173
ENSG00000134516 E055 31.5800692 0.0036323938 0.6836593716 0.96034172 5 170008497 170008597 101 + 1.523 1.502 -0.071
ENSG00000134516 E056 20.5579990 0.0007420135 0.7055019987 0.96635079 5 170008688 170008746 59 + 1.320 1.347 0.095
ENSG00000134516 E057 41.4129670 0.0038268120 0.9912632294 0.99796923 5 170018960 170019108 149 + 1.626 1.628 0.008
ENSG00000134516 E058 29.7588239 0.0025075052 0.5091976304 0.92923338 5 170027863 170027928 66 + 1.467 1.509 0.141
ENSG00000134516 E059 20.9932533 0.0095443107 0.3918556360 0.90085552 5 170027929 170027948 20 + 1.309 1.375 0.228
ENSG00000134516 E060 59.0026840 0.0002424466 0.2709354568 0.85803346 5 170034399 170034555 157 + 1.755 1.801 0.155
ENSG00000134516 E061 29.1812810 0.0024776645 0.8996076153 0.99065995 5 170036515 170036555 41 + 1.475 1.485 0.035
ENSG00000134516 E062 0.3638056 0.0167484959 0.5993453760   5 170040635 170041054 420 + 0.096 0.173 0.974
ENSG00000134516 E063 34.0236149 0.0047836690 0.8664757788 0.98709667 5 170041055 170041145 91 + 1.548 1.540 -0.026
ENSG00000134516 E064 39.8695530 0.0003679755 0.6567210557 0.95485122 5 170042013 170042132 120 + 1.600 1.623 0.081
ENSG00000134516 E065 39.1617149 0.0008708221 0.3006391663 0.87298017 5 170045816 170045905 90 + 1.626 1.578 -0.162
ENSG00000134516 E066 43.2822792 0.0073918977 0.2663850767 0.85542814 5 170047510 170047614 105 + 1.674 1.613 -0.207
ENSG00000134516 E067 62.5024333 0.0031648236 0.8541349758 0.98554103 5 170050256 170050397 142 + 1.805 1.799 -0.020
ENSG00000134516 E068 47.5371667 0.0003110106 0.8692011640 0.98750525 5 170055305 170055386 82 + 1.681 1.691 0.034
ENSG00000134516 E069 5.6585697 0.0030817798 0.8344435449 0.98302607 5 170055387 170056683 1297 + 0.811 0.836 0.100
ENSG00000134516 E070 49.6206165 0.0003186620 0.1498184515 0.77166206 5 170056684 170056768 85 + 1.672 1.736 0.218
ENSG00000134516 E071 10.7467731 0.0257407723 0.1092356563 0.71449342 5 170056769 170057579 811 + 0.976 1.152 0.641
ENSG00000134516 E072 50.8630209 0.0006895159 0.4094648199 0.90668701 5 170057580 170057666 87 + 1.730 1.697 -0.110
ENSG00000134516 E073 79.0828997 0.0002194536 0.3210690089 0.88074258 5 170067510 170067686 177 + 1.885 1.922 0.123
ENSG00000134516 E074 38.0166474 0.0007507354 0.5304722210 0.93339486 5 170069137 170069220 84 + 1.574 1.608 0.114
ENSG00000134516 E075 1.0813049 0.2646665255 0.2532887910   5 170075444 170075946 503 + 0.175 0.433 1.783
ENSG00000134516 E076 53.7030811 0.0013396641 0.4057799399 0.90492011 5 170075947 170076084 138 + 1.753 1.720 -0.112
ENSG00000134516 E077 58.2733470 0.0002755029 0.9697342511 0.99725686 5 170077710 170077837 128 + 1.772 1.773 0.005
ENSG00000134516 E078 89.5855515 0.0051524835 0.0224497128 0.46141145 5 170078975 170079146 172 + 1.905 2.007 0.343
ENSG00000134516 E079 1.0802507 0.0774708792 0.1217674883   5 170079147 170080162 1016 + 0.175 0.433 1.782
ENSG00000134516 E080 75.4383505 0.0026862529 0.0394466718 0.55648799 5 170080163 170080283 121 + 1.839 1.926 0.290
ENSG00000134516 E081 2.6453479 0.0053491122 0.0110639935   5 170080284 170081841 1558 + 0.351 0.712 1.740
ENSG00000134516 E082 52.6959283 0.0048794837 0.3120869965 0.87727291 5 170081842 170081928 87 + 1.703 1.757 0.183
ENSG00000134516 E083 41.2450577 0.0076359136 0.0428839287 0.56747496 5 170081929 170081984 56 + 1.563 1.684 0.415
ENSG00000134516 E084 185.2256224 0.0018355678 0.3935810102 0.90141230 5 170082796 170083382 587 + 2.257 2.283 0.087

Help

Please Click HERE to learn more details about the results from DEXseq.