ENSG00000135838

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000367553 ENSG00000135838 pgwt_inf pgKDN_inf NPL protein_coding protein_coding 32.75007 41.76507 38.16171 1.498695 2.331061 -0.1301386 5.495481 0.0000000 9.053350 0.0000000 3.9395828 9.8239006 0.21704167 0.000000 0.228325 0.228325 0.02539398 0.02539398 FALSE TRUE
ENST00000479721 ENSG00000135838 pgwt_inf pgKDN_inf NPL protein_coding protein_coding_CDS_not_defined 32.75007 41.76507 38.16171 1.498695 2.331061 -0.1301386 2.948110 4.9224621 3.452373 2.6742608 2.3694828 -0.5105468 0.07298333 0.112600 0.082375 -0.030225 0.88698240 0.02539398 FALSE FALSE
MSTRG.2374.11 ENSG00000135838 pgwt_inf pgKDN_inf NPL protein_coding   32.75007 41.76507 38.16171 1.498695 2.331061 -0.1301386 6.531111 10.4232719 9.170062 1.3519557 3.5725078 -0.1846158 0.16866667 0.248725 0.257275 0.008550 0.95327066 0.02539398 FALSE TRUE
MSTRG.2374.12 ENSG00000135838 pgwt_inf pgKDN_inf NPL protein_coding   32.75007 41.76507 38.16171 1.498695 2.331061 -0.1301386 4.893097 11.4936514 3.185640 1.0112123 1.9966533 -1.8479151 0.11946667 0.278400 0.080000 -0.198400 0.44174657 0.02539398 FALSE TRUE
MSTRG.2374.14 ENSG00000135838 pgwt_inf pgKDN_inf NPL protein_coding   32.75007 41.76507 38.16171 1.498695 2.331061 -0.1301386 2.026732 2.3298246 1.709855 0.9249935 0.8394962 -0.4441135 0.07242500 0.055000 0.045025 -0.009975 0.96485110 0.02539398 FALSE TRUE
MSTRG.2374.8 ENSG00000135838 pgwt_inf pgKDN_inf NPL protein_coding   32.75007 41.76507 38.16171 1.498695 2.331061 -0.1301386 1.194273 0.1931236 3.120352 0.1931236 0.7823847 3.9458952 0.03472500 0.005125 0.083550 0.078425 0.11354316 0.02539398 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000135838 E001 0.0000000       1 182789293 182789316 24 +      
ENSG00000135838 E002 0.2358817 0.0156869260 0.3040034193   1 182789317 182789448 132 + 0.000 0.163 10.431
ENSG00000135838 E003 0.1182043 0.0116665871 0.6330119105   1 182789449 182789552 104 + 0.000 0.089 11.513
ENSG00000135838 E004 0.2460161 0.0163128626 0.8980412995   1 182789553 182789585 33 + 0.103 0.089 -0.235
ENSG00000135838 E005 0.1278119 0.0122657551 0.4559934031   1 182789586 182789599 14 + 0.103 0.000 -12.542
ENSG00000135838 E006 0.7164061 0.0143906931 0.1370788582   1 182789600 182789736 137 + 0.103 0.329 2.087
ENSG00000135838 E007 0.3530882 0.0239191389 0.1403752571   1 182789737 182789768 32 + 0.000 0.226 12.962
ENSG00000135838 E008 0.2354107 0.0156725148 0.3039830057   1 182789769 182789772 4 + 0.000 0.163 12.451
ENSG00000135838 E009 0.7290475 0.0134541454 0.5357478345   1 182789773 182789782 10 + 0.186 0.281 0.765
ENSG00000135838 E010 8.8018637 0.0019422255 0.3426211954 0.88954777 1 182789783 182789805 23 + 0.942 1.032 0.333
ENSG00000135838 E011 7.7907026 0.0022757785 0.2038374417 0.81501370 1 182789806 182789904 99 + 1.004 0.880 -0.465
ENSG00000135838 E012 2.8853995 0.0195231243 0.0147559828   1 182791248 182791330 83 + 0.369 0.725 1.691
ENSG00000135838 E013 7.2330456 0.0025801578 0.0009695599 0.10721512 1 182791507 182792230 724 + 0.700 1.050 1.350
ENSG00000135838 E014 0.9761044 0.0122376134 0.6352872136   1 182792231 182792231 1 + 0.256 0.329 0.502
ENSG00000135838 E015 20.1608859 0.0007705654 0.7828864059 0.97619282 1 182792232 182792286 55 + 1.334 1.317 -0.059
ENSG00000135838 E016 1.5559670 0.0412527089 0.0277537154   1 182794258 182794349 92 + 0.186 0.544 2.224
ENSG00000135838 E017 0.9659435 0.0121821644 0.2277970392   1 182794350 182794355 6 + 0.186 0.373 1.350
ENSG00000135838 E018 23.0547518 0.0006744084 0.6319977276 0.94938873 1 182794356 182794439 84 + 1.365 1.395 0.104
ENSG00000135838 E019 1.7289490 0.0085096852 0.7611146742   1 182795730 182795840 111 + 0.458 0.413 -0.235
ENSG00000135838 E020 1.0714937 0.0128706322 0.0262030714   1 182798072 182798167 96 + 0.103 0.450 2.765
ENSG00000135838 E021 24.6120561 0.0007170497 0.5462210226 0.93549351 1 182803698 182803771 74 + 1.426 1.391 -0.120
ENSG00000135838 E022 35.3943605 0.0024913174 0.1648514008 0.78478232 1 182806145 182806232 88 + 1.596 1.525 -0.245
ENSG00000135838 E023 4.4909964 0.0031602394 0.0992124195 0.70259311 1 182806233 182806531 299 + 0.624 0.825 0.824
ENSG00000135838 E024 0.3535592 0.0242311639 0.1404506431   1 182806532 182806532 1 + 0.000 0.226 12.960
ENSG00000135838 E025 1.3422854 0.0157707779 0.5314402657   1 182809185 182809307 123 + 0.316 0.413 0.572
ENSG00000135838 E026 1.7137748 0.0084712877 0.8223665293   1 182809843 182809970 128 + 0.416 0.450 0.180
ENSG00000135838 E027 26.8001376 0.0006879342 0.8945243117 0.99043423 1 182812156 182812213 58 + 1.447 1.440 -0.023
ENSG00000135838 E028 31.7120783 0.0004844102 0.2128540822 0.82179929 1 182814783 182814858 76 + 1.479 1.545 0.226
ENSG00000135838 E029 28.7595905 0.0005749324 0.8291565412 0.98287690 1 182816714 182816806 93 + 1.479 1.468 -0.038
ENSG00000135838 E030 29.8633318 0.0008688811 0.7474578046 0.97034666 1 182818541 182818637 97 + 1.498 1.481 -0.057
ENSG00000135838 E031 21.5177979 0.0007398770 0.6801950102 0.95943461 1 182818638 182818689 52 + 1.365 1.340 -0.087
ENSG00000135838 E032 17.4691352 0.0008932115 0.6317033723 0.94927049 1 182818813 182818859 47 + 1.283 1.250 -0.113
ENSG00000135838 E033 12.1603435 0.0013159831 0.0153790651 0.40480771 1 182822115 182822199 85 + 1.210 1.013 -0.710
ENSG00000135838 E034 16.1384314 0.0273440122 0.5089808197 0.92923338 1 182825781 182825820 40 + 1.264 1.204 -0.213
ENSG00000135838 E035 9.2903920 0.0016125900 0.0003503077 0.05982696 1 182825821 182827020 1200 + 0.802 1.144 1.276
ENSG00000135838 E036 160.4074100 0.0013535239 0.5690197573 0.94003571 1 182828724 182829602 879 + 2.214 2.201 -0.043
ENSG00000135838 E037 91.1551998 0.0001675499 0.3424933920 0.88954777 1 182829603 182830398 796 + 1.978 1.951 -0.091

Help

Please Click HERE to learn more details about the results from DEXseq.