ENSG00000141551

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000269361 ENSG00000141551 pgwt_inf pgKDN_inf CSNK1D protein_coding nonsense_mediated_decay 112.5208 110.0851 102.1265 6.416947 5.010767 -0.1082527 21.295749 24.378616 21.886133 1.882344 3.125680 -0.1555318 0.19495833 0.226400 0.214400 -0.01200 0.99232178 0.03394213 TRUE TRUE
ENST00000314028 ENSG00000141551 pgwt_inf pgKDN_inf CSNK1D protein_coding protein_coding 112.5208 110.0851 102.1265 6.416947 5.010767 -0.1082527 8.132629 18.083015 3.593399 2.213824 3.593399 -2.3280025 0.07366667 0.163100 0.032700 -0.13040 0.03394213 0.03394213 FALSE TRUE
ENST00000392334 ENSG00000141551 pgwt_inf pgKDN_inf CSNK1D protein_coding protein_coding 112.5208 110.0851 102.1265 6.416947 5.010767 -0.1082527 28.564349 23.978826 33.374261 1.308209 4.067613 0.4768055 0.25965000 0.221675 0.332575 0.11090 0.82937025 0.03394213 FALSE TRUE
ENST00000581737 ENSG00000141551 pgwt_inf pgKDN_inf CSNK1D protein_coding retained_intron 112.5208 110.0851 102.1265 6.416947 5.010767 -0.1082527 10.644985 7.516687 9.794917 1.077603 4.025482 0.3814905 0.09244167 0.068325 0.096875 0.02855 1.00000000 0.03394213 FALSE FALSE
ENST00000582844 ENSG00000141551 pgwt_inf pgKDN_inf CSNK1D protein_coding protein_coding_CDS_not_defined 112.5208 110.0851 102.1265 6.416947 5.010767 -0.1082527 8.149827 1.196508 12.359285 1.196508 4.326974 3.3578529 0.07155833 0.009700 0.116000 0.10630 0.27947265 0.03394213 FALSE FALSE
ENST00000584913 ENSG00000141551 pgwt_inf pgKDN_inf CSNK1D protein_coding protein_coding_CDS_not_defined 112.5208 110.0851 102.1265 6.416947 5.010767 -0.1082527 15.645752 12.139866 9.227367 4.236781 2.652399 -0.3953868 0.13256667 0.105325 0.091225 -0.01410 0.98302076 0.03394213   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000141551 E001 0.0000000       17 82239023 82239168 146 -      
ENSG00000141551 E002 0.0000000       17 82239727 82239913 187 -      
ENSG00000141551 E003 0.0000000       17 82239914 82240062 149 -      
ENSG00000141551 E004 10.0187726 0.0015304871 4.739175e-01 0.920548758 17 82242667 82242672 6 - 1.004 1.072 0.247
ENSG00000141551 E005 333.9393091 0.0023245706 6.286746e-02 0.625734964 17 82242673 82244300 1628 - 2.501 2.543 0.142
ENSG00000141551 E006 14.1764555 0.0085562744 2.963115e-01 0.871454385 17 82244301 82244361 61 - 1.223 1.139 -0.298
ENSG00000141551 E007 12.3800592 0.0012440890 8.981229e-01 0.990659950 17 82244362 82244393 32 - 1.118 1.132 0.050
ENSG00000141551 E008 35.3732318 0.0004936226 5.782517e-01 0.941426724 17 82244394 82244490 97 - 1.572 1.548 -0.082
ENSG00000141551 E009 83.1415095 0.0002370478 3.556519e-01 0.894337089 17 82244491 82244644 154 - 1.938 1.912 -0.088
ENSG00000141551 E010 49.4106824 0.0003187733 2.418376e-01 0.839412001 17 82244645 82244679 35 - 1.672 1.726 0.182
ENSG00000141551 E011 42.3053301 0.0003657224 1.934110e-01 0.808555445 17 82244680 82244721 42 - 1.600 1.664 0.217
ENSG00000141551 E012 18.5868459 0.0045055608 4.283643e-01 0.913189173 17 82244722 82244831 110 - 1.257 1.318 0.215
ENSG00000141551 E013 1.8099681 0.0688174701 2.184109e-01   17 82244929 82245113 185 - 0.323 0.534 1.137
ENSG00000141551 E014 14.0778089 0.0011020645 7.326254e-01 0.969345029 17 82245976 82246017 42 - 1.161 1.191 0.107
ENSG00000141551 E015 23.0546003 0.0011671117 9.881980e-01 0.997969229 17 82246018 82246039 22 - 1.378 1.382 0.016
ENSG00000141551 E016 5.5260041 0.0523055407 8.293640e-01 0.982876904 17 82246040 82246197 158 - 0.831 0.798 -0.129
ENSG00000141551 E017 4.7293548 0.0031964093 8.964247e-02 0.686763963 17 82246198 82246317 120 - 0.634 0.842 0.847
ENSG00000141551 E018 4.0207548 0.0046126944 3.684973e-01 0.897818293 17 82246318 82246433 116 - 0.634 0.750 0.484
ENSG00000141551 E019 36.7623706 0.0004862685 2.544221e-05 0.008842781 17 82246434 82248874 2441 - 1.447 1.664 0.742
ENSG00000141551 E020 59.2661980 0.0002613919 8.170370e-01 0.982170731 17 82248875 82249014 140 - 1.782 1.777 -0.017
ENSG00000141551 E021 0.9533612 0.0410924642 6.223426e-02   17 82249015 82249238 224 - 0.106 0.405 2.485
ENSG00000141551 E022 0.0000000       17 82249239 82249430 192 -      
ENSG00000141551 E023 0.0000000       17 82249431 82249488 58 -      
ENSG00000141551 E024 0.0000000       17 82249489 82249577 89 -      
ENSG00000141551 E025 0.0000000       17 82249578 82249602 25 -      
ENSG00000141551 E026 0.0000000       17 82249603 82249697 95 -      
ENSG00000141551 E027 0.0000000       17 82249698 82250179 482 -      
ENSG00000141551 E028 0.0000000       17 82251379 82251527 149 -      
ENSG00000141551 E029 27.7892059 0.0007459316 4.185742e-01 0.909767454 17 82252434 82252496 63 - 1.480 1.438 -0.144
ENSG00000141551 E030 38.5289054 0.0005555708 8.921967e-01 0.990434229 17 82252497 82252527 31 - 1.597 1.595 -0.009
ENSG00000141551 E031 57.7185372 0.0003074538 6.476061e-03 0.285972006 17 82252528 82252604 77 - 1.820 1.717 -0.348
ENSG00000141551 E032 99.6883059 0.0001961077 1.681139e-03 0.143219640 17 82253016 82253215 200 - 2.047 1.958 -0.298
ENSG00000141551 E033 19.7032524 0.0008023991 2.512808e-01 0.846374132 17 82253216 82253219 4 - 1.352 1.280 -0.251
ENSG00000141551 E034 28.7436290 0.0005092100 5.491012e-01 0.936444571 17 82253220 82253244 25 - 1.488 1.459 -0.101
ENSG00000141551 E035 9.9036390 0.0063327761 2.063425e-03 0.157361018 17 82253245 82254679 1435 - 0.849 1.153 1.124
ENSG00000141551 E036 0.7295119 0.0142811700 5.905742e-01   17 82255130 82255163 34 - 0.191 0.274 0.677
ENSG00000141551 E037 0.6011727 0.0151765686 2.664432e-01   17 82255164 82255186 23 - 0.106 0.274 1.677
ENSG00000141551 E038 1.2322853 0.0099694026 7.163731e-01   17 82255187 82255328 142 - 0.376 0.322 -0.323
ENSG00000141551 E039 1.5758280 0.0087113716 3.274787e-01   17 82255329 82255428 100 - 0.323 0.475 0.847
ENSG00000141551 E040 30.5187485 0.0004727546 8.919077e-01 0.990434229 17 82255429 82255437 9 - 1.492 1.503 0.038
ENSG00000141551 E041 53.0197582 0.0003261426 6.234430e-01 0.948287413 17 82255438 82255577 140 - 1.740 1.724 -0.055
ENSG00000141551 E042 0.5996874 0.0143810757 2.660270e-01   17 82265300 82265685 386 - 0.106 0.274 1.677
ENSG00000141551 E043 36.0471723 0.0004258424 2.181912e-01 0.824629893 17 82265686 82265796 111 - 1.597 1.540 -0.195
ENSG00000141551 E044 0.0000000       17 82266708 82266724 17 -      
ENSG00000141551 E045 0.1293601 0.0123437242 4.250881e-01   17 82266725 82266891 167 - 0.106 0.000 -10.578
ENSG00000141551 E046 0.0000000       17 82266892 82266894 3 -      
ENSG00000141551 E047 0.2576729 0.0161041297 1.725482e-01   17 82266983 82267032 50 - 0.191 0.000 -11.507
ENSG00000141551 E048 0.6234778 0.0204809069 4.837394e-01   17 82272070 82272316 247 - 0.262 0.158 -0.908
ENSG00000141551 E049 0.0000000       17 82273091 82273136 46 -      
ENSG00000141551 E050 0.7405922 0.0144359078 7.777170e-01   17 82273137 82273305 169 - 0.262 0.220 -0.323
ENSG00000141551 E051 45.0518858 0.0073433775 2.456850e-02 0.481213464 17 82273306 82273700 395 - 1.723 1.602 -0.410

Help

Please Click HERE to learn more details about the results from DEXseq.