ENSG00000147813

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000449291 ENSG00000147813 pgwt_inf pgKDN_inf NAPRT protein_coding protein_coding 106.5485 71.32632 81.63276 2.946425 2.007707 0.1946881 49.584525 31.256551 51.996211 0.8023520 1.9485395 0.7340639 0.49015833 0.441450 0.636800 0.195350 0.02322556 0.02322556 FALSE TRUE
ENST00000462059 ENSG00000147813 pgwt_inf pgKDN_inf NAPRT protein_coding retained_intron 106.5485 71.32632 81.63276 2.946425 2.007707 0.1946881 7.438280 8.778139 5.482902 1.1578046 1.9980496 -0.6779891 0.07885000 0.122925 0.068325 -0.054600 0.88698240 0.02322556 TRUE TRUE
ENST00000464332 ENSG00000147813 pgwt_inf pgKDN_inf NAPRT protein_coding retained_intron 106.5485 71.32632 81.63276 2.946425 2.007707 0.1946881 15.877393 9.565761 6.170030 1.5147907 0.4354295 -0.6317732 0.13525000 0.137375 0.075650 -0.061725 0.83099515 0.02322556 FALSE TRUE
ENST00000480946 ENSG00000147813 pgwt_inf pgKDN_inf NAPRT protein_coding retained_intron 106.5485 71.32632 81.63276 2.946425 2.007707 0.1946881 8.284235 3.918309 4.653146 0.4266255 0.6160599 0.2473950 0.07036667 0.055825 0.056825 0.001000 1.00000000 0.02322556 TRUE TRUE
MSTRG.28335.1 ENSG00000147813 pgwt_inf pgKDN_inf NAPRT protein_coding   106.5485 71.32632 81.63276 2.946425 2.007707 0.1946881 6.060355 3.309305 4.256712 1.0072303 1.2223459 0.3622436 0.05428333 0.046550 0.053275 0.006725 1.00000000 0.02322556 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000147813 E001 0.0000000       8 143574754 143574774 21 -      
ENSG00000147813 E002 0.0000000       8 143574775 143574784 10 -      
ENSG00000147813 E003 0.0000000       8 143574785 143574785 1 -      
ENSG00000147813 E004 0.0000000       8 143574786 143574786 1 -      
ENSG00000147813 E005 0.0000000       8 143574787 143574787 1 -      
ENSG00000147813 E006 10.8557688 0.0017646416 0.5461771868 0.93548794 8 143574788 143574900 113 - 1.047 1.100 0.191
ENSG00000147813 E007 2.4106092 0.0106459563 0.0120875584   8 143574901 143574985 85 - 0.333 0.694 1.776
ENSG00000147813 E008 2.3806872 0.0085808178 0.1859987913   8 143574986 143575093 108 - 0.602 0.411 -0.924
ENSG00000147813 E009 3.4099114 0.0047016461 0.0657838428   8 143575094 143575190 97 - 0.519 0.759 1.039
ENSG00000147813 E010 11.0987678 0.0015139047 0.6860970206 0.96082515 8 143575191 143575229 39 - 1.065 1.100 0.127
ENSG00000147813 E011 46.1629362 0.0003372508 0.0886740837 0.68576214 8 143575230 143575345 116 - 1.702 1.629 -0.247
ENSG00000147813 E012 4.0600583 0.0036084114 0.5884530728 0.94356045 8 143575346 143575422 77 - 0.671 0.738 0.279
ENSG00000147813 E013 31.0192957 0.0005094822 0.2043070204 0.81504215 8 143575423 143575431 9 - 1.531 1.465 -0.227
ENSG00000147813 E014 59.3685790 0.0002905576 0.1848863637 0.80076334 8 143575432 143575525 94 - 1.799 1.750 -0.166
ENSG00000147813 E015 0.1177530 0.0116355469 0.4722388619   8 143575600 143575621 22 - 0.000 0.101 9.495
ENSG00000147813 E016 28.2879895 0.0004950138 0.7949733270 0.97893822 8 143575622 143575622 1 - 1.457 1.473 0.052
ENSG00000147813 E017 55.5891159 0.0003755498 0.4991076456 0.92574377 8 143575623 143575702 80 - 1.761 1.736 -0.086
ENSG00000147813 E018 58.8914148 0.0003389574 0.7352045943 0.96967057 8 143576078 143576162 85 - 1.780 1.768 -0.040
ENSG00000147813 E019 14.1269905 0.0037879589 0.0003971622 0.06449807 8 143576163 143576431 269 - 1.029 1.311 1.008
ENSG00000147813 E020 31.8271131 0.0004688324 0.4197980918 0.91039676 8 143576432 143576439 8 - 1.494 1.537 0.146
ENSG00000147813 E021 52.3351532 0.0002872852 0.4344332303 0.91553945 8 143576440 143576572 133 - 1.710 1.742 0.109
ENSG00000147813 E022 2.8192748 0.0052115779 0.3547675658   8 143576646 143576842 197 - 0.519 0.646 0.570
ENSG00000147813 E023 0.0000000       8 143576843 143576942 100 -      
ENSG00000147813 E024 0.0000000       8 143576943 143577061 119 -      
ENSG00000147813 E025 0.0000000       8 143577062 143577177 116 -      
ENSG00000147813 E026 0.0000000       8 143577178 143577266 89 -      
ENSG00000147813 E027 0.0000000       8 143577267 143577268 2 -      
ENSG00000147813 E028 0.2354305 0.0157192649 0.2008972644   8 143577269 143577399 131 - 0.000 0.184 10.495
ENSG00000147813 E029 22.8763439 0.0006193756 0.9410979137 0.99581299 8 143577657 143577739 83 - 1.377 1.374 -0.012
ENSG00000147813 E030 0.6113143 0.0145414545 0.5555619939   8 143577740 143577815 76 - 0.165 0.253 0.776
ENSG00000147813 E031 29.1444344 0.0006113574 0.2408337979 0.83941200 8 143577816 143577860 45 - 1.504 1.441 -0.217
ENSG00000147813 E032 39.4678358 0.0004017850 0.7187319924 0.96805844 8 143577861 143577943 83 - 1.612 1.596 -0.054
ENSG00000147813 E033 8.0589619 0.0017644076 0.0250589989 0.48384883 8 143577944 143578092 149 - 0.845 1.062 0.813
ENSG00000147813 E034 71.0968007 0.0002397060 0.9421310176 0.99581299 8 143578093 143578352 260 - 1.856 1.854 -0.005
ENSG00000147813 E035 0.0000000       8 143578586 143578649 64 -      

Help

Please Click HERE to learn more details about the results from DEXseq.