ENSG00000163874

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000373087 ENSG00000163874 pgwt_inf pgKDN_inf ZC3H12A protein_coding protein_coding 61.58831 101.1136 68.47329 3.055776 1.599561 -0.5622965 29.291745 52.310363 26.002151 4.9380479 6.6721122 -1.008187 0.50976667 0.521775 0.378100 -0.143675 8.534755e-01 1.435323e-05 FALSE  
ENST00000471012 ENSG00000163874 pgwt_inf pgKDN_inf ZC3H12A protein_coding protein_coding 61.58831 101.1136 68.47329 3.055776 1.599561 -0.5622965 3.185909 8.666307 0.000000 2.7293726 0.0000000 -9.760937 0.04613333 0.083550 0.000000 -0.083550 1.435323e-05 1.435323e-05 FALSE  
MSTRG.709.1 ENSG00000163874 pgwt_inf pgKDN_inf ZC3H12A protein_coding   61.58831 101.1136 68.47329 3.055776 1.599561 -0.5622965 19.720051 25.785473 31.764071 4.5150140 6.5371758 0.300732 0.27689167 0.253175 0.466325 0.213150 6.282122e-01 1.435323e-05 FALSE  
MSTRG.709.4 ENSG00000163874 pgwt_inf pgKDN_inf ZC3H12A protein_coding   61.58831 101.1136 68.47329 3.055776 1.599561 -0.5622965 4.903812 8.190711 4.755442 0.9418791 0.8862812 -0.783139 0.08850833 0.080500 0.069450 -0.011050 8.997290e-01 1.435323e-05 TRUE  
MSTRG.709.5 ENSG00000163874 pgwt_inf pgKDN_inf ZC3H12A protein_coding   61.58831 101.1136 68.47329 3.055776 1.599561 -0.5622965 3.306887 5.812358 2.760329 0.3574726 0.1591837 -1.071546 0.06229167 0.057375 0.040525 -0.016850 8.869824e-01 1.435323e-05 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000163874 E001 0.1293601 1.234167e-02 3.338114e-01   1 37474530 37474579 50 + 0.117 0.000 -9.688
ENSG00000163874 E002 0.1293601 1.234167e-02 3.338114e-01   1 37474580 37474583 4 + 0.117 0.000 -11.460
ENSG00000163874 E003 1.0953363 7.581182e-02 7.717264e-01   1 37474584 37474587 4 + 0.285 0.338 0.340
ENSG00000163874 E004 15.0365237 1.329309e-02 6.839977e-01 9.603530e-01 1 37474588 37474629 42 + 1.217 1.185 -0.115
ENSG00000163874 E005 8.7520105 2.661872e-02 4.119293e-01 9.070674e-01 1 37475459 37475461 3 + 0.926 1.017 0.339
ENSG00000163874 E006 155.8208008 1.070852e-04 5.998572e-01 9.443461e-01 1 37475462 37475939 478 + 2.195 2.183 -0.041
ENSG00000163874 E007 94.9160772 2.102138e-04 5.130798e-08 8.268762e-05 1 37475940 37479998 4059 + 1.862 2.038 0.590
ENSG00000163874 E008 6.6130683 3.839458e-03 5.708032e-01 9.402755e-01 1 37479999 37480229 231 + 0.910 0.850 -0.230
ENSG00000163874 E009 4.1017307 3.687508e-03 1.368321e-01 7.525768e-01 1 37480230 37480289 60 + 0.578 0.771 0.813
ENSG00000163874 E010 68.4073073 2.906053e-04 5.970253e-01 9.440140e-01 1 37480290 37480429 140 + 1.845 1.826 -0.065
ENSG00000163874 E011 25.4574725 1.111561e-02 4.367110e-02 5.715769e-01 1 37480430 37481600 1171 + 1.319 1.471 0.529
ENSG00000163874 E012 52.7562133 2.705437e-04 3.841772e-01 9.003504e-01 1 37481601 37481689 89 + 1.701 1.738 0.125
ENSG00000163874 E013 99.1003097 1.671651e-04 3.777726e-01 8.986717e-01 1 37481690 37481835 146 + 1.977 2.004 0.091
ENSG00000163874 E014 22.0256712 2.392457e-03 1.400975e-02 3.930006e-01 1 37481836 37482349 514 + 1.249 1.416 0.585
ENSG00000163874 E015 5.1006799 2.998575e-03 4.733713e-01 9.204192e-01 1 37482350 37482353 4 + 0.727 0.812 0.339
ENSG00000163874 E016 9.2904248 3.278253e-03 7.205366e-01 9.681439e-01 1 37482354 37482433 80 + 1.025 0.992 -0.123
ENSG00000163874 E017 91.6787382 1.723096e-04 5.805985e-03 2.683663e-01 1 37482434 37482540 107 + 2.008 1.923 -0.288
ENSG00000163874 E018 1.7894213 9.270608e-03 3.154619e-02   1 37482541 37482602 62 + 0.209 0.550 2.040
ENSG00000163874 E019 700.4853510 7.911736e-05 1.754444e-03 1.461681e-01 1 37482737 37484377 1641 + 2.854 2.828 -0.086

Help

Please Click HERE to learn more details about the results from DEXseq.