ENSG00000171522

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000302472 ENSG00000171522 pgwt_inf pgKDN_inf PTGER4 protein_coding protein_coding 79.03457 94.94011 103.2869 0.7690142 0.7869122 0.1215558 45.790254 59.931009 56.932251 1.522589 3.130804 -0.07404385 0.57085000 0.631375 0.551475 -0.079900 0.82937025 0.04227205 FALSE  
ENST00000512578 ENSG00000171522 pgwt_inf pgKDN_inf PTGER4 protein_coding protein_coding_CDS_not_defined 79.03457 94.94011 103.2869 0.7690142 0.7869122 0.1215558 5.210333 3.011950 6.474346 3.011950 6.474346 1.10148108 0.08623333 0.032175 0.061700 0.029525 1.00000000 0.04227205 FALSE  
ENST00000513635 ENSG00000171522 pgwt_inf pgKDN_inf PTGER4 protein_coding protein_coding_CDS_not_defined 79.03457 94.94011 103.2869 0.7690142 0.7869122 0.1215558 2.517273 0.000000 7.131804 0.000000 3.090829 9.48014477 0.02675833 0.000000 0.068625 0.068625 0.05568496 0.04227205 FALSE  
MSTRG.22817.5 ENSG00000171522 pgwt_inf pgKDN_inf PTGER4 protein_coding   79.03457 94.94011 103.2869 0.7690142 0.7869122 0.1215558 3.268858 7.447721 0.000000 3.075728 0.000000 -9.54259105 0.04564167 0.077850 0.000000 -0.077850 0.04227205 0.04227205 FALSE  
MSTRG.22817.6 ENSG00000171522 pgwt_inf pgKDN_inf PTGER4 protein_coding   79.03457 94.94011 103.2869 0.7690142 0.7869122 0.1215558 20.782408 21.940925 31.705817 3.727749 6.384015 0.53092075 0.25137500 0.231200 0.308100 0.076900 0.88698240 0.04227205 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000171522 E001 1.9921420 0.0090682987 2.590424e-01   5 40679915 40679929 15 + 0.550 0.385 -0.838
ENSG00000171522 E002 152.1838165 0.0018326232 1.657367e-01 0.786257611 5 40679930 40680478 549 + 2.165 2.205 0.135
ENSG00000171522 E003 189.4652664 0.0001400671 4.427520e-03 0.236251528 5 40680951 40681489 539 + 2.249 2.309 0.203
ENSG00000171522 E004 74.8559954 0.0030475303 4.689140e-01 0.920058829 5 40681490 40681686 197 + 1.864 1.895 0.103
ENSG00000171522 E005 18.5397545 0.0100285917 5.077317e-01 0.928422123 5 40681687 40681701 15 + 1.264 1.317 0.187
ENSG00000171522 E006 59.6647906 0.0039467015 2.794372e-01 0.862325079 5 40681702 40681860 159 + 1.757 1.808 0.173
ENSG00000171522 E007 0.7598269 0.0144427795 7.815759e-02   5 40685371 40685391 21 + 0.357 0.093 -2.419
ENSG00000171522 E008 3.6334030 0.0071436406 4.771764e-02   5 40685392 40685483 92 + 0.518 0.778 1.121
ENSG00000171522 E009 3.8881444 0.0360139508 1.701819e-01 0.789742895 5 40685484 40685730 247 + 0.580 0.778 0.832
ENSG00000171522 E010 5.2474871 0.0389780908 3.510636e-01 0.890982358 5 40685731 40685788 58 + 0.727 0.856 0.512
ENSG00000171522 E011 1005.1818339 0.0000895174 7.729626e-06 0.003905286 5 40691779 40693735 1957 + 3.015 2.990 -0.083

Help

Please Click HERE to learn more details about the results from DEXseq.