ENSG00000182446

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000574964 ENSG00000182446 pgwt_inf pgKDN_inf NPLOC4 protein_coding protein_coding_CDS_not_defined 43.12926 43.97327 41.94467 2.396453 1.256752 -0.06812315 2.371761 2.496653 2.424963 1.451629 0.8804849 -0.04186249 0.05658333 0.055125 0.059000 0.003875 0.88698240 0.03972817 TRUE FALSE
ENST00000705719 ENSG00000182446 pgwt_inf pgKDN_inf NPLOC4 protein_coding protein_coding 43.12926 43.97327 41.94467 2.396453 1.256752 -0.06812315 21.741792 21.481635 32.629920 4.569309 1.6668509 0.60286228 0.52429167 0.503900 0.782775 0.278875 0.50392605 0.03972817 FALSE TRUE
MSTRG.13459.1 ENSG00000182446 pgwt_inf pgKDN_inf NPLOC4 protein_coding   43.12926 43.97327 41.94467 2.396453 1.256752 -0.06812315 7.899234 9.263957 0.000000 4.423761 0.0000000 -9.85704126 0.17138333 0.201925 0.000000 -0.201925 0.03972817 0.03972817 FALSE TRUE
MSTRG.13459.10 ENSG00000182446 pgwt_inf pgKDN_inf NPLOC4 protein_coding   43.12926 43.97327 41.94467 2.396453 1.256752 -0.06812315 2.233940 2.087661 1.324811 0.190378 0.2701022 -0.65214578 0.05252500 0.047375 0.032275 -0.015100 0.88698240 0.03972817 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000182446 E001 0.1177332 0.0116906058 0.5985940428   17 81556866 81556886 21 - 0.000 0.091 9.163
ENSG00000182446 E002 1.7137121 0.0076537179 0.7419276543   17 81556887 81556898 12 - 0.407 0.458 0.267
ENSG00000182446 E003 400.1054910 0.0004464658 0.0511378540 0.59439167 17 81556899 81558788 1890 - 2.588 2.618 0.099
ENSG00000182446 E004 55.4149099 0.0048107063 0.6445376144 0.95159482 17 81558789 81559013 225 - 1.738 1.764 0.089
ENSG00000182446 E005 20.1043506 0.0036062812 0.4671353461 0.91993583 17 81559014 81559063 50 - 1.348 1.300 -0.166
ENSG00000182446 E006 15.2758229 0.0115162844 0.7151949734 0.96779455 17 81559064 81559090 27 - 1.226 1.197 -0.102
ENSG00000182446 E007 19.4442181 0.0007551521 0.8406118683 0.98406518 17 81559091 81559124 34 - 1.316 1.305 -0.038
ENSG00000182446 E008 23.6718721 0.0006363321 0.4485958468 0.91695438 17 81559125 81559181 57 - 1.367 1.416 0.167
ENSG00000182446 E009 29.9239233 0.0005016209 0.3438201071 0.88954777 17 81559182 81559267 86 - 1.462 1.516 0.185
ENSG00000182446 E010 27.5515243 0.0067522999 0.9699848148 0.99725686 17 81559268 81559315 48 - 1.455 1.457 0.007
ENSG00000182446 E011 34.4068470 0.0011610592 0.3431731105 0.88954777 17 81559316 81559395 80 - 1.572 1.525 -0.158
ENSG00000182446 E012 21.1584786 0.0006889091 0.0649302451 0.63154212 17 81559396 81559416 21 - 1.400 1.284 -0.402
ENSG00000182446 E013 5.2405122 0.0342797158 0.2690952138 0.85781061 17 81560562 81560629 68 - 0.712 0.864 0.607
ENSG00000182446 E014 6.0521850 0.0769061227 0.1063093623 0.71258811 17 81560630 81560720 91 - 0.689 0.963 1.074
ENSG00000182446 E015 38.1010678 0.0024003864 0.0001264409 0.02921848 17 81560721 81561765 1045 - 1.478 1.682 0.696
ENSG00000182446 E016 6.9688438 0.0141326257 0.3289832177 0.88505079 17 81561766 81562106 341 - 0.843 0.952 0.416
ENSG00000182446 E017 16.6509804 0.0009147944 0.0022642388 0.16440362 17 81562107 81563412 1306 - 1.120 1.344 0.789
ENSG00000182446 E018 1.9698698 0.0077515339 0.8318963562   17 81563413 81563568 156 - 0.488 0.458 -0.148
ENSG00000182446 E019 5.7348296 0.0302032329 0.2774573685 0.86142935 17 81563569 81563920 352 - 0.753 0.891 0.540
ENSG00000182446 E020 3.5262426 0.0054873170 0.1706726695   17 81563921 81563979 59 - 0.555 0.736 0.778
ENSG00000182446 E021 2.9034751 0.0187838890 0.0849829554   17 81563980 81564212 233 - 0.449 0.697 1.132
ENSG00000182446 E022 1.1144461 0.2706335048 0.6849883879   17 81564213 81564246 34 - 0.361 0.287 -0.468
ENSG00000182446 E023 7.1646270 0.0236157957 0.0442086018 0.57312057 17 81564247 81564908 662 - 0.773 1.015 0.926
ENSG00000182446 E024 8.0718648 0.0017924324 0.3029588167 0.87298017 17 81564909 81565504 596 - 0.903 1.005 0.383
ENSG00000182446 E025 27.4949318 0.0006256813 0.3827213303 0.90029493 17 81565505 81565607 103 - 1.478 1.431 -0.161
ENSG00000182446 E026 0.0000000       17 81566388 81566470 83 -      
ENSG00000182446 E027 0.4819344 0.0153869321 0.3743314979   17 81566471 81566635 165 - 0.100 0.231 1.437
ENSG00000182446 E028 0.0000000       17 81566875 81566985 111 -      
ENSG00000182446 E029 29.8767717 0.0005313073 0.0046286448 0.24078312 17 81567417 81567533 117 - 1.559 1.408 -0.521
ENSG00000182446 E030 0.0000000       17 81567934 81567953 20 -      
ENSG00000182446 E031 0.0000000       17 81567954 81568075 122 -      
ENSG00000182446 E032 34.4658944 0.0004384669 0.0032652267 0.20164320 17 81569016 81569111 96 - 1.617 1.471 -0.503
ENSG00000182446 E033 28.4418861 0.0011647339 0.0667698075 0.63700112 17 81572017 81572088 72 - 1.517 1.416 -0.349
ENSG00000182446 E034 0.2459969 0.0165513570 0.9331993813   17 81572089 81572108 20 - 0.100 0.091 -0.148
ENSG00000182446 E035 0.1182043 0.0116743213 0.5986445722   17 81588091 81588187 97 - 0.000 0.091 11.497
ENSG00000182446 E036 36.5864056 0.0004092474 0.4477678118 0.91695438 17 81588944 81589104 161 - 1.592 1.558 -0.119
ENSG00000182446 E037 28.4241537 0.0008418147 0.2060468266 0.81648861 17 81596116 81596242 127 - 1.430 1.504 0.253
ENSG00000182446 E038 21.9048529 0.0043597188 0.9036917388 0.99143282 17 81597245 81597316 72 - 1.362 1.357 -0.018
ENSG00000182446 E039 0.0000000       17 81597317 81597319 3 -      
ENSG00000182446 E040 24.3499424 0.0006485177 0.1247187184 0.73698714 17 81600341 81600427 87 - 1.447 1.357 -0.309
ENSG00000182446 E041 14.9449733 0.0012564425 0.3907698268 0.90057833 17 81604548 81604571 24 - 1.232 1.170 -0.220
ENSG00000182446 E042 18.4168460 0.0008792745 0.5226005435 0.93150282 17 81604572 81604608 37 - 1.264 1.310 0.161
ENSG00000182446 E043 22.0793656 0.0006574231 0.4269795758 0.91263954 17 81604609 81604663 55 - 1.386 1.339 -0.164
ENSG00000182446 E044 25.2428383 0.0005466495 0.6711558826 0.95698492 17 81604664 81604727 64 - 1.430 1.408 -0.078
ENSG00000182446 E045 33.0922702 0.0019234858 0.9274154306 0.99451206 17 81606691 81606814 124 - 1.534 1.531 -0.008
ENSG00000182446 E046 19.1430442 0.0007970443 0.2195272627 0.82584996 17 81608728 81608800 73 - 1.342 1.263 -0.278
ENSG00000182446 E047 9.1288551 0.0015843398 0.4890465762 0.92319705 17 81608801 81608810 10 - 1.036 0.974 -0.226
ENSG00000182446 E048 10.1123285 0.0021913873 0.4842340364 0.92296848 17 81608811 81608822 12 - 1.075 1.015 -0.218
ENSG00000182446 E049 0.2470867 0.0165984541 0.9328296729   17 81608823 81608919 97 - 0.100 0.091 -0.148
ENSG00000182446 E050 15.3441581 0.0009360423 0.1362856696 0.75161671 17 81610210 81610258 49 - 1.264 1.156 -0.381
ENSG00000182446 E051 0.2571654 0.0162070060 0.2076685413   17 81612679 81612873 195 - 0.181 0.000 -13.361
ENSG00000182446 E052 0.0000000       17 81613050 81613125 76 -      
ENSG00000182446 E053 32.2298521 0.0006571709 0.1941947026 0.80887759 17 81613318 81613494 177 - 1.553 1.487 -0.225
ENSG00000182446 E054 0.0000000       17 81614318 81614381 64 -      
ENSG00000182446 E055 22.8965585 0.0006441990 0.7666754809 0.97355432 17 81622166 81622278 113 - 1.386 1.370 -0.055
ENSG00000182446 E056 0.0000000       17 81623673 81623706 34 -      
ENSG00000182446 E057 20.0473221 0.0007100911 0.0751898336 0.65765515 17 81629725 81629805 81 - 1.377 1.263 -0.398
ENSG00000182446 E058 0.0000000       17 81629864 81629875 12 -      
ENSG00000182446 E059 0.0000000       17 81636397 81636478 82 -      
ENSG00000182446 E060 23.6780384 0.0169479169 0.5825348424 0.94186773 17 81636916 81637112 197 - 1.413 1.370 -0.148
ENSG00000182446 E061 0.0000000       17 81648430 81648465 36 -      

Help

Please Click HERE to learn more details about the results from DEXseq.