ENSG00000187815

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000372705 ENSG00000187815 pgwt_inf pgKDN_inf ZFP69 protein_coding protein_coding 49.33444 53.2824 54.07385 1.287719 2.917176 0.02126802 15.969756 13.692083 19.5867063 1.1976024 2.0884168 0.51621597 0.32458333 0.256525 0.360875 0.104350 8.293702e-01 2.023665e-07 FALSE TRUE
ENST00000372706 ENSG00000187815 pgwt_inf pgKDN_inf ZFP69 protein_coding protein_coding 49.33444 53.2824 54.07385 1.287719 2.917176 0.02126802 4.272839 10.052028 0.0000000 5.9171187 0.0000000 -9.97470543 0.08644167 0.188600 0.000000 -0.188600 8.869824e-01 2.023665e-07 FALSE TRUE
ENST00000482712 ENSG00000187815 pgwt_inf pgKDN_inf ZFP69 protein_coding protein_coding_CDS_not_defined 49.33444 53.2824 54.07385 1.287719 2.917176 0.02126802 7.339182 6.196617 6.4938635 1.0597994 1.3848412 0.06748991 0.15306667 0.115500 0.117725 0.002225 1.000000e+00 2.023665e-07   FALSE
MSTRG.783.1 ENSG00000187815 pgwt_inf pgKDN_inf ZFP69 protein_coding   49.33444 53.2824 54.07385 1.287719 2.917176 0.02126802 2.613587 7.232009 0.4405166 0.5779308 0.4405166 -4.00673758 0.04962500 0.136250 0.007825 -0.128425 1.244381e-02 2.023665e-07 FALSE TRUE
MSTRG.783.3 ENSG00000187815 pgwt_inf pgKDN_inf ZFP69 protein_coding   49.33444 53.2824 54.07385 1.287719 2.917176 0.02126802 2.778651 0.000000 8.3359541 0.0000000 3.0550964 9.70493318 0.05312500 0.000000 0.159375 0.159375 3.098542e-02 2.023665e-07 FALSE TRUE
MSTRG.783.4 ENSG00000187815 pgwt_inf pgKDN_inf ZFP69 protein_coding   49.33444 53.2824 54.07385 1.287719 2.917176 0.02126802 3.448122 5.313270 2.1576340 0.4740570 0.8605110 -1.29619149 0.07041667 0.099900 0.037625 -0.062275 8.293702e-01 2.023665e-07 FALSE TRUE
MSTRG.783.5 ENSG00000187815 pgwt_inf pgKDN_inf ZFP69 protein_coding   49.33444 53.2824 54.07385 1.287719 2.917176 0.02126802 5.521390 0.000000 11.3830560 0.0000000 3.7225738 10.15393907 0.10929167 0.000000 0.201575 0.201575 2.023665e-07 2.023665e-07 FALSE TRUE
MSTRG.783.6 ENSG00000187815 pgwt_inf pgKDN_inf ZFP69 protein_coding   49.33444 53.2824 54.07385 1.287719 2.917176 0.02126802 5.488645 10.796391 3.3627683 6.4248124 3.3627683 -1.67987970 0.11225833 0.203275 0.071450 -0.131825 8.869824e-01 2.023665e-07 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000187815 E001 0.8359647 2.082740e-01 0.1322131330   1 40477149 40477222 74 + 0.101 0.377 2.397
ENSG00000187815 E002 0.4818786 3.260846e-02 0.3916061313   1 40477223 40477229 7 + 0.101 0.228 1.397
ENSG00000187815 E003 0.4712924 1.623010e-02 0.0612894550   1 40477230 40477246 17 + 0.000 0.284 11.250
ENSG00000187815 E004 1.0069070 1.204285e-02 0.1067312986   1 40477247 40477289 43 + 0.411 0.165 -1.773
ENSG00000187815 E005 2.1113930 1.817351e-02 0.3329155868   1 40477290 40477316 27 + 0.560 0.418 -0.703
ENSG00000187815 E006 32.8577700 1.104749e-03 0.3309269294 0.88609468 1 40477317 40477629 313 + 1.502 1.554 0.180
ENSG00000187815 E007 57.1948852 2.760928e-04 0.4788261645 0.92156997 1 40477630 40477894 265 + 1.750 1.779 0.097
ENSG00000187815 E008 25.4936755 2.662810e-03 0.0001785931 0.03733726 1 40477895 40479015 1121 + 1.288 1.522 0.812
ENSG00000187815 E009 7.9514318 7.271846e-02 0.6402723827 0.95056070 1 40479016 40479035 20 + 0.909 0.990 0.304
ENSG00000187815 E010 69.1060811 2.145589e-04 0.0942881051 0.69333301 1 40479036 40479332 297 + 1.814 1.874 0.203
ENSG00000187815 E011 46.2957985 6.600647e-04 0.7589978281 0.97231201 1 40479333 40479488 156 + 1.667 1.682 0.049
ENSG00000187815 E012 33.3775100 5.464948e-03 0.6566782046 0.95485122 1 40481763 40481854 92 + 1.523 1.549 0.089
ENSG00000187815 E013 32.6113977 4.565350e-04 0.5934300436 0.94375317 1 40489088 40489145 58 + 1.540 1.513 -0.090
ENSG00000187815 E014 32.1659844 4.619959e-04 0.0142017321 0.39392095 1 40489146 40489214 69 + 1.581 1.454 -0.433
ENSG00000187815 E015 6.0536037 3.219933e-03 0.3792430629 0.89910707 1 40489526 40489528 3 + 0.894 0.800 -0.365
ENSG00000187815 E016 44.8933276 3.415347e-04 0.1081696584 0.71422330 1 40489529 40489624 96 + 1.696 1.626 -0.236
ENSG00000187815 E017 11.0876680 1.550228e-03 0.5326195193 0.93401086 1 40490780 40491156 377 + 1.108 1.056 -0.188
ENSG00000187815 E018 441.2480847 8.605627e-05 0.1754721410 0.79357629 1 40494921 40496667 1747 + 2.652 2.639 -0.042
ENSG00000187815 E019 0.0000000       1 40496761 40496787 27 +      

Help

Please Click HERE to learn more details about the results from DEXseq.