ENSG00000198945

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361794 ENSG00000198945 pgwt_inf pgKDN_inf L3MBTL3 protein_coding protein_coding 10.34327 13.71098 10.39239 1.398768 0.6321642 -0.3994688 1.0321082 1.3327731 0.8019218 0.5584068 0.5184973 -0.7258028 0.10944167 0.106250 0.084925 -0.021325 8.869824e-01 2.22059e-06 FALSE TRUE
ENST00000368136 ENSG00000198945 pgwt_inf pgKDN_inf L3MBTL3 protein_coding protein_coding 10.34327 13.71098 10.39239 1.398768 0.6321642 -0.3994688 0.5066797 0.0000000 0.0000000 0.0000000 0.0000000 0.0000000 0.08333333 0.000000 0.000000 0.000000   2.22059e-06 FALSE TRUE
ENST00000526019 ENSG00000198945 pgwt_inf pgKDN_inf L3MBTL3 protein_coding protein_coding 10.34327 13.71098 10.39239 1.398768 0.6321642 -0.3994688 0.7965275 0.4784241 1.9111584 0.4784241 0.4861536 1.9757702 0.07254167 0.034150 0.183475 0.149325 3.354578e-01 2.22059e-06 FALSE TRUE
ENST00000531313 ENSG00000198945 pgwt_inf pgKDN_inf L3MBTL3 protein_coding retained_intron 10.34327 13.71098 10.39239 1.398768 0.6321642 -0.3994688 1.8378639 5.5135916 0.0000000 1.4293863 0.0000000 -9.1094629 0.12871667 0.386150 0.000000 -0.386150 2.220590e-06 2.22059e-06   FALSE
ENST00000533560 ENSG00000198945 pgwt_inf pgKDN_inf L3MBTL3 protein_coding protein_coding 10.34327 13.71098 10.39239 1.398768 0.6321642 -0.3994688 4.2843280 4.5538045 6.2221335 1.6161187 0.8238225 0.4494891 0.44255833 0.369075 0.604425 0.235350 8.869824e-01 2.22059e-06 FALSE TRUE
MSTRG.25300.10 ENSG00000198945 pgwt_inf pgKDN_inf L3MBTL3 protein_coding   10.34327 13.71098 10.39239 1.398768 0.6321642 -0.3994688 0.9491500 1.2740481 0.0000000 1.2740481 0.0000000 -7.0045554 0.08359167 0.072575 0.000000 -0.072575 8.903016e-01 2.22059e-06 FALSE TRUE
MSTRG.25300.5 ENSG00000198945 pgwt_inf pgKDN_inf L3MBTL3 protein_coding   10.34327 13.71098 10.39239 1.398768 0.6321642 -0.3994688 0.6026936 0.0000000 1.4571724 0.0000000 0.9061169 7.1968946 0.05424167 0.000000 0.127175 0.127175 8.159294e-01 2.22059e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf pgwt.inf log2fold_pgwt.inf_pgKDN.inf
ENSG00000198945 E001 0.0000000       6 130013699 130013720 22 +      
ENSG00000198945 E002 0.0000000       6 130016226 130016292 67 +      
ENSG00000198945 E003 0.0000000       6 130018369 130018580 212 +      
ENSG00000198945 E004 0.0000000       6 130018581 130018582 2 +      
ENSG00000198945 E005 0.0000000       6 130018583 130018588 6 +      
ENSG00000198945 E006 1.2555684 0.0100085087 0.2105519617   6 130018589 130018664 76 + 0.434 0.241 -1.212
ENSG00000198945 E007 0.0000000       6 130019208 130019237 30 +      
ENSG00000198945 E008 0.0000000       6 130019367 130019463 97 +      
ENSG00000198945 E009 0.1293535 0.0123634025 0.5452005625   6 130020491 130020519 29 + 0.095 0.000 -9.085
ENSG00000198945 E010 0.2470310 0.0162974878 0.9921555191   6 130020520 130020556 37 + 0.095 0.096 0.010
ENSG00000198945 E011 0.7280132 0.0142984025 0.4061086087   6 130020557 130020668 112 + 0.173 0.299 1.010
ENSG00000198945 E012 3.6241004 0.0051928697 0.1017326738   6 130022227 130022305 79 + 0.753 0.541 -0.916
ENSG00000198945 E013 0.2454893 0.0162017058 0.9924178672   6 130025075 130025101 27 + 0.095 0.096 0.010
ENSG00000198945 E014 5.6807987 0.0026756422 0.8007618629 0.97959760 6 130042685 130042765 81 + 0.838 0.809 -0.115
ENSG00000198945 E015 4.5461192 0.0033157445 0.5962326323 0.94401404 6 130042766 130042801 36 + 0.714 0.774 0.245
ENSG00000198945 E016 7.3781521 0.0144434964 0.6031556634 0.94526316 6 130049282 130049393 112 + 0.896 0.950 0.203
ENSG00000198945 E017 0.0000000       6 130049651 130049755 105 +      
ENSG00000198945 E018 0.9761606 0.0124362782 0.4714280577   6 130049756 130049830 75 + 0.240 0.349 0.747
ENSG00000198945 E019 7.6642719 0.0022759259 0.6470246539 0.95251055 6 130051249 130051408 160 + 0.959 0.912 -0.176
ENSG00000198945 E020 8.8342253 0.0071665708 0.0975288351 0.69928299 6 130052859 130052991 133 + 1.063 0.899 -0.609
ENSG00000198945 E021 0.1278119 0.0122689601 0.5451061933   6 130055087 130055170 84 + 0.095 0.000 -9.086
ENSG00000198945 E022 8.3065326 0.0019062426 0.2932185564 0.86980441 6 130055171 130055255 85 + 1.014 0.912 -0.380
ENSG00000198945 E023 10.4256509 0.0014939622 0.2978289570 0.87145439 6 130057406 130057497 92 + 1.014 1.101 0.317
ENSG00000198945 E024 11.7722226 0.0013397519 0.0005079177 0.07425498 6 130060036 130060140 105 + 0.947 1.232 1.033
ENSG00000198945 E025 13.0334674 0.0012700994 0.5134970492 0.92953229 6 130066353 130066488 136 + 1.123 1.172 0.174
ENSG00000198945 E026 9.5466480 0.0083088833 0.3581938619 0.89451019 6 130068330 130068421 92 + 1.063 0.973 -0.329
ENSG00000198945 E027 0.0000000       6 130070847 130070975 129 +      
ENSG00000198945 E028 14.3282861 0.0038819128 0.0153039133 0.40359852 6 130070976 130071127 152 + 1.265 1.075 -0.680
ENSG00000198945 E029 6.9782820 0.0442544265 0.1282934866 0.74218820 6 130078558 130078634 77 + 0.982 0.792 -0.726
ENSG00000198945 E030 6.8077977 0.0042456893 0.5356327839 0.93401086 6 130083620 130083705 86 + 0.922 0.856 -0.253
ENSG00000198945 E031 8.4958522 0.0017635622 0.8636389630 0.98673729 6 130086140 130086250 111 + 0.971 0.985 0.052
ENSG00000198945 E032 10.5369245 0.0014780108 0.1733340819 0.79123778 6 130092745 130092859 115 + 1.004 1.118 0.415
ENSG00000198945 E033 11.9629596 0.0015016363 0.9664303883 0.99705064 6 130094265 130094367 103 + 1.115 1.109 -0.020
ENSG00000198945 E034 15.9341819 0.0016508476 0.7057363710 0.96635079 6 130104426 130104575 150 + 1.242 1.213 -0.102
ENSG00000198945 E035 4.6931013 0.0057204053 0.7771512453 0.97458395 6 130120879 130120958 80 + 0.771 0.736 -0.142
ENSG00000198945 E036 0.0000000       6 130133452 130133621 170 +      
ENSG00000198945 E037 6.8943094 0.0556588512 0.7980648015 0.97946189 6 130133843 130133905 63 + 0.882 0.912 0.113
ENSG00000198945 E038 62.7481793 0.0007409175 0.2141014624 0.82285636 6 130139610 130141449 1840 + 1.785 1.824 0.135

Help

Please Click HERE to learn more details about the results from DEXseq.